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RecruitingNCT07442396Updated Mar 3, 2026

The Effectiveness of Exercise in the Treatment of Erectile Dysfunction and Premature Ejaculation

An interventional study of control and exercise in Erectile Dysfunction and Premature Ejaculation, sponsored by Uskudar University. Recruiting at 1 site in Turkey (Türkiye). Open to male participants aged 25 Years to 45 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-03-03.

Sponsored by Uskudar University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Primary completion was expected by May 2026, 5 months ago, but the record still lists the study as recruiting.
  • Started Mar 2026; still recruiting 8 months later.
Phase
Not applicable
Study type
Interventional
Enrollment
50
Allocation
Randomized
Ages
25 Years to 45 Years
Sex
Male
01

Study summary

The aim is to investigate the effectiveness of exercise in the treatment of erectile dysfunction and premature ejaculation.

Read the detailed description

The study was designed as a randomized controlled trial. Participants were divided into two equal groups: a control group and an exercise group. Patients in the control group were followed with normal conventional medical treatment, while participants in the exercise group underwent an 8-week, 3-day-a-week exercise program. All participants were evaluated before and after treatment using the Index of Erectile Function, the World Health Organization Quality of Life Short Form, and the Premature Ejaculation Diagnostic Tool.

02

Conditions studied

  • Erectile Dysfunction
  • Premature Ejaculation
03

In context

Erectile Dysfunction

701 studies on the registry are indexed under Erectile Dysfunction; 125 are open to participants now.

This study's planned enrollment of 50 is below the median of 70 across 551 interventional studies indexed under Erectile Dysfunction.

Browse Erectile Dysfunction studies →

Lead sponsor

Uskudar University is the lead sponsor of 170 studies on the registry; 36 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
25 Years to 45 Years
Sexes eligible
Male
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Male individuals aged 25-45 years
  • Individuals diagnosed with erectile dysfunction and premature ejaculation
  • Individuals who voluntarily agree to participate in the study and sign the form
  • Individuals who have the physical and cognitive capacity to participate in pelvic floor physiotherapy applications

Exclusion criteria

Exclusion Criteria

  • Individuals with a history of surgery in the pelvic region
  • Individuals with a diagnosis of neurological disease or neurological disorder that may affect pelvic floor muscle function
  • Presence of active infection, inflammation, or painful pathology in the pelvic region
  • Individuals who regularly use medications that significantly affect sexual function
  • Individuals with serious psychiatric illness or cognitive impairment that may hinder study compliance
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Informed consent

Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.

You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
50 participants (estimated)

Study arms

  • Active comparator
    control group

    only patients who receive medical treatment and informational training

    Other: control

  • Experimental
    exercise group

    Patients who receive pelvic floor exercises in addition to medical treatment and education.

    Other: exercise

Interventions

  • Othercontrol

    Patients in the control group will be followed with normal conventional medical treatment.

    Also known as: medical treatment

  • Otherexercise

    Participants in the exercise group will undergo an 8-week, 3-day-a-week exercise program.

    Also known as: Pelvic Floor Exercise Group

06

What researchers measure

Primary outcomes

  1. International Index of Erectile Dysfunction

    Mean change in International Index of Erectile Dysfunction scores. There are five specific areas addressed including Erectile Function (questions:1-5 \& 15;score range: 0-5, maximum score:30); Orgasmic Function (questions:9-10; score range:0-5; maximum score:10); Sexual desire (questions:11-12; score range:1-5; maximum score:10); Intercourse satisfaction (questions:6-8; score range:0-5; maximum score:15); Overall satisfaction (questions:13-14; score range:1-5; maximum score:10). The lower the score represents greater dysfunction within each domain.

    Time frame: 10 weeks

  2. Premature Ejaculation Diagnostic Tool

    it was developed by Symonds et al. (2007) to better define premature ejaculation for use in clinical studies, this is a 5-point Likert-type scale consisting of 5 items. The scale was adapted to Turkish by Serefoglu et al. (2009). The highest score that can be obtained from the scale is 20.0 and the lowest score is 0.0. Scores higher than 11 are defined as "Premature Ejaculation", scores of 9-10 are defined as "possible Premature Ejaculation", and scores of eight or less are defined as "no Premature Ejaculation".

    Time frame: 10 weeks

07

Study locations

1 of 1 sites recruiting
08

References and documents

Publications

  • Yaacov D, Nelinger G, Kalichman L. The Effect of Pelvic Floor Rehabilitation on Males with Sexual Dysfunction: A Narrative Review. Sex Med Rev. 2022 Jan;10(1):162-167. doi: 10.1016/j.sxmr.2021.02.001. Epub 2021 Apr 27. PubMed 33931383 ↗
  • Sahin E, Brand A, Cetindag EN, Messelink B, Yosmaoglu HB. Pelvic physical therapy for male sexual disorders: a narrative review. Int J Impot Res. 2025 Dec;37(12):941-949. doi: 10.1038/s41443-025-01034-5. Epub 2025 Feb 27. PubMed 40016382 ↗
  • Niu C, Ventus D, Wen G, Santtila P. Associations between self-reports of physical activity, interoceptive awareness, autonomic regulation, premature ejaculation, and erectile dysfunction in Chinese men. Int J Impot Res. 2025 Dec;37(12):992-1001. doi: 10.1038/s41443-025-01072-z. Epub 2025 Apr 19. PubMed 40251377 ↗

Individual participant data

Plan to share: No

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 3, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07442396
Lead sponsor
Uskudar University
Responsible party
Doç.Dr.Ömer Şevgin (Assoc.Prof.Dr., Uskudar University) — Principal investigator
First posted
Mar 2, 2026
Start date
Mar 1, 2026
Primary completion
May 30, 2026 (estimated)
Completion
Jul 10, 2026 (estimated)
Last update
Mar 3, 2026

Study contacts

Ömer ŞEVGİN
Contact
omer.sevgin@uskudar.edu.tr
+905069787535
Parsa Keihani
study chair · Uskudar University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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