Sialorrhea clinical trials
The registry lists 56 studies for Sialorrhea across more than 10 countries. 6 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-08-07.
Status
- Completed
- 34
- Status unknown
- 10
- Not yet recruiting
- 4
- Withdrawn
- 4
- Active, not recruiting
- 2
- Recruiting
- 2
Phase
- Phase 2
- 14
- Phase 3
- 11
- Phase 4
- 2
- Early Phase 1
- 1
- Phase 1
- 1
Where
- United States
- 11
- France
- 5
- Egypt
- 4
- Spain
- 3
- Ukraine
- 3
- Israel
- 3
Who runs them
Cairo University (4) · Solstice Neurosciences, LLC, a subsidiary of US WorldMeds, LLC (3) · Merz Pharmaceuticals GmbH (2) · Beth Israel Deaconess Medical Center (2) · Hacettepe University (2) · Hospices Civils de Lyon (2) · Beersheva Mental Health Center (2) · NeuroHealing Pharmaceuticals Inc. (2)
Studies
Recruiting first, then most recently updated. Showing 50 of 56 — search for more.
- Local Vibration for Drooling in Children With Cerebral PalsyRecruitingNCT07626424Not applicable1 country
- Application of Neuro-electrostimulation as a Treatment for Patients With Dry MouthRecruitingNCT07593495Not applicable1 country
- Effectiveness of Neuromuscular Electrical Stimulation Added to Oral Motor Therapy in Cerebral PalsyNot yet recruitingNCT07069257Not applicable1 country
- Chewing Gum as a Therapeutic Intervention for the Management of HypersalivationNot yet recruitingNCT07158359Not applicable
- Effect of Stellate Ganglion Block on Drooling in Parkinson's SyndromeNot yet recruitingNCT06370195Not applicable
- Oral Structural and Functional Problems in Children With AutismNot yet recruitingNCT06355141
- Effects of Transcutaneous Vagus Nerve Stimulation in Parkinson´s DiseaseActive, not recruitingNCT07588191Not applicable1 country
- Cognitive-Integrated Soccer Training and PerformanceCompletedNCT07284940Not applicable1 country
- Post-Covid-19 Patients Follow-up StudyCompletedNCT07571382Not applicable1 country
- Open-Label and Single-Arm Study of MYOBLOC® in the Treatment of Troublesome Sialorrhea in AdultsCompletedNCT02610868Phase 33 countries
- A Multi-Center Study of MYOBLOC for the Treatment of Sialorrhea in Parkinson's Disease PatientsCompletedNCT00515437Phase 21 country
- Efficacy and Safety Study of MYOBLOC® in the Treatment of Sialorrhea in Adult SubjectsCompletedNCT01994109Phase 33 countries
- Effect of SCS Technique on Oromotor Skills in Children With CPActive, not recruitingNCT07516860Not applicable1 country
- Botulinum Toxin Injections Into the Salivary Glands of Cerebrospinal Children With Chronic SialorrheaCompletedNCT070677621 country
- The Application of Lidocaine Cream on Oral Secretions of LMA Removal During the Recovery Period in Ophthalmic Surgical Patients Under General AnesthesiaWithdrawnNCT06967064Phase 4
- Pharmacokinetics of Atropine Oral GelCompletedNCT05164367Early Phase 11 country
- Efficacy and Safety Study of MYOBLOC in the Treatment of Sialorrhea in Pediatric SubjectsWithdrawnNCT05097079Phase 3
- Botulinum Toxin Injection for Sialorrhea in Cerebral PalsyCompletedNCT061011601 country
- STN-DBS and the Risk of SialorrheaCompletedNCT06090929Not applicable1 country
- A Relative Efficacy and Safety Study of OC Oral Solution for Sialorrhoea in Patients With Parkinson's DiseaseCompletedNCT01370811Phase 21 country
- Prevalence of Sialorrhea in Patients Treated With ClozapineCompletedNCT041970371 country
- Kinesio Taping Versus Oromotor Training on Drooling in Children With Spastic Cerebral PalsyCompletedNCT05524831Not applicable1 country
- Double-blind, Placebo-controlled, Randomized Clinical Trial Comparing the Efficacy and Safety of Sialanar Plus orAl rehabiLitation Against Placebo Plus Oral Rehabilitation for chIldren and Adolescents With seVere Sialorrhoea and Neurodisabilties,Status unknownNCT04873115Phase 41 country
- Effects of Open and Closed System Suctioning on Suctioning Frequency and Amount of SecretionCompletedNCT04053751Not applicable1 country
- Safety and Efficacy of Cryoablation in Management of Sialorrhea in Patients With Neurological DisordersWithdrawnNCT03704168Not applicable
- Clinical Study to Investigate the Efficacy and Safety of NT 201 Compared to Placebo in the Treatment of Chronic Troublesome Drooling Associated With Neurological Disorders and/or Intellectual DisabilityCompletedNCT02270736Phase 36 countries
- Effectiveness of Kinesiotaping and Manipulation Therapies in Drooling Management Among Children With Oral DysphagiaStatus unknownNCT04266626Not applicable1 country
- Acute Salivary Flow Rate Response to Transcutaneous Electrical Nerve Stimulation Versus Electro-acupunctureStatus unknownNCT042113241 country
- Turkish Validation of The Drooling Impact ScaleStatus unknownNCT041327651 country
- Validation of the French Version of the Drooling Impact Scale in a Pediatric Cerebral Palsy PopulationCompletedNCT039863331 country
- Ipratropium Bromide Spray as Treatment for Sialorrhea in ChildrenStatus unknownNCT03747536Phase 2
- Study of Glycopyrrolate for Moderate-to-severe Sialorrhea in Parkinson's DiseaseStatus unknownNCT02382198Phase 21 country
- Clinical Study to Investigate the Efficacy and Safety of Two Dose Levels of NT 201 Versus Placebo in Treating Chronic Troublesome Sialorrhea in Various Neurological ConditionsCompletedNCT02091739Phase 32 countries
- Clozapine-induced Hypersalivation - Feasibility TrialCompletedNCT02613494Phase 1/21 country
- Effect of Functional Chewing Training on Tongue Thrust and Drooling in Children With Cerebral PalsyCompletedNCT03194048Not applicable
- Incobotulinum Toxin A (Xeomin®) for Troublesome Sialorrhea in Parkinson's Disease (PD)/ParkinsonismCompletedNCT01653132Phase 21 country
- Incobotulinum Toxin A for Sialorrhea in Parkinson's Disease (PD)/Parkinsonism and Amyotrophic Lateral Sclerosis (ALS)WithdrawnNCT01565395Phase 21 country
- Management of Drooling in Children With Cerebral Palsy in FranceCompletedNCT02797106
- Study of the Safety and Efficacy of Tropicamide Thin Films to Reduce Hypersalivation in Parkinson's PatientsCompletedNCT01844648Phase 21 country
- Safety and Efficacy Study of NH004 Films for Relief of Sialorrhea Symptoms in Parkinson's Disease PatientsCompletedNCT00761137Phase 21 country
- Toxin Treatment for Amyotrophic Lateral Sclerosis (ALS) Related SialorrheaCompletedNCT01551940Phase 21 country
- Botulinum Toxin-A for Sialorrhoea Treatment in Asian Adults With Neurological DiseasesCompletedNCT02425176Phase 2/31 country
- Oral Health Literacy Tailored CommunicationCompletedNCT01118143Not applicable1 country
- Efficacy of Passive Oral Motor Therapy on Drooling in Children With Multiple DisabilitiesCompletedNCT02333981Not applicable
- Metoclopramide as Treatment of Clozapine-induced HypersalivationCompletedNCT02222220Phase 31 country
- Effectiveness of Atropine and Glycopyrrolate to Reduce Hyper Salivation With Ketamine SedationCompletedNCT01191398Not applicable1 country
- Efficacy of Intravenous Glyco-P® in Patients Undergoing Procedure That Require Anesthesia ServiceCompletedNCT021025421 country
- Application of Botulinum Toxin Type A in Salivary Glands in the Treatment of Drooling in Patients With Cerebral PalsyStatus unknownNCT01489904Phase 2/31 country
- Benzamide Derivates as Treatment of Clozapine-induced HypersalivationCompletedNCT00534573Phase 31 country
- Safety and Efficacy Study of Oral Glycopyrrolate Liquid for the Treatment of Pathologic (Chronic Moderate to Severe) Drooling in Pediatric Patients 3 to 18 Years of Age With Cerebral Palsy or Other Neurologic ConditionsCompletedNCT00491894Phase 31 country