Scleroderma, Diffuse: all 534 studies
Page 1 of 6. Open to participants first (115), then studies with results posted, then the rest; newest registration first within each.
- A Clinical Study on Systemic Sclerosis and the Validation of French-language Questionnaires Assessing Disability, Quality of Life, and Disease Status.Not yet recruitingNCT07888842
- A Study of BMS-986553 in Participants With Refractory Autoimmune DiseasesNot yet recruitingNCT07873931Phase 1
- C-CAR168, an Autologous Anti-CD20/BCMA Chimeric Antigen Receptor T-Cell Therapy, in Participants With Systemic Sclerosis (SSc) Refractory to Standard TherapyNot yet recruitingNCT07854483Phase 1
- The Effect of Progressive Muscle Relaxation Exercises on Fatigue, Dyspnea, and Respiratory Function in Patients With Systemic SclerosisRecruitingNCT07842133Not applicable
- Home-based Exercise for Improving Health-related Quality of Life in Systemic SclerosisNot yet recruitingNCT07840430Not applicable
- TL1A Inhibition in Systemic Sclerosis-Related Skin Fibrosis and Immunological Alterations: A Proof-of-Concept In Vitro Study (FIBROSTOP)Not yet recruitingNCT07642297
- A Phase 1/2 Study of PRO-203 in Healthy Volunteers and Participants With Systemic Sclerosis.RecruitingNCT07641634Phase 1/2
- Allogeneic CD19/BCMA-Targeted CAR-γδT Cell Therapy: Safety and Preliminary Pharmacodynamics in Relapsed/Refractory Autoimmune DiseasesNot yet recruitingNCT07490275Phase 1
- Controlling Hyperactive Immunity With Long-lived LymphocytesRecruitingNCT07473154Phase 1/2
- Clinical Study of EVM18001 in the Treatment of Refractory Autoimmune DiseasesRecruitingNCT07470151Not applicable
- YTS109 in Pediatric Relapsed/Refractory Autoimmune DiseasesNot yet recruitingNCT07439029Phase 1
- Investigating the Effectiveness of the Biopsychosocial Model-Based Exercise Approach in Children and Adults Diagnosed With SclerodermaRecruitingNCT07292961Not applicable
- EncompaSSc: Evaluation of MTX-474 in Participants With Diffuse Cutaneous Systemic Sclerosis (dcSSc)RecruitingNCT07287670Phase 2
- A Phase 1 Open-label Study to Evaluate Safety in Healthy Participants and Participants With Autoimmune DiseasesRecruitingNCT07284797Phase 1
- Transcriptomic Study of Cutaneous Fibroblasts in SclerodermaRecruitingNCT07256418
- Patients Diagnosed With Scleroderma: Physical Performance and FunctionalityRecruitingNCT07183072
- Patients Diagnosed With Scleroderma and Their Chewing and Swallowing PerformanceRecruitingNCT07182981
- Cultural Adaptation, Validity, and Reliability of the Turkish Version of The PASTUL QuestionnaireRecruitingNCT07182968
- A Study of Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune DiseasesRecruitingNCT07115745Phase 1
- Diffuse Cutaneous Scleroderma (DSSc) SFDI StudyRecruitingNCT07090226Not applicable
- A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune DiseaseRecruitingNCT07085104Phase 1
- A Study of Nemolizumab for the Treatment of Adults With Systemic SclerosisRecruitingNCT07047690Phase 2
- PPI Refractory - GERD Mechanisms in Systemic SclerosisNot yet recruitingNCT07022912
- Pathogenic Mechanisms Involved in the Initiation and Progression of Systemic SclerosisNot yet recruitingNCT07015060Not applicable
- Medical Follow-up of New Cases of Polyarthritis in Children and Young AdultsRecruitingNCT07000916
- AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.RecruitingNCT06991114Phase 2
- Clinical Study on the Treatment of Systemic Sclerosis With UTAA91 Injection.Not yet recruitingNCT06982534Early Phase 1
- Safety and Efficacy of Baricitinib on Skin Tightening in Diffuse Cutaneous Systemic Sclerosis: A Comparative Study With MethotrexateRecruitingNCT06936215Phase 3
- A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune DiseaseRecruitingNCT06925542Phase 1
- DERMATOMICS: Identifying Regulators of Skin HomeostasisRecruitingNCT06894654
- Mesenchymal Stem Cells Infusion in Patients With Autoimmune DiseasesEnrolling by invitationNCT06888973Phase 1/2
- Clinical Study of CD7 CAR-T Cells for Relapsed/refractory Autoimmune DiseasesNot yet recruitingNCT06871644Not applicable
- Home-Based Clinical Management of Cardiac Complications in Systemic SclerosisRecruitingNCT06865118
- Chester Step Test: is It Effective in Scleroderma Patients?Not yet recruitingNCT06859567Not applicable
- Elastography Ultrasound in Localized Scleroderma (Morphea) StudyEnrolling by invitationNCT06847750
- Efficacy and Safety of HN2301 in Autoimmune Diseases（AIDs）RecruitingNCT06801119Phase 1
- Ultrasound and Electrophysiology Study of Hand in Systemic Sclerosis Patients and Contributors of Hand DysfunctionNot yet recruitingNCT06776575
- Relationship Between Pelvic Floor Dysfunctions and Sexual Dysfunction in Female Patients with Systemic SclerosisNot yet recruitingNCT06769399
- Vaccination Against Herpes Zoster in Patients With Inflammatory Rheumatic DiseasesEnrolling by invitationNCT06763783Phase 4
- A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)RecruitingNCT06733935Phase 1/2
- Home Based Clinical Management of Interstitial Lung Disease in Systemic Rheumatic DiseasesRecruitingNCT06732674Not applicable
- Phase I/II Randomized Clinical Trial of Allogeneic Adipose Tissue-derived Mesenchymal Stromal Cells Systemic Infusion in Severe Systemic SclerosisNot yet recruitingNCT06722105Phase 1/2
- A Study to Investigate the Long-term Safety and Efficacy of Belimumab in Adults With Interstitial Lung Disease (ILD) Associated With Systemic Sclerosis (SSc) and Other Connective Tissue Diseases (CTD) (BLISSconneCTD-OLE)RecruitingNCT06716606Phase 3
- US Zamto-cel Autoimmune DiseasesRecruitingNCT06708845Phase 1
- Anti-CD19 CAR T-Cell Therapy in Refractory Systemic Autoimmune DiseasesRecruitingNCT06685042Phase 1/2
- Respiratory Muscle Training in SclerodermaNot yet recruitingNCT06684132Not applicable
- Ultrasonic COmparison of Salivary Glands in Autoimmune Diseases (COUGAR)Not yet recruitingNCT06680310
- The Apollo Device in Systemic Sclerosis for the Management of fatiguE, Raynaud Phenomenon and qualiTy of LifeRecruitingNCT06675344Not applicable
- Rare AutoImmune SElf-management Programme DevelopmentRecruitingNCT06642870
- Assessment of Serum CD25 Level in Systemic Sclerosis Patients with or Without Interstitial Lung Disease (ILD)Not yet recruitingNCT06615128
- Investigation of Respiratory Muscle Sarcopenia in Patients with Systemic SclerosisRecruitingNCT06598982
- Functional Performance and Biopsychosocial Characteristics in Individuals with Systemic SclerosisRecruitingNCT06594302
- ROLE of PLATELETS in the PATHOPHYSIOLOGY of SYSTEMIC LUPUSRecruitingNCT06593041
- 6-minute Pegboard Ring Test in Patients with SclerodermaNot yet recruitingNCT06588959
- Nailfold Capillaroscopic Pattern Changes and Its Correlation with Interstitial Lung Disease (ILD) in Systemic Sclerosis (SSc) Patients.Not yet recruitingNCT06579651
- Respiratory Muscle Strength and Aerobic Capacity in SclerodermaRecruitingNCT06554132
- The Safety and Efficacy of Telitacicept in the Treatment of Systemic SclerosisRecruitingNCT06546540Phase 4
- 89Zr-Oxine-RY_SW01 Cell Injection for the Treatment of Systemic SclerosisNot yet recruitingNCT06489652Phase 1
- Connective Tissue Massage in SclerodermaRecruitingNCT06474910Not applicable
- Neutrophil Extracellular Traps in Different Forms of Systemic SclerosisRecruitingNCT06462768
- Relmacabtagene Autoleucel for the Treatment of Systemic SclerosisRecruitingNCT06414135Phase 1
- Evaluation of Patients With Systemic Sclerosis Without Specific or Associated AutoantibodiesNot yet recruitingNCT06412614
- Clinico-biological Collection of Autoimmune, Dysimmune or Auto-inflammatory Dermatological DiseasesRecruitingNCT06387654
- Efficacy and Safety of Telitacicept in the Treatment of Systemic SclerosisRecruitingNCT06375005Phase 2
- RESET-SSc: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201, a CD19-CAR T Cell Therapy, in Subjects With Systemic SclerosisRecruitingNCT06328777Phase 2/3
- Renal Assessment for Early Detection of Renal Impairment in Systemic Sclerosis and Systemic Lupus Erythematosus PatientsNot yet recruitingNCT06287125
- Delving Into Participation Trends of Scleroderma Clinical TrialsNot yet recruitingNCT06264492
- Study of Diosmin for the Treatment of Digital Ulcers in Systemic SclerosisRecruitingNCT06256575Not applicable
- Platform Clinical Study for Conquering SclerodermaRecruitingNCT06195072Phase 2
- A Randomized, Double-blind, Placebo-controlled Phase II Clinical Study to Evaluate the Safety, Tolerability, Efficacy, and Pharmacokinetic Profile of Genakumab Injection in Patients With Connective Tissue Disease-associated Interstitial Lung DiseaseRecruitingNCT06189495Phase 2
- Periodontal Microbiota in Systemic SclerosisRecruitingNCT06182293Not applicable
- Safety and Efficacy of Topical Sodium Metabisulfite for the Treatment of Calcinosis in Patients With Systemic SclerosisNot yet recruitingNCT06155578Phase 1/2
- Subcutaneous Semaglutide in Systemic SclerodermaRecruitingNCT06149260Phase 1
- Hand Function Impairment in Systemic Sclerosis: Outcomes, Mechanisms and Experience (HANDSOME)RecruitingNCT06133244
- "Pulmonary Rehabilitation Program in Patients With Interstitial Lung Disease Associated With Systemic Sclerosis"RecruitingNCT06105073
- RY_SW01 Cell Injection Therapy in Systemic SclerosisRecruitingNCT06058091Phase 1/2
- Safety and Efficacy of CD19 Targeted CAR-T Therapy for Refractory Autoimmune DiseaseRecruitingNCT06056921Phase 1
- Evaluation of Muscle Involvement in Systemic SclerosisRecruitingNCT06051773
- Effectiveness of Tofacitinib in Systemic SclerosisRecruitingNCT06044844Phase 2
- Juvenile Systemic Sclerosis, a Retrospective Epidemiological Study on a French CohortRecruitingNCT06019234
- Acceptance and Effectiveness of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2) Vaccination in Systemic Sclerosis Patients Treated by Autologous Hematopoietic Stem Cell TransplantationNot yet recruitingNCT05960058
- Manufacturing of Allogeneic Adipose Tissue-derived Mesenchymal Stromal Cells for Treatment of Severe Systemic SclerosisNot yet recruitingNCT05947682Not applicable
- Study to Evaluate the Efficacy, Safety, and Tolerability of Efzofitimod in Patients With Systemic Sclerosis (SSc)-Related Interstitial Lung Disease (ILD) (SSc-ILD)RecruitingNCT05892614Phase 2
- A Study of the Efficacy and Safety of Belimumab in Adults With Systemic Sclerosis Associated Interstitial Lung DiseaseRecruitingNCT05878717Phase 2/3
- Effectiveness of ESWT and PNF in Scleroderma With CalcinosisNot yet recruitingNCT05870852Not applicable
- Leap Motion Based Gamefication Exercises in the Individuals With Systemic SclerosisNot yet recruitingNCT05821335Not applicable
- Evaluation of HRCT Patterns in Systemic Sclerosis-associated Interstitial Lung DiseaseRecruitingNCT05482607
- Interstitial Lung Disease Trajectories in Patients With Systemic SclerosisRecruitingNCT05345795
- Clinico-biological Collection to Investigate the Physiopathology of Systemic Autoimmune DiseasesRecruitingNCT05251415
- Periodontal Health Status in Patients with Systemic SclerosisRecruitingNCT05215431Not applicable
- Effectiveness of Bosentan Therapy in Patients With Systemic scleRosis and Progressive Digital ulcEr Disease.RecruitingNCT05168215
- ADRCs in The Treatment of Hand Dysfunction Due to SclerodermaNot yet recruitingNCT05148598Phase 3
- PET Imaging of Systemic Sclerosis Using FDG and 68Ga-DOTA-Siglec-9Enrolling by invitationNCT05108857
- What is the Optimal Follow-up for Patients With Systemic Sclerosis?Not yet recruitingNCT05103553Not applicable
- Preventive Effect of Clopidogrel on the Systemic Sclerosis Development RiskRecruitingNCT05098704Phase 2/3
- Rehabilitation Program in Patients With SclerodermaRecruitingNCT05041868Not applicable
- ILD-SARDs Registry and BiorepositoryRecruitingNCT05007340
- Extracorporeal Photopheresis in Early Diffuse Cutaneous Systemic SclerosisRecruitingNCT04986605Phase 2
- Calcinosis Reduction by Pyrophosphate in SSCNot yet recruitingNCT04966416Not applicable
- Search for Diagnostic and Prognostic Biomarkers in Systemic Sclerosis and Inflammatory MyopathiesRecruitingNCT04917705Not applicable