Scleroderma, Diffuse: all 534 studies

Page 2 of 6. Open to participants first (115), then studies with results posted, then the rest; newest registration first within each.

• UVA-1 for Treatment of Skin Tightening and Improvement of Hand Function in SclerodermaEnrolling by invitationNCT04875078Not applicable
• Sildenafil for Early Pulmonary Vascular Disease in SclerodermaRecruitingNCT04797286Phase 2
• Lung Clearance Index to Identify Scleroderma Patients at Risk for ILDRecruitingNCT04535245
• Rheumatology Patient Registry and BiorepositoryRecruitingNCT04402086
• Pilot Study of Description of Cicatrisation Rates of Digital Ulcers in Systemic SclerodermaRecruitingNCT04319120
• Cohort of Patients With Systemic Sclerosis Within the Framework of the RESO Reference CentreRecruitingNCT04265144Not applicable
• Connective Tissue Diseases and Lung ManifestationsRecruitingNCT04095351
• Skeletal Muscle Function in Interstitial Lung DiseaseRecruitingNCT03800017Not applicable
• Autologous Stem Cell Transplantation in Patients With Systemic SclerosisRecruitingNCT03630211Phase 2
• Meir Medical Center Rheumatologic BiobankRecruitingNCT03473912
• Maternal Autoimmune Disease Research Alliance (MADRA) RegistryRecruitingNCT03276923
• New Orleans Pulmonary Hypertension BiobankRecruitingNCT03269630
• Mesenchymal Stromal Cells as Treatment for Digital Ulcers in Systemic SclerosisRecruitingNCT03211793Phase 1/2
• Comparative Autoantibody and Immunologic Cell Marker StudyEnrolling by invitationNCT02422875
• Scleroderma Registry & Repository at the Hospital for Special SurgeryRecruitingNCT01656447
• TENS in SclerodermaCompletedNCT06646913Not applicableResults posted
• An Open-label Extension Trial of HZNP-HZN-825-301 in Adult Participants With Diffuse Cutaneous Systemic Sclerosis (Diffuse Cutaneous SSc)TerminatedNCT05626751Phase 2Results posted
• A Study to Assess the Effect of Oral Temanogrel on Digital Blood Flow in Adult Participants With Raynaud's Phenomenon Secondary to Systemic SclerosisTerminatedNCT04915950Phase 2Results posted
• Apollo Device for Fatigue in Systemic SclerosisCompletedNCT04854850Not applicableResults posted
• A Study to Evaluate the Safety and Tolerability of Oral Ixazomib in Scleroderma-related Lung Disease PatientsTerminatedNCT04837131Phase 2Results posted
• A Multicenter Trial to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of HZN-825 in Patients With Diffuse Cutaneous Systemic SclerosisTerminatedNCT04781543Phase 2Results posted
• A Study to Investigate Safety of GS-248 and Efficacy on Raynauds' Phenomenon in Systemic SclerosisCompletedNCT04744207Phase 2Results posted
• Efficacy and Safety of Belumosudil in Subjects With Diffuse Cutaneous Systemic SclerosisTerminatedNCT04680975Phase 2Results posted
• Effects of FT011 in Systemic SclerosisCompletedNCT04647890Phase 2Results posted
• Laser Treatment for the Improvement of Scars and SclerodermaTerminatedNCT04567537Not applicableResults posted
• A Study With TEPEZZA in Patients With Diffuse Cutaneous Systemic Sclerosis (dcSSc)TerminatedNCT04478994Phase 1Results posted
• Study to Evaluate Efficacy, Safety, and Tolerability of MT-7117 in Subjects With Diffuse Cutaneous Systemic SclerosisCompletedNCT04440592Phase 2Results posted
• Cold Challenge With C21 in RPCompletedNCT04388176Phase 2Results posted
• The Effect of a Home-based Orofacial Exercise Program on Oral Aperture of Systemic Sclerosis PatientsCompletedNCT04336475Not applicableResults posted
• Evaluation of the Scleroderma Patient-centered Intervention Network COVID-19 Home-isolation Activities Together ProgramCompletedNCT04335279Not applicableResults posted
• Safety and Pharmacokinetics of IgPro20 and IgPro10 in Adults With Systemic Sclerosis (SSc)CompletedNCT04137224Phase 2Results posted
• Intravenous Iloprost in Subjects With Symptomatic Raynaud's Phenomenon Secondary to Systemic Sclerosis (Phase 3)CompletedNCT04040322Phase 3Results posted
• A Clinical Study to Test Long Term Safety of GLPG1690 for Patients With Systemic SclerosisTerminatedNCT03976648Phase 2Results posted
• KD025 in Subjects With Diffuse Cutaneous Systemic SclerosisTerminatedNCT03919799Phase 2Results posted
• Intravenous Iloprost in Subjects With Symptomatic Raynaud's Phenomenon Secondary to Systemic Sclerosis (Phase 2)CompletedNCT03867097Phase 2Results posted
• A Clinical Study to Test How Effective and Safe GLPG1690 is for Participants With Systemic SclerosisCompletedNCT03798366Phase 2Results posted
• A Study of FCX-013 Plus Veledimex for the Treatment of Moderate to Severe Localized Scleroderma (Morphea)TerminatedNCT03740724Phase 1/2Results posted
• A Study to Test Whether Nintedanib Influences the Components of Birth-control Pills in Women With Systemic Sclerosis Associated Interstitial Lung Disease (SSc-ILD)CompletedNCT03675581Phase 1Results posted
• Cardiac Safe Transplants for Systemic SclerosisTerminatedNCT03593902Phase 2/3Results posted
• The Scleroderma Patient-centered Intervention Network (SPIN) Support Group Leader Education Program Feasibility TrialCompletedNCT03508661Not applicableResults posted
• Evaluation of Tofacitinib in Early Diffuse Cutaneous Systemic Sclerosis (dcSSc)CompletedNCT03274076Phase 1/2Results posted
• Brentuximab Vedotin for Systemic SclerosisCompletedNCT03222492Phase 1/2Results posted
• Scleroderma Lung Study III - Combining Pirfenidone With MycophenolateCompletedNCT03221257Phase 2Results posted
• Scleroderma Patient-centered Intervention Network (SPIN) Hand Program Feasibility StudyCompletedNCT03092024Not applicableResults posted
• Injection of Autologous Adipose-derived Stromal Vascular Fraction in the Finger of Systemic Sclerosis PatientsCompletedNCT03060551Early Phase 1Results posted
• Proof of Mechanism Study of GSK2330811 in Diffuse Cutaneous Systemic SclerosisCompletedNCT03041025Phase 2Results posted
• Dimethyl Fumarate (DMF) in Systemic Sclerosis-Associated Pulmonary Arterial HypertensionTerminatedNCT02981082Phase 1Results posted
• Effectiveness and Safety of SAR156597 in Treating Diffuse Systemic SclerosisCompletedNCT02921971Phase 2Results posted
• Riociguat in Scleroderma Associated Digital UlcersCompletedNCT02915835Phase 2Results posted
• Abituzumab in SSc-ILDTerminatedNCT02745145Phase 2Results posted
• Safety and Efficacy of Oral Treprostinil in the Treatment of Calcinosis in Patients With Systemic SclerosisCompletedNCT02663895Phase 2Results posted
• Hands on - a Hand Care Guide in Systemic SclerosisCompletedNCT02610842Not applicableResults posted
• A Trial to Compare Nintedanib With Placebo for Patients With Scleroderma Related Lung FibrosisCompletedNCT02597933Phase 3Results posted
• Systemic Sclerosis (SSc) Vasculopathy: Improved Clinical Monitoring and TreatmentCompletedNCT02530996Phase 1/2Results posted
• Taking Charge of Systemic SclerosisCompletedNCT02494401Not applicableResults posted
• Safety, Tolerability, Efficacy, and Pharmacokinetics of JBT-101 in Systemic SclerosisTerminatedNCT02465437Phase 2Results posted
• A Study of the Efficacy and Safety of Tocilizumab in Participants With Systemic Sclerosis (SSc)CompletedNCT02453256Phase 3Results posted
• Exparel as a Nerve Block for Severe Hand PainTerminatedNCT02374320Phase 2/3Results posted
• Atorvastatin for Microvascular Endothelial Function and Raynaud in Early Diffuse SclerodermaCompletedNCT02370784Phase 2Results posted
• Comparing and Combining Bortezomib and Mycophenolate in SSc Pulmonary FibrosisCompletedNCT02370693Phase 2Results posted
• Long Term Effect of Buspirone on Esophageal Function and Esophageal Symptoms in Patients With Systematic Sclerosis (SSc)CompletedNCT02363478Early Phase 1Results posted
• Early Treatment of Borderline Pulmonary Arterial Hypertension Associated With Systemic Sclerosis (SSc-APAH)CompletedNCT02290613Phase 2Results posted
• Efficacy and Safety of Riociguat in Patients With Systemic SclerosisCompletedNCT02283762Phase 2Results posted
• Efficacy of Botulinum Toxin In Scleroderma-Associated Raynaud's SyndromeCompletedNCT02165111Phase 3Results posted
• A Study of Subcutaneous Abatacept to Treat Diffuse Cutaneous Systemic SclerosisCompletedNCT02161406Phase 2Results posted
• Scleroderma ARFI Imaging of the SkinCompletedNCT02006420Results posted
• Safety and Tolerability of Pirfenidone in Participants With Systemic Sclerosis-Related Interstitial Lung Disease (SSc-ILD) (LOTUSS)CompletedNCT01933334Phase 2Results posted
• Gastroesophageal Reflux Treatment in SclerodermaCompletedNCT01878526Phase 3Results posted
• Belimumab for the Treatment of Diffuse Cutaneous Systemic SclerosisCompletedNCT01670565Phase 2Results posted
• Study of Pomalidomide (CC-4047) to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Effectiveness for Patients With Systemic Sclerosis With Interstitial Lung DiseaseTerminatedNCT01559129Phase 2Results posted
• IL1-TRAP, Rilonacept, in Systemic SclerosisCompletedNCT01538719Phase 1/2Results posted
• A Study of RoActemra/Actemra (Tocilizumab) Versus Placebo in Patients With Systemic SclerosisCompletedNCT01532869Phase 3Results posted
• Macitentan for the Treatment of Digital Ulcers in Systemic Sclerosis PatientsTerminatedNCT01474122Phase 3Results posted
• Macitentan for the Treatment of Digital Ulcers in Systemic Sclerosis PatientsCompletedNCT01474109Phase 3Results posted
• Autologous Stem Cell Systemic Sclerosis Immune Suppression TrialTerminatedNCT01445821Phase 3Results posted
• Scleroderma Treatment With Autologous Transplant (STAT) StudyCompletedNCT01413100Phase 2Results posted
• Effect of Sildenafil on the Microcirculatory Blood Flow and Endothelial Progenitor Cells in Systemic SclerosisCompletedNCT01347008Phase 3Results posted
• Imatinib and Rituximab in Treating Cutaneous Sclerosis in Patients With Chronic Graft-Versus-Host DiseaseCompletedNCT01309997Phase 2Results posted
• Nilotinib in the Treatment of Systemic SclerosisCompletedNCT01166139Phase 2Results posted
• Study of Ambrisentan With Antifibrotic Agent Combination Therapy in Diffuse Systemic SclerosisCompletedNCT01093885Not applicableResults posted
• Rituximab for Treatment of Systemic Sclerosis-Associated Pulmonary Arterial Hypertension (SSc-PAH)CompletedNCT01086540Phase 2Results posted
• Exercise Induced Pulmonary Hypertension in Systemic Sclerosis and Treatment With AmbrisentanCompletedNCT01051960Phase 4Results posted
• A Clinical Trial of Ambrisentan and Tadalafil in Pulmonary Arterial Hypertension Associated With Systemic SclerosisCompletedNCT01042158Phase 4Results posted
• Comparison of Therapeutic Regimens for Scleroderma Interstitial Lung Disease (The Scleroderma Lung Study II)CompletedNCT00883129Phase 2Results posted
• Open-Label Study of Oral Treprostinil in Digital UlcersTerminatedNCT00848107Phase 2Results posted
• Digital Ischemic Lesions in Scleroderma Treated With Oral Treprostinil DiethanolamineCompletedNCT00775463Phase 2Results posted
• Safety Evaluation of Dasatinib in Subjects With Scleroderma Pulmonary FibrosisCompletedNCT00764309Phase 1/2Results posted
• A Study to Evaluate the Efficacy of an Oral Medication in the Treatment and Prevention of Digital Ulcers in Patients With Systemic Sclerosis (Scleroderma).CompletedNCT00725361Not applicableResults posted
• Reduced Intensity Transplant in Medically Refractory Systemic Lupus Erythematosus (SLE) and Systemic Sclerosis (SSc)TerminatedNCT00684255Phase 1Results posted
• Allogeneic Hematopoietic Cell Transplantation for Severe Systemic SclerosisCompletedNCT00622895Phase 1/2Results posted
• Efficacy and Tolerability of STI571 (Imatinib Mesylate) for the Treatment of Fibrosis in Participants With Systemic SclerosisCompletedNCT00613171Phase 2Results posted
• Imatinib Mesylate (Gleevec) in the Treatment of Systemic SclerosisCompletedNCT00555581Phase 2Results posted
• A Study Using The Experimental Drug Called Imatinib (Gleevec) in Subjects With Systemic SclerosisCompletedNCT00512902Phase 1/2Results posted
• Imatinib in Systemic SclerosisCompletedNCT00506831Phase 1/2Results posted
• High Dose Cyclophosphamide for Treatment of SclerodermaCompletedNCT00501995Phase 3Results posted
• A Rho-kinase Inhibitor (Fasudil) in the Treatment of Raynaud's PhenomenonCompletedNCT00498615Phase 3Results posted
• A Study to Evaluate the Safety and Efficacy of Abatacept in Patients With Diffuse Systemic Sclerosis (Scleroderma)CompletedNCT00442611Phase 1/2Results posted
• Placebo Controlled Trial of Bosentan in Scleroderma PatientsTerminatedNCT00377455Phase 2Results posted
• Pulmonary Involvement in Scleroderma: A Clinical Study of the Safety and Efficacy of Mycophenolate Mofetil in Scleroderma Patients With Lung InvolvementCompletedNCT00333437Not applicableResults posted
• Cyclophosphamide and rATG With Hematopoietic Stem Cell Support in Systemic SclerodermaCompletedNCT00278525Phase 2Results posted

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