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Not yet recruitingNCT06292572Updated Mar 5, 2024

Clinical Characteristics and Surgical Outcomes of the Fellow Eye in Bilateral Retinal Detachments

An observational study in Retinal Detachment, sponsored by Central Hospital, Nancy, France. Not yet recruiting at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2024-03-05.

Sponsored by Central Hospital, Nancy, France · Observational

From the registry’s dates

  • Primary completion was expected by Nov 2024, 2 years ago, but the record still lists the study as not yet recruiting.
Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
25
Ages
18 Years and older
Sex
All
01

Study summary

To assess the clinical features and the surgical outcomes of RD repair surgery of the fellow eye in bilateral retinal detachments

Read the detailed description

Bilateral retinal detachment is a rare but sight-threatening disease, that can cause blindness and poor quality of life.

It has been proved that patients who suffer from RD in one eye have a considerably increased risk to subsequently develop an RD in the fellow eye.

It can be expected that patients who experienced a RD in one eye, tend to present sooner when experiencing a RD in the fellow eye, and thus have a greater visual and/or anatomical prognosis.

In this study, we aim to describe characteristics of bilateral RD and compare the initial and subsequent eye in terms of clinical preoperative features, surgical management, and anatomical and visual results.

02

Conditions studied

  • Retinal Detachment

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Keywords

  • retinal detachment
  • bilateral
  • vitrectomy
03

In context

Retinal Detachment

199 studies on the registry are indexed under Retinal Detachment; 29 are open to participants now.

This study's planned enrollment of 25 is below the median of 60 across 58 observational studies indexed under Retinal Detachment.

Browse Retinal Detachment studies →

Lead sponsor

Central Hospital, Nancy, France is the lead sponsor of 798 studies on the registry; 186 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

All patients that underwent retinal detachment repair surgery for bilateral sequentiel retinal detachment between January 2016 and December 2023 at the Nancy Regional and University Hospital Center

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • All patients that underwent retinal detachment repair surgery for bilateral sequential retinal detachment between January 2016 and December 2023 at the Nancy Regional and University Hospital Center (via pars plana vitrectomy or scleral buckling) and with a minimum of 6 month of post-operative follow-up after the last surgery.

Exclusion criteria

Exclusion Criteria:

  • Patients that underwent surgery at another facility
  • Patients with a history of previous vitrectomy or
  • Patients with a history of trauma from a penetrating injury or ruptured globe, retinal neovascular condition, hereditary vitreo-retinopathy
05

Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
25 participants (estimated)
Patient registry
No

Groups and cohorts

  • Initial Retinal Detachment

    First of both eyes of the same patient that underwent retinal detachment repair

    Procedure: Retinal Detachment Surgery

  • Subsequent Retinal Detachment

    Subsequent eye undergoing retinal detachment repair

    Procedure: Retinal Detachment Surgery

Interventions

  • ProcedureRetinal Detachment Surgery

    Retinal Detachment Surgery that consists in either Pars Plana Vitrectomy or Scleral Buckling or a combination of both techniques, and with or without use of intraocular tamponade

    Also known as: Pars plana Vitrectomy (PPV), Scleral Buckle (SB), PPV + SB

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What researchers measure

Primary outcomes

  1. Rate of surgical success

    Rate of succesful surgical repair of RD within the follow-up period

    Time frame: 6 month after surgery

Secondary outcomes

  1. Visual Acuity

    LogMAR Visual acuity measured at the follow-up visit

    Time frame: 6 month after surgery

07

Study locations

1 site
08

References and documents

Publications

  • Xu D, Belin PJ, Staropoli PC, Yannuzzi NA, Vangipuram G, Chiang A, Shah GK, Townsend JH, Ryan EH, Klufas MA. Clinical Outcomes in Sequential, Bilateral Rhegmatogenous Retinal Detachment: A Multicenter, Paired-Eye Analysis. Ophthalmol Retina. 2021 Aug;5(8):797-804. doi: 10.1016/j.oret.2020.11.002. Epub 2020 Nov 14. PubMed 33197679 ↗
  • Walia HS, Shah GK, Blinder KJ. Characteristics and outcomes of sequential rhegmatogenous retinal detachments. Ophthalmic Surg Lasers Imaging Retina. 2015 Apr;46(4):445-9. doi: 10.3928/23258160-20150422-07. PubMed 25970865 ↗
  • Mitry D, Singh J, Yorston D, Siddiqui MA, Murphy AL, Wright AF, Fleck BW, Campbell H, Charteris DG. The fellow eye in retinal detachment: findings from the Scottish Retinal Detachment Study. Br J Ophthalmol. 2012 Jan;96(1):110-3. doi: 10.1136/bjo.2010.194852. Epub 2011 Mar 3. PubMed 21378003 ↗
  • Radeck V, Schindler F, Helbig H, Gamulescu MA, Cvetkov Y, Barth T, Maerker D. Characteristics of Bilateral Retinal Detachment. Ophthalmologica. 2023;246(2):99-106. doi: 10.1159/000527625. Epub 2022 Oct 25. PubMed 36282053 ↗
  • Mastropasqua L, Carpineto P, Ciancaglini M, Falconio G, Gallenga PE. Treatment of retinal tears and lattice degenerations in fellow eyes in high risk patients suffering retinal detachment: a prospective study. Br J Ophthalmol. 1999 Sep;83(9):1046-9. doi: 10.1136/bjo.83.9.1046. PubMed 10460773 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 5, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT06292572
Responsible party
Professeur Jean-Baptiste CONART (MD, PhD, Central Hospital, Nancy, France) — Principal investigator
First posted
Mar 5, 2024
Start date
Mar 1, 2024 (estimated)
Primary completion
Nov 1, 2024 (estimated)
Completion
Nov 1, 2024 (estimated)
Last update
Mar 5, 2024

Study contacts

Ida Gordon
Contact
gordon.ida14@gmail.com
+33622820203
Jean-Baptiste Conart, MD, PhD
Contact
jbconart@gmail.com
Jean-Baptiste Conart, MD, PhD
principal investigator · CHRU de Nancy

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Feb 2024. You cannot join it, but the record below documents what was studied.

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Discussion

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