An interventional study of Perfluorocarbon Liquid vs. Posterior Retinotomy during Pars-plana Vitrectomy for The Surgical Repair of Rhegmatogenous Retinal Detachment in Rhegmatogenous Retinal Detachment, sponsored by Benha University. Completed at 1 site in Egypt. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-04-09.
Sponsored by Benha University · Not applicable, Interventional, and Treatment
Purpose To evaluate the outcomes of perfluorocarbon liquid (PFCL) versus posterior retinotomy (PR) during Pars plana vitrectomy (PPV) for Rhegmatogenous retinal detachment (RRD), focusing on anatomical success, visual acuity, intraocular pressure (IOP), and complications.
Methods This is a prospective randomized controlled trial that included 58 eyes with RRD, divided into Group A (PFCL, n = 29) and Group B (PR, n = 29). Preoperative assessments included best-corrected visual acuity (BCVA), IOP, axial length, lens status, macula status, and PVR grade. Outcomes were evaluated at 1 week, 1 month, 2 months, and 3 months postoperatively. Primary outcomes included retinal reattachment rates and the number of operations; secondary outcomes included BCVA, IOP changes, complications like cataract development, retinal redetachment, epiretinal membrane (ERM) formation, and single-surgery success.
199 studies on the registry are indexed under Retinal Detachment; 29 are open to participants now.
This study's enrollment of 29 is below the median of 50 across 132 interventional studies indexed under Retinal Detachment.
Browse Retinal Detachment studies →Benha University is the lead sponsor of 362 studies on the registry; 66 are open to participants now.
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A clear diagnosis of primary RRD requiring surgery, 18 years or older, The potential to return for follow-up visits for at least 6 months post-surgery.
Exclusion criteria:
When presented with tractional or exudative retinal detachment, had surgery on the affected eye in the past, presented with severe eye disorders like advanced glaucoma or endophthalmitis.
Procedure: Perfluorocarbon Liquid vs. Posterior Retinotomy during Pars-plana Vitrectomy for The Surgical Repair of Rhegmatogenous Retinal Detachment
Procedure: Perfluorocarbon Liquid vs. Posterior Retinotomy during Pars-plana Vitrectomy for The Surgical Repair of Rhegmatogenous Retinal Detachment
This study compares outcomes of perfluorocarbon liquid (PFCL) versus posterior retinotomy (PR) during Pars plana vitrectomy (PPV) for Rhegmatogenous retinal detachment (RRD), focusing on anatomical success, visual acuity, intraocular pressure (IOP), and complications
Retinal reattachment rates
Time frame: One month, Two months, and Three Months
Number of operations
Time frame: One month, Two months, and Three Monthes
Best-corrected visual acuity (BCVA)
Time frame: One month, Two months, and Three Monthes
Intraocular pressure (IOP)
Time frame: One month, Two months, and Three Monthes
Complications like cataract development, retinal redetachment, epiretinal membrane (ERM) formation, and single-surgery success
Time frame: One month, Two months, and Three Monthes
Plan to share: Undecided
This study is completed, as verified in Mar 2025. You cannot join it, but the record below documents what was studied.
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