An interventional study of Application of antipruritic cream and The control group will receive an emollient cream (B), prepared by the hospital pharmacy, without antipruritic or soothing ingredients. in Pruritus, sponsored by Dolores Lopez Romero. Not yet recruiting at 1 site in Spain. Open to participants aged 6 Years to 12 Years. Per ClinicalTrials.gov, last updated 2026-11-10.
Sponsored by Dolores Lopez Romero · Not applicable, Interventional, and Treatment
Skin prick tests are among the most widely used diagnostic procedures for IgE-mediated allergic diseases, such as rhinitis, bronchial asthma, and food allergy. They are rapid, cost-effective, and sensitive techniques; however, they may cause local discomfort and itching (pruritus), which can be particularly distressing for children.
In pediatric nursing, improving patient comfort and reducing anxiety are key priorities. Various interventions, including topical corticosteroids, ice, and cold, wet compresses, have been used to relieve itching, but none has been shown to effectively reduce pruritus following skin prick testing. Available evidence suggests that post-prick test itching usually resolves spontaneously and that topical corticosteroids have not demonstrated clear superiority over simple interventions. Therefore, this study will evaluate whether applying the soothing topical cream Ceramol Beta Complex® effectively relieves itching, improves the quality of nursing care, and enhances patient well-being.Applying Ceramol Beta Complex® after skin prick test results have been read may reduce the intensity or duration of itching in children aged 6-12 years compared with a moisturizing cream without specific soothing active ingredients.To evaluate the efficacy of Ceramol Beta Complex® cream in reducing pruritus associated with positive skin prick test reactions in pediatric patients.This prospective, randomized study will include children aged 6-12 years undergoing skin prick testing in a pediatric allergy clinic. A total of 100 children will be enrolled and randomly allocated to one of two groups: (A) an intervention group, which will receive Ceramol Beta Complex® cream, or (B) a control group, which will receive the emollient cream routinely used in our pediatric allergy clinics
490 studies on the registry are indexed under Pruritus; 93 are open to participants now.
This study's planned enrollment of 100 is above the median of 60 across 422 interventional studies indexed under Pruritus.
Browse Pruritus studies →This is the only study on the registry with Dolores Lopez Romero as lead sponsor.
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Exclusion Criteria
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
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Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Corticosteroids (steroids)
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Emollient cream application
Other: The control group will receive an emollient cream (B), prepared by the hospital pharmacy, without antipruritic or soothing ingredients.
Emollient Cream( SOC)
Other: Application of antipruritic cream
Application of antipruritic cream after skin prick test readings.
Apply a small amount of emollient cream after skin prick testing.
Effect of Ceramol Beta Complex® on Pruritus in Pediatric Patient
Evaluation of Pruritus Score Changes Following Ceramol Beta Complex® Treatment in Pediatric Patients with Positive Skin Prick Tests: A Controlled Study
Time frame: Reduction in Itching from Cream Application to 30 Minutes Post-Application
Pruritus Intensity: Ceramol Beta Complex® vs. Emollient at T0 and T5
To compare pruritus intensity following the application of Ceramol Beta Complex® versus a standard emollient cream without active soothing ingredients, routinely used in the Pediatric Allergy Clinic after skin prick testing.
Time frame: at T0 (before cream application) and T5 (5 minutes after application).
Pruritus Reduction: Ceramol Versus Standard Moisturizer
To determine whether the application of Ceramol Beta Complex® produces a reduction of ≥2 points on the pruritus scale compared with the standard moisturizer routinely used
Time frame: 30 Minutes Post-Application
Plan to share: No — It's not necessary
Start is estimated for Nov 2026; primary completion for Jun 2027, 7 months later.
Of 85 non-industry interventional studies with no phase under Pruritus, half reached primary completion within 7 months of starting (the median), counting those still running; a quarter within 4 and three quarters within 14. This study's planned 7 months is close to that.
Counting every sponsor, half of 101 studies reached it within 7 months; a quarter within 3 and three quarters within 13.
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
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