Pouchitis clinical trials
The registry lists 50 studies for Pouchitis across more than 10 countries. 12 are recruiting or about to start. 37 of them are mainly about Pouchitis (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-29.
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Who runs them
University of North Carolina, Chapel Hill (4) · Tel-Aviv Sourasky Medical Center (3) · Ole Thorlacius-Ussing, MD, DMSc, Professor of Surgery (2) · Mayo Clinic (2) · Ocera Therapeutics (2) · Maia Kayal (2) · Charite University, Berlin, Germany (2) · Jinling Hospital, China (2)
What is being tested here
Drugs under test in Pouchitis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 5
- Apr 2027Exploring the Influence of Trptophan on the Treatment of Pouchitis · Universitätsklinikum Hamburg-Eppendorf
- May 2027Study of EXE-346 Live Biotherapeutic to Reduce High Bowel Movement Frequency in Subjects With an IPAA (PROF) · Exegi Pharma, LLC
- Jun 2027Fecal Microbiota Transplant for Patients With Chronic Pouchitis · Maia Kayal
- Jul 2027Rifaximin for the Secondary Prevention of Recurrent Pouchitis · University of North Carolina, Chapel Hill
- Oct 2027Mirikizumab in the Treatment of Chronic Inflammatory Conditions of the Pouch · University of North Carolina, Chapel Hill
Who these studies take
Of the 8 Pouchitis studies recruiting now, 3 (38%) set no upper age limit and 4 (50%) stop at 75 or younger. 1 (13%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (13%) | 1 (13%) |
| 18 | 7 (88%) | 7 (88%) |
| 30 | 7 (88%) | 7 (88%) |
| 40 | 7 (88%) | 7 (88%) |
| 50 | 7 (88%) | 7 (88%) |
| 65 | 7 (88%) | 7 (88%) |
| 75 | 5 (63%) | 5 (63%) |
| 85 | 3 (38%) | 3 (38%) |
Across all 50 studies, recruiting or not: 38% stop at 75 or younger and 12% at 65; 8% take children; 0% are for women only and 0% for men only; 8% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 11, 2026.
Newly registered1
- Oral Aeromonas sp. MTB Phage Therapy for Pouchitis in Patients With Ulcerative Colitis (UC)Oct 16, 2026NCT07878026
Studies
Recruiting first, then most recently updated. Showing 50 of 50. search them.
- Rifaximin for the Secondary Prevention of Recurrent PouchitisRecruitingNCT06312683Phase 41 country
- Oral Aeromonas sp. MTB Phage Therapy for Pouchitis in Patients With Ulcerative Colitis (UC)Not yet recruitingNCT07878026Early Phase 11 country
- Etrasimod as Prevention of PouchitisRecruitingNCT07486921Phase 21 country
- Emerging Indications for Hyperbaric Oxygen TreatmentNot yet recruitingNCT07240649Phase 4
- ASAPP Study - Topical 5-ASA as Prophylaxis for Pouchitis in Ulcerative Colitis Patients After Pelvic Pouch SurgeryNot yet recruitingNCT07773948Phase 41 country
- Fecal Microbiota Transplant for Patients With Chronic PouchitisRecruitingNCT05829109Early Phase 11 country
- A Study to Learn About the Safety of Vedolizumab and How Well it Works in Children and Teenagers With Active Chronic PouchitisRecruitingNCT06443502Phase 38 countries
- Study of EXE-346 Live Biotherapeutic to Reduce High Bowel Movement Frequency in Subjects With an IPAA (PROF)RecruitingNCT05938465Phase 1/21 country
- GUselkumAb inteRvention and DIet evaluAtioN for PouchitisRecruitingNCT06916390Phase 41 country
- Exploring the Influence of Trptophan on the Treatment of PouchitisNot yet recruitingNCT06861140Not applicable
- Inflammatory Bowel Diseases Remission RegistryRecruitingNCT049129991 country
- Advanced Therapy Registry of IBD PatientsRecruitingNCT049980841 country
- Mirikizumab in the Treatment of Chronic Inflammatory Conditions of the PouchActive, not recruitingNCT06864403Phase 41 country
- Fecal Microbiota Transplantation for PouchitisCompletedNCT03545386Phase 21 country
- Intestinal Ultrasound for the Evaluation of Pouchitis and Other Outcomes After Ileal Pouch-Anal AnastomosisCompletedNCT06316999Not applicable1 country
- CLF065 for Chronic PouchitisSuspendedNCT07226050Phase 21 country
- Stem Cells for the Treatment of PouchitisWithdrawnNCT05578508Phase 11 country
- The Role of Secondary Bile Acids in Intestinal InflammationTerminatedNCT03724175Phase 2/31 country
- the Prophylaxis of Recurrent Pouchitis After Fecal Microbiota Transplant in UC With Ileo-anal AnastomosisActive, not recruitingNCT03524352Phase 31 country
- Stelara fOr ChRonic AntibioTic rEfractory pouchitiSCompletedNCT04089345Phase 31 country
- Efficacy of Liraglutide Therapy in Patients With IPAATerminatedNCT04763564Phase 21 country
- Tofacitinib For Treatment Of Chronic PouchitisTerminatedNCT04580277Phase 21 country
- Assessment of Patients With Acute Pouchitis Treated With AntibioticsSuspendedNCT052522733 countries
- Treating Chronic Pouchitis With a Low FODMAP DietWithdrawnNCT04640155Not applicable1 country
- GM-CSF, Fosfomycin and Metronidazole for Pouchitis in Ulcerative Colitis Patients After Restorative IPAA SurgeryStatus unknownNCT04979832Phase 1/21 country
- Clotrimazole Enemas for Pouchitis in Children and AdultsTerminatedNCT00061282Phase 1/21 country
- Inflammatory Bowel Diseases (IBD) Cannabis RegistryStatus unknownNCT055783131 country
- Study of the Safety and Efficacy of AMT-101 in Subjects With PouchitisCompletedNCT04741087Phase 210 countries
- Faecal Microbiota Transplantation in the Treatment of Chronic PouchitisTerminatedNCT04100291Not applicable1 country
- Faecal Microbiota Transplantation From Normal Pouch Function Donor in the Treatment of Chronic PouchitisCompletedNCT04820413Not applicable1 country
- A Study to Evaluate the Efficacy and Safety of Vedolizumab in the Treatment of Chronic PouchitisCompletedNCT02790138Phase 49 countries
- Prospective Dietary Therapy Using Crohn's Disease Exclusion Diet for Ileal Pouch Anal Anastomosis PatientsStatus unknownNCT04327219Not applicable1 country
- Fecal Microbiota Transplantation (FMT) in the Treatment of PouchitisCompletedNCT03378921Phase 21 country
- Objective Perfusion Rate Assessment by Near-infrared Fluorescence in Ileal Pouch Formation and Ileal-pouch-anal AnastomosisStatus unknownNCT04695964Not applicable1 country
- Subjective Near-infrared Fluorescence Guidance in Perfusion Assessment of Ileal Pouch Formation and Ileal-pouch-anal AnastomosisStatus unknownNCT04695184Not applicable1 country
- Efficacy of Alicaforsen in Pouchitis Patients Who Have Failed to Respond to at Least One Course of AntibioticsCompletedNCT02525523Phase 310 countries
- Study of Sc-FOS for Pouchitis PreventionCompletedNCT02203955Phase 11 country
- Fecal Microbiota Transplantation for Chronic PouchitisCompletedNCT03538366Not applicable1 country
- Safety and Efficacy of Fecal Microbiome Transplantation (FMT) in the Treatment of Antibiotic Dependent Pouchitis (ADP)TerminatedNCT02782325Phase 1/21 country
- Fecal Microbiota Transplant (FMT) for PouchitisCompletedNCT02428361Early Phase 11 country
- Nutritional Impact of Serum-Derived Bovine Immunoglobulin Protein Isolate in Subjects With IPAACompletedNCT02828410Not applicable1 country
- Hyperbaric Oxygen Therapy for Antibiotic Refractory PouchitisStatus unknownNCT03526796Not applicable1 country
- Microbiota and Immune microEnvironment in PouchitisStatus unknownNCT03136419Not applicable1 country
- To Determine the Effect of Honey Enema in the Treatment of Patients With Acute PouchitisCompletedNCT02201186Phase 21 country
- Surgical Reconstruction in Ulcerative Colitis With Primary Sclerosing CholangitisCompletedNCT017989531 country
- Adalimumab in the Treatment of Chronic PouchitisCompletedNCT01670240Phase 31 country
- Safety and Efficacy of AST-120 in the Treatment of Antibiotic-Refractory PouchitisTerminatedNCT00583531Phase 21 country
- Safety and Efficacy of AST-120 in the Treatment of PouchitisCompletedNCT00583076Phase 21 country
- The Interaction Between Intestinal Microbiota, Innate Defense and Epithelial Integrity in the Development of PouchitisStatus unknownNCT012023961 country
- Clinical Approaches to Ileal Pouch DysfunctionCompletedNCT00293553Phase 31 country