Shock, Septic: all 890 studies

Page 3 of 9. Open to participants first (210), then studies with results posted, then the rest; newest registration first within each.

• Septic Shock-induced ImmunosuppressionRecruitingNCT04067674
• Neuromodulation to Regulate Inflammation and Autonomic Imbalance in SepsisRecruitingNCT03992378Not applicable
• Study on the Efficacy and Timing of ECMO Therapy in Children With Refractory Septic ShockRecruitingNCT03948048
• Sevoflurane Sedation in Patients With Septic ShockNot yet recruitingNCT03643367Phase 2
• Does Urinary TIMP2 and IGFBP7 Can Identify High Risk Patients of Progression From Mild and Moderate to Severe Acute Kidney Injury During Septic Shock?RecruitingNCT03547414
• Stress Hydrocortisone In Pediatric Septic ShockRecruitingNCT03401398Phase 3
• Prospective, Randomized Trial of Personalized Medicine With Pentaglobin® After Surgical Infectious Source Control in Patients With PeritonitisRecruitingNCT03334006Phase 2
• Biomarkers in InfectionRecruitingNCT02545478
• Severe Sepsis/Septic Shock on Admission to the General Surgical ICURecruitingNCT01363635
• Alveolar Dead Space as Predictor of Organ Failure in Severe SepsisNot yet recruitingNCT01315782
• Serum Biomarkers to Predict Response to Angiotensin II in Septic ShockCompletedNCT05824767Phase 4Results posted
• Renin and Renal Biomarker Response to Angiotensin IICompletedNCT04558359Phase 4Results posted
• Early Metabolic Resuscitation for Septic ShockTerminatedNCT03895853Phase 2Results posted
• Albumin Replacement Therapy in Septic ShockTerminatedNCT03869385Phase 3Results posted
• A Trial of Vitamin B12 in Septic ShockCompletedNCT03783091Phase 2Results posted
• HCT+F vs. HCT Alone in Critically Ill Medical Septic Shock PatientsCompletedNCT03710187Phase 2Results posted
• Midodrine Use in Septic ShockTerminatedNCT03706053Phase 3Results posted
• The Conservative vs. Liberal Approach to Fluid Therapy of Septic Shock in Intensive Care TrialCompletedNCT03668236Phase 4Results posted
• Vitamin C & Thiamine to Treat Sepsis and Septic ShockCompletedNCT03592277Phase 2Results posted
• LIPIDS-P Trial Phase I/II TrialCompletedNCT03405870Phase 1/2Results posted
• Ascorbic Acid, Corticosteroids, and Thiamine in Sepsis (ACTS) TrialCompletedNCT03389555Phase 2/3Results posted
• Resuscitation With Plasma in Surgical and Trauma Patients With Septic ShockTerminatedNCT03366220Phase 2Results posted
• Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis: A Pilot Feasibility StudyCompletedNCT03340805Phase 1Results posted
• Vitamin C and Septic ShockCompletedNCT03338569Phase 2/3Results posted
• Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of 3 Doses of MOTREM (Nangibotide) in Patients With Septic ShockCompletedNCT03158948Phase 2Results posted
• Treatment of Patients With Early Septic Shock and Bio-Adrenomedullin(ADM) Concentration > 70 pg/ml With ADRECIZUMABCompletedNCT03085758Phase 2Results posted
• The Randomized Controlled Trial of Inferior Vena Cava Ultrasound-guided Fluid Management in Septic Shock ResuscitationCompletedNCT03020407Not applicableResults posted
• Amendment of rTSST-1 Variant Vaccine Phase 1 Clinical TrialCompletedNCT02971670Phase 1Results posted
• Evaluating the Effect of Chronic Antihypertensive Therapy on Vasopressor Dosing in Septic ShockCompletedNCT02884011Results posted
• Esmolol Infusion for Patients With Septic Shock and Persistent TachycardiaCompletedNCT02841241Phase 2Results posted
• Clinical Trial of the BioMed rTSST-1 Variant Vaccine in Healthy AdultsCompletedNCT02814708Phase 2Results posted
• Use of Amiodarone in Atrial Fibrillation Associated With Severe Sepsis or Septic ShockTerminatedNCT02668432Phase 4Results posted
• Initiation of Hydrocortisone for the Treatment of Septic ShockCompletedNCT02580240Not applicableResults posted
• Selepressin Evaluation Programme for Sepsis-Induced Shock - Adaptive Clinical TrialTerminatedNCT02508649Phase 2/3Results posted
• Fluid Balance in the ICU - Interventions to Minimize Fluids in Patients With Septic ShockCompletedNCT02473718Not applicableResults posted
• Esmolol to Treat the Hemodynamic Effects of Septic ShockTerminatedNCT02369900Phase 2Results posted
• rTSST-1 Variant Vaccine Phase 1 First-in-man TrailCompletedNCT02340338Phase 1Results posted
• Treatment of Septic Shock by Inhibiting Autodigestion and Preserving Gut Integrity With Enteric LB1148TerminatedNCT02317549Phase 2Results posted
• PK Analysis of Piperacillin in Septic Shock PatientsCompletedNCT02306928Results posted
• Phenylephrine Versus Norepinephrine for Septic Shock in Critically Ill PatientsTerminatedNCT02203630Phase 4Results posted
• Venous Lactate in Progression to Overt Septic Shock and Mortality in Non-elderly Sepsis Patients in Emergency DepartmentCompletedNCT01947127Results posted
• Rapid Administration of Carnitine in sEpsisCompletedNCT01665092Phase 2Results posted
• COMPACT 2 - COMbining Plasma-filtration and Adsorption Clinical Trial 2TerminatedNCT01639664Not applicableResults posted
• Investigating FE 202158 as Potential Primary Treatment in Patients With Early Septic ShockCompletedNCT01612676Phase 2Results posted
• High MAP in Septic Shock With HypertensionCompletedNCT01443494Not applicableResults posted
• Intravenous AII for the Treatment of Severe Hypotension in High Output Shock: A Pilot StudyCompletedNCT01393782Phase 1Results posted
• Pharmacokinetic and Biomarker Study of Pioglitazone in Adolescents With Severe Sepsis and Septic ShockCompletedNCT01352182Phase 1/2Results posted
• Hemodynamic and Inflammatory Effects of Abrupt Versus Tapered Corticosteroid Discontinuation in Septic ShockTerminatedNCT01150409Phase 4Results posted
• A Study to Compare the Efficacy and Safety of 2 Dosing Regimens of IV Infusions of AZD9773 (CytoFab™) With Placebo in Adult Patients With Severe Sepsis and/or Septic ShockCompletedNCT01145560Phase 2Results posted
• A Study to Assess Safety,and Tolerability of 2 Doses of AZD9773 (CytoFab™) in Japanese With Severe Sepsis/Septic ShockCompletedNCT01144624Phase 2Results posted
• Thiamine as a Metabolic Resuscitator in Septic ShockCompletedNCT01070810Phase 1/2Results posted
• Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Septic ShockCompletedNCT01046669Not applicableResults posted
• Effects of the V1a Agonist FE 202158 in Patients With Septic ShockCompletedNCT01000649Phase 2Results posted
• Statin Therapy in the Treatment of SepsisCompletedNCT00676897Phase 2/3Results posted
• Efficacy and Safety of Drotrecogin Alfa (Activated) in Adult Patients With Septic ShockCompletedNCT00604214Phase 3Results posted
• Dopamine Versus Norepinephrine for the Treatment of Vasopressor Dependent Septic ShockCompletedNCT00604019Phase 3Results posted
• Acetyl-L-Carnitine in the Treatment of Septic ShockCompletedNCT00592488Phase 1/2Results posted
• Minimally-Invasive Cardiovascular Hemodynamic Optimization (MiCHO) Versus Early Goal-Directed Therapy (EGDT) in the Management of Septic ShockTerminatedNCT00535821Phase 4Results posted
• Protocolized Care for Early Septic ShockCompletedNCT00510835Not applicableResults posted
• Hemodynamic and Perfusion Response to Drotrecogin Alfa (Activated) in Patients With Septic ShockCompletedNCT00279214Phase 4Results posted
• Internal Jugular Vein and Inferior Vena Cava Collapsibility Indices as a Guidance of Fluid Responsiveness in Septic Shock Cancer PatientsCompletedNCT07879287
• Comparing Blood-Based Ratios for Predicting Outcomes in Sepsis and Septic ShockCompletedNCT07819708
• Thiamine, Ascorbic Acid, and Their Combination on MMP-9/TIMP-1 and Inflammatory Balance in SepsisCompletedNCT07786350Not applicable
• Dopamine Versus Epinephrine for Pediatric Fluid-Refractory Hypotensive Septic ShockActive, not recruitingNCT07775001Not applicable
• Association of Arterio-Venous Oxygen and Carbon Dioxide Gradients With Tissue Hypoperfusion and Mortality in SepsisCompletedNCT07711405
• Continuous Infusion Versus Intermittent Bolus Hydrocortisone in Septic ShockCompletedNCT07695337Phase 4
• Occult Vasoplegia in Normotensive Sepsis: Early Prediction With Diastolic Index and LactateCompletedNCT07658014
• Metformine as a Protective Factor of Mortality in Type 2 Diabetic Patients Admitted to the ICU for Septic Shock.CompletedNCT07591402
• Use of Oxiris Filter in Septic Shock Patients Requiring Renal Replacement Therapy: A Retrospective Cohort StudyCompletedNCT07569406
• Comparison of Angiotensin II to Standard Dose Vasopressors on Change in Arterial ElastanceActive, not recruitingNCT07568275Early Phase 1
• Impact of Systematic Point-of-Care Ultrasound Implementation on Clinical Outcomes and Survival in Septic Shock: A Retrospective Single-Center Cohort StudyCompletedNCT07565649
• Comparative Efficacy and Safety of Propofol-Ketamine Combination Versus Propofol Monotherapy in Geriatric Patients Under Invasive VentilationActive, not recruitingNCT07530146Phase 3
• Implementation of Timely Management of Sepsis and Septic Shock Protocol in the Emergency Department and Intensive Care Unit: A Quality Improvement Project at AFHJCompletedNCT07460024Not applicable
• Multicenter Symphony™ IL-6 Monitoring Sepsis ED Pilot StudyActive, not recruitingNCT07425587
• Early and Late Neutrophil CD64 and Monocyte HLA-DR as Biomarkers for Septic ShockCompletedNCT07401329
• Early Continuous Renal Replacement Therapy for Pediatric Septic ShockActive, not recruitingNCT07370753
• ICU Admission Diagnoses and ICU MortalityCompletedNCT07369206
• Different Norepinephrine Doses on Accuracy of Peripheral Perfusion Index in Predicting Tissue Perfusion in Septic Shock PatientsCompletedNCT07330908Not applicable
• Outcome of Using Hydrocortisone in Early Treatment of Pediatric Septic ShockCompletedNCT07313670Not applicable
• Vasopressor Use Improves Macrocirculation, But What Are Its Effects on Microcirculation?CompletedNCT07312071Not applicable
• Validation of SOFA-2 for Mortality and Sepsis-3 Prevalence in TurkeyCompletedNCT07300306
• A Study in Healthy Subjects to Assess the Safety and Tolerability of a 120-hour Continuous Infusion of M6229CompletedNCT07285603Phase 1
• Population-Based Analysis of Incidence and Mortality of Septic ShockActive, not recruitingNCT07174765
• Guiding Fluid Resuscitation in Septic Shock: Ultrasound vs. Noninvasive Cardiac Output MonitoringCompletedNCT07162857Not applicable
• Selective Plasmofiltration for Abdominal Septic Shock: a Clinical CtudyCompletedNCT07121647Not applicable
• The PvCO2-PaCO2/CaO2-CvO2 Ratio in Septic ShockCompletedNCT07096284
• Critical Closing Pressure and PCO₂ Gap in Fluid Resuscitation for Septic ShockActive, not recruitingNCT07043192
• Evaluation of the Prognostic Value of Immature Platelet FractionCompletedNCT07039227
• Effect of Simulation Application in Septic Shock ManagementCompletedNCT07032779Not applicable
• Prospective Study Evaluating the Prevalence of Intestinal DysfunctionCompletedNCT07022548
• Hyperdynamic Left Ventricular Ejection Fraction as a Predictor of Mortality in Intensive Care Unit Patients With Septic ShockCompletedNCT06993948
• Evaluation of the Clinical Relationship Between Procalcitonin Level and Bacteremia Agent in Intensive Care Unit PatientsCompletedNCT06958354
• Vasopressin Use in Septic Shock From TürkiyeCompletedNCT06953297
• Adjunctive Methylene Blue in Septic ShockCompletedNCT06900140Phase 3
• Association of EASIX in SepsisCompletedNCT06887439
• The Effect of CUGP Fluid Management in Patients With Sepsis or Septic ShockCompletedNCT06879249Not applicable
• Comparison of Peripheral Perfusion Indicators and Lactate LevelsCompletedNCT06727318
• Multicenter Symphony IL-6 Monitoring Sepsis ICU Validation StudyActive, not recruitingNCT06654895
• Clearance of Antibacterial Agents During Hemoperfusion in Patients With SepsisCompletedNCT06602245
• Intravenous Metoprolol in Septic ShockCompletedNCT06592547Phase 2

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