SupplementDrug
Tryptophan clinical trials
- studies test it
- 20
- open now
- 4
- in phase 3
- 4
- first study started
- 1997
Keep track of what changes. Save the Tryptophan studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Combined with it in one product
Studies by the year they started
20 studies that test it; most in 2014 (4)
| Year | Studies |
|---|---|
| 1997 | 1 |
| 2001 | 1 |
| 2010 | 1 |
| 2011 | 1 |
| 2012 | 2 |
| 2013 | 1 |
| 2014 | 4 |
| 2015 | 2 |
| 2016 | 1 |
| 2017 | 1 |
| 2019 | 1 |
| 2022 | 1 |
| 2023 | 2 |
| 2025 | 1 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 2
- 5
- Phase 3
- 4
- Phase 4
- 2
- No phase
- 9
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 4 · Other 16
Dr. F. Köhler Chemie GmbH (4) · McMaster University (2) · University Hospital, Basel, Switzerland (2) · University of Maryland, Baltimore (1) · Scientific Institute San Raffaele (1) · The Hospital for Sick Children (1) · National Institute on Drug Abuse (NIDA) (1) · Fundació Sant Joan de Déu (1)
Often tested with
Tested in the same studies.
Histidine (6) · Ketoglutaric Acids (6) · Mannitol (6) · Sodium Chloride (6) · Potassium Chloride (6) · Magnesium Chloride (6) · Calcium Chloride (6) · Custodiol-N solution (4)
Studies
Open first, then newest update. How each study uses Tryptophan is read from its arms, and is right about nine times in ten.
Testing it · 20
- Study of Organ Perfusion in Heart Transplantation in ChildrenRecruitingPhase 2Dr. F. Köhler Chemie GmbHNCT06032195Written as Custodiol
- Exploring the Influence of Trptophan on the Treatment of PouchitisNot yet recruitingNot applicableUniversitätsklinikum Hamburg-EppendorfNCT06861140Written as Tryptophan 25mg/kg bodyweight
- Tryptophan for Impaired AhR Signaling in Celiac DiseaseRecruitingNot applicableMcMaster UniversityNCT05576038Written as L-Tryptophan
- A Nutritional Intervention to Prevent Stress Induced Intestinal Hyper-PermeabilityRecruitingNot applicableKU LeuvenNCT06089811Written as L-Tryptophan
- Tryptophan MRI in People With Schizophrenia and Healthy ControlsCompletedPhase 2/3University of Maryland, BaltimoreNCT02067975Written as Tryptophan
- The Role of Dietary Tryptophan on Aryl Hydrocarbon Receptor ActivationCompletedNot applicableMcMaster UniversityNCT03059862Written as L-tryptophan
- Pilot Study: Combining Nutritional Supplements With Standard Antidepressant to Treat Depression.WithdrawnNot applicableJohn D. Dingell VA Medical CenterNCT02223299Written as L-Tryptophan
- Phase III Study Comparing Two Methods of Cardioplegia in Aortic Valve Surgery Custodiol-N Versus CustodiolCompletedPhase 3Dr. F. Köhler Chemie GmbHNCT02098772Written as Custodiol
- Study of Organ Perfusion With Custodiol-N Solution Compared With Custodiol Solution in Heart TransplantationCompletedPhase 3Dr. F. Köhler Chemie GmbHNCT02869022Written as Custodiol
- Effect of the Quality of Dietary Proteins on the Sleep Young Elite Athletes and the Obese AdolescentStatus unknownNot applicableUniversity Hospital, Clermont-FerrandNCT04041934Written as tryptophan
- CUstodiol Versus RInger: whaT Is the Best Agent?CompletedPhase 4Scientific Institute San RaffaeleNCT02327611Written as Custodiol
- Tryptophan Requirement of Healthy School Age ChildrenCompletedNot applicableThe Hospital for Sick ChildrenNCT02018588Written as tryptophan
- Effect of Amino Acids and Sugar Alcohols on Satiation Peptides and Activation of Specific Brain RegionsCompletedNot applicableUniversity Hospital, Basel, SwitzerlandNCT02823249Written as 1.56 g L-Tryptophan
- Tryptophan and Behavior Therapy for Cocaine Abuse - 1CompletedPhase 2National Institute on Drug Abuse (NIDA)NCT00000324Written as Tryptophan
- A Phase II, Randomized, Double-blind, Placebo-controlled, in Parallel Groups Clinical Trial to Assess the Safety and Efficacy of Dietary Supplementation With Tryptophan to Achieve Weight Loss, and Its Neuropsychological Effects in Adolescents With ObesityCompletedPhase 2Fundació Sant Joan de DéuNCT02612259Written as TRYPTOPHAN
- Effect of Amino Acids and Sugar Alcohols on Gastric Emptying and Release of Satiation Peptides in HumansCompletedNot applicableUniversity Hospital, Basel, SwitzerlandNCT02563847Written as 0.52 g L-Tryptophan
- Serotonin and Everyday Social InteractionCompletedEarly Phase 1University of GroningenNCT02051569Written as Tryptophan
- Phase III Study Comparing Two Methods of Cardioplegia in Coronary Artery Bypass SurgeryCompletedPhase 2Dr. F. Köhler Chemie GmbHNCT01444235Written as Custodiol
- Comparing the Protective Effects of Two Cardioplegic Solutions, on Cardiac Metabolism, as Assessed Using MicrodialysisCompletedPhase 3Centre Hospitalier Universitaire de Saint EtienneNCT01401140Written as Custodiol
- Double Blind Study of Trp01 in Patients With Alzheimer's DiseaseCompletedPhase 4Queen's UniversityNCT00202124Written as Tryptophan
Given in every arm · 1 — Tryptophan is usual care beside what is tested
Codes
What other systems call Tryptophan · ClinicalTrials.gg INT008373
- MeSH (NLM) D014364TryptophanConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 8DUH1N11BXTRYPTOPHANConfirmed FDA, NLM, Wikidata
- RxNorm 10898Confirmed FDA, Wikidata
- Wikidata Q106345470L-tryptophan zwitterionConfirmed FDA, NLM, Wikidata
- Wikidata Q181003tryptophanConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C29603TryptophanConfirmed FDA, Wikidata
- DrugBank DB00150One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D014364 | Tryptophan | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 8DUH1N11BX | TRYPTOPHAN | Confirmed FDA, NLM, Wikidata |
| RxNorm | 10898 | — | Confirmed FDA, Wikidata |
| Wikidata | Q106345470 | L-tryptophan zwitterion | Confirmed FDA, NLM, Wikidata |
| Wikidata | Q181003 | tryptophan | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C29603 | Tryptophan | Confirmed FDA, Wikidata |
| DrugBank | DB00150 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.