Shock, Septic: all 890 studies

Page 5 of 9. Open to participants first (210), then studies with results posted, then the rest; newest registration first within each.

• Microcirculation Recruitment Using Albumin 20% and Terlipressin in Septic PatientsStatus unknownNCT05080543Phase 1
• Implementation Trial of Predictive Modeling to Enhance Diagnosis and Improve Treatment in Pediatric Septic ShockCompletedNCT05065333Not applicable
• Hemodynamic Phenotype and Capillary Refill Time-targeted Resuscitation StrategyStatus unknownNCT05057611Not applicable
• Interstitial Fluid Composition in Patients With Septic Versus Non-septic Shock: an Exploratory Pilot StudyCompletedNCT05039151
• Blood Purification for the Treatment of Pathogen Associated ShockActive, not recruitingNCT05011656Not applicable
• Hemodynamics Effects of Fludrocortisone on the Pressor Response to Noradrenaline Septic Shock PatientsSuspendedNCT05001854Phase 2/3
• Evaluation of Safety and Dosing of a Vitamin C Bundle for Sepsis Treatment in AfricaStatus unknownNCT04999137Phase 2
• Specific miRNAs in Sepsis and Nephrotoxic Antibiotic TreatmentCompletedNCT04991376
• The Effect of Early Use of Methylene Blue on Hemodynamics in Septic ShockStatus unknownNCT04970602Not applicable
• A RCT to Assess the Performance of CytoSorb for Shock Reversal in Patients With Vasoplegic Septic ShockSuspendedNCT04963920Not applicable
• Simplified Assessment of Left Ventricular Systolic Function in Septic Shock PatientsCompletedNCT04963686
• Advanced Mesenchymal Enhanced Cell THerapY for SepTic PatientsTerminatedNCT04961658Phase 1
• RRT With a Cytokine Absorption Filter (oXiris ®) in Patients With Septic ShockCompletedNCT04952714
• Effects of Terlipressin on Renal Perfusion in Patients With Septic ShockCompletedNCT04948372Not applicable
• OPTImized Restrictive Strategy Targeting Non-Resuscitative FLUIDs in Septic Shock: Pilot Study.CompletedNCT04947904Not applicable
• Protocolised Early De-Resuscitation in Septic Shock (REDUCE)CompletedNCT04931485Not applicable
• A Prediction Model of 28-day Mortality in Septic ShockStatus unknownNCT04915625
• Artificial Intelligence for Sepsis Prediction in ICUStatus unknownNCT04913181
• Cytokine Adsorption in Severe, Refractory Septic ShockCompletedNCT04910893Not applicable
• Efferon LPS Hemoperfusion for Treatment of Patients With Septic ShockCompletedNCT04884854
• Effects of Norepinephrine and Volume Expansion in Capillary Refill Time in Septic ShockStatus unknownNCT04870892
• MCO Membrane Efficiency in Septic Shock PatientsCompletedNCT04834921Not applicable
• Lipopolysaccharide Adsorption At Septic ShockCompletedNCT04827407Not applicable
• High-dose Intravenous Vitamin C in Patients With Septic ShockStatus unknownNCT04796636Phase 1
• Modulation of Endothelial Dysfonction Using Vitamin C in Septic Shock PatientsStatus unknownNCT04778605
• Fluid Resuscitation in Septic Shock Patients With BMI ElevationTerminatedNCT04759989Not applicable
• Early Administration of Vitamin C in Patients With Sepsis or Septic Shock in Emergency DepartmentsCompletedNCT04747795Phase 3
• Extracorporal Cytokin Removal in Septic Shock: a Prospective, Randomized, Multicenter Clinical TrialSuspendedNCT04742764Phase 3
• Septic Shock Management Guided by Ultrasound: SEPTICUS TrialStatus unknownNCT04728529Not applicable
• Evaluation of Plasma Angiotensin II and Angiotensin II Receptor Levels in Patients With Sepsis and Septic Shock: a Prospective Observational Study.Status unknownNCT04716842
• Comparison of Extubation Delay After Prolonged SedationTerminatedNCT04710914Phase 4
• Validation of Uncalibrated Cardiac Output Measurement With LiDCOrapid in the Resuscitation of Critically Ill Patients With Septic Shock: A Prospective Cross-sectional Study.CompletedNCT04705493
• Impact of COVID-19 on the Incidence, Characteristics, Management and Outcome of SepsisWithdrawnNCT04698382
• Sepsis in the ICU-IIActive, not recruitingNCT04695119
• Capillary Refill Time Response to a Rapid Fluid Challenge in Septic Shock PatientsStatus unknownNCT04693923Not applicable
• Cerebral Hemodynamics and Oxygenation in Critically Ill PatientsWithdrawnNCT04690530
• Erythromycin in Septic Patients: Immunomodulatory Role and Clinical ImpactCompletedNCT04665089Not applicable
• Effects of Hydrocortison Treatment on Angiotensin II and Angiotensin II Receptors in Patients With Septic ShockCompletedNCT04647552
• Rotational Thromboelastometry Versus DIC Score in SepsisCompletedNCT04610853
• Assessment of Microcirculatory Dysfunction in Septic Shock Patients by OCTATerminatedNCT04593212
• Does High-dose Vitamin B3 Supplementation Prevent Major Adverse Kidney Events During Septic Shock?Active, not recruitingNCT04589546Phase 3
• Study Assessing Efficacy of Plasmatherapy in Septic Shock-induced Coagulopathy: Feasibility StudyCompletedNCT04580563Not applicable
• Role and Mechanisms of Lipid and Lipoprotein Dysregulation in SepsisCompletedNCT04576819
• Optimization of Sepsis Therapy Based on Patient-specific Digital Precision DiagnosticsCompletedNCT04571801Not applicable
• Australasian Resuscitation In Sepsis Evaluation: FLUid or Vasopressors In Emergency Department SepsisActive, not recruitingNCT04569942Phase 3
• Muscle Ultrasound Study in Shock PatientsCompletedNCT04550143
• Whether a Minimal Volume Could Predict Fluid Responsiveness Using Thermodilution by PAC in Septic Shock PatientsStatus unknownNCT04515511Not applicable
• Triple Therapy in Septic Shock PatientsCompletedNCT04508946Phase 3
• Acetated Ringer's Solution Versus Saline in Patients With Septic ShockStatus unknownNCT04507672Not applicable
• Fludrocortisone Dose Response Relationship in Septic Shock - FluDReSSCompletedNCT04494789Phase 2
• Evaluation of the Role of Hydrocortisone Either Alone or Combined With Fludrocortisone in the Outcome of Septic Shock in AdultsCompletedNCT04492280Phase 4
• Correlation of VEGF-A and Fluid Balance in Septic ShockCompletedNCT04474431Not applicable
• Pharmacokinetics of Amikacin and Cefuroxime in Critically Ill Patients.Status unknownNCT04470973
• Carotid Doppler and EEOT for Fluid Responsiveness PredictionCompletedNCT04470856Not applicable
• As an Early Indicator Biomarker of Prognosis and Mortality in Children With Sepsis and Septic Shock: suPARCompletedNCT04459572Not applicable
• Bicarbonated Ringer's Solution Versus Lactated Ringer's Solution in Patients With Septic ShockStatus unknownNCT04449757Not applicable
• Methylene Blue in Early Septic ShockCompletedNCT04446871Phase 2/3
• A Study Looking at the Use of Biomarkers to Provide Early Indication of Acute Kidney Injury in Patients With Sepsis (Limiting AKI Progression In Sepsis)TerminatedNCT04434209Not applicable
• Ratio of ''Central Venous-to-Arterial Co2 Gap'' to ''Arterial-to-Central Venous O2 Content Gap'' in Septic ShockStatus unknownNCT04425161
• Reference Range for abioSCOPE® Device With the PSP Assay in a Generally Healthy Adult PopulationCompletedNCT04409561
• Hemodynamic Optimisation Guided With Transcranial Doppler in Septic ShockStatus unknownNCT04398069Not applicable
• Fluid REsponsiveness and Arterial ELASTANCE in Patients With Septic Shock or After Aortic SurgeryStatus unknownNCT04388267
• Low-chlorine Vs High-chlorine Crystalloids in Septic Shock AdultsStatus unknownNCT04365010Phase 4
• Evaluating the Use of Polymyxin B Cartridge Hemoperfusion for Patients With Septic Shock and COVID 19No longer availableNCT04352985
• Evaluation of Sepsis-induced Immunosuppression Base on QuantiFERON Monitor® in Septic ShockWithdrawnNCT04320394Not applicable
• Mechanisms for Organ Dysfunction in Covid-19CompletedNCT04316884
• Observational Trial on Cytokine Adsorption in SepsisStatus unknownNCT04306419
• Norepinephrine / Vasopressin Combination for Resuscitation in Septic ShockCompletedNCT04302584Not applicable
• Methylene Blue and Microcirculation in Septic ShockStatus unknownNCT04295993Phase 3
• The Effect of Restrictive Fluid Management on Cardiac Function and Glycocalyx DegradationCompletedNCT04282252Phase 4
• Relation Between Mean Arterial Pressure and Renal Resistive Index in the Early Phase of Septic ShockCompletedNCT04281277Not applicable
• Improvement of Cerebrovascular Autoregulation in Patients With Septic Shock Due to Cytokine EliminationStatus unknownNCT04259567Not applicable
• Monitoring of Piperacillin-Tazobactam and Meropenem Plasmatic Levels in Critical PatientsStatus unknownNCT04257838
• VBI-S for the Treatment of Hypotension in Hypovolemic Septic Shock PatientsActive, not recruitingNCT04257136Phase 2
• Therapeutic Plasmaexchange in Early Septic ShockCompletedNCT04231994Phase 2
• Extracorporeal Cytokine Removal in Patients With Septic Shock in an Adult Intensive Care UnitStatus unknownNCT04231695
• Control of Fever in Septic PatientsCompletedNCT04227652Not applicable
• Study of the Role of Interferon αon the Endothelial Dysfunction During Septic ShockStatus unknownNCT04204694
• Procalcitonin and Antimicrobial Utilization in Critically Ill Cancer Patients with SepsisTerminatedNCT04203524Not applicable
• Vitamin C, Thiamine, Cyanocobalamine, Pyridoxine and Hydrocortisone in SepsisCompletedNCT04197115Phase 3
• Efficacy and Safety of Therapy With IgM-enriched Immunoglobulin With a Personalized Dose vs Standard Dose in Patients With Septic Shock.Status unknownNCT04182737Phase 3
• Personalized Dose Optimization of Amikacin Guided by Pharmacokinetic Modeling Software in Patients With Septic ShockCompletedNCT04178148Not applicable
• Effect of Fluid Deresuscitation With Central Venous Pressure Target 0-4 mmHg in Septic Shock PatientsCompletedNCT04156451Not applicable
• Time to Lose the Weight? Comparison of Weight-based and Non-weight-based Vasopressors for Septic ShockCompletedNCT04153578
• Safety and Efficiency of Combined Extracorporeal Blood Purification in Neurosurgical ICU. Prospective RCTStatus unknownNCT04152174Not applicable
• Hemodynamic Resuscitation and Monitoring in Early SepsisStatus unknownNCT04143035
• Global Longitudinal Strain Assessment in Cardiogenic Shock During SepsisStatus unknownNCT04141410
• The Effect of Increasing the Mean Arterial Pressure on the Microcirculation and the Prognosis of Patients With Septic ShockStatus unknownNCT04136080Not applicable
• EMS Prehospital Blood Culture Collection and Antibiotic Administration: A Two-Phase Pilot Project to Reduce Mortality in Patients With Severe Sepsis and Septic ShockTerminatedNCT04134624Not applicable
• Steroids, Thiamine and Ascorbic Acid in Septic ShockStatus unknownNCT04134403Phase 3
• Adjuvant Use of Neostigmine in Sepsis and Septic Shock.CompletedNCT04130230Phase 2
• Infusion of Prostacyclin (Iloprost) vs Placebo for 72-hours in Patients With Septic Shock Suffering From Organ FailureCompletedNCT04123444Phase 2/3
• Fluid Overload Quantification in Septic ShockCompletedNCT04114162
• Pilot Study on the Use of Hydrocortisone, Vitamin c and Tiamine in Patient With Sepsis and Septic ShockCompletedNCT04111822Phase 3
• Methylene Blue Versus Vasopressin Analogue for Treatment of Septic Shock in Preterm NeonateStatus unknownNCT04110418Phase 2
• PLatelets Acetyl-CoA Carboxylase Phosphorylation State in SEPtic ShockCompletedNCT04107402Not applicable
• Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in SepsisCompletedNCT04102371Phase 3
• Methylene Blue as a Third-line Vasopressor in Septic ShockStatus unknownNCT04089072Phase 2
• Pro-inflammatory Role of Blood Platelets in Critically Ill Patients With Septic Shock.CompletedNCT04080453
• Postoperative Respiratory AbnormalitiesStatus unknownNCT04079829

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