National Institute of Allergy and Infectious Diseases (NIAID): Pneumonia trials

The registry lists 39 Pneumonia studies with National Institute of Allergy and Infectious Diseases (NIAID) as lead sponsor. 1 are open to participants now and 2 have results posted.

Phase 1 7Phase 2 4Phase 3 16Phase 4 3No phase 9(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES)RecruitingNCT00006150
• Trial to Evaluate Beta-Lactam Antimicrobial Therapy of Community Acquired Pneumonia in ChildrenCompletedNCT02891915Phase 4Results posted
• Efficacy Study of Fluconazole to Treat Coccidioidomycosis Pneumonia (Valley Fever)TerminatedNCT02663674Phase 4Results posted
• An Observational Study to Assess the Prevalence and Outcomes of Primary Pulmonary Coccidioidomycosis in Persons Aged > / = 14 Years Presenting With Community Acquired Pneumonia (CAP) in Endemic Areas (SAnds-PPC)CompletedNCT03908632
• Aerosolized and Intravenous Colistin in Healthy AdultsTerminatedNCT01863719Phase 1
• Zinc and Pneumonia ProtocolTerminatedNCT00133432Phase 3
• Ribavirin to Prevent RSV Pneumonia in Bone Marrow Transplant PatientsTerminatedNCT00031473Phase 3
• A Comparison of HIV-Infected Patients With and Without Opportunistic (AIDS-Related) InfectionCompletedNCT00005572
• Assessment of Lung Inflammation in Patients With Atopic Asthma Using Positron Emission TomographyCompletedNCT00001759
• Interferon Gamma for Drug Resistant TuberculosisCompletedNCT00001407Phase 2
• A Study of Pentamidine Plus Dapsone in the Prevention of Pneumocystis Carinii Pneumonia (PCP) in HIV-Infected Patients Who Cannot Take Trimethoprim or SulfonamidesCompletedNCT00001028Phase 3
• A Study of Pentamidine in the Prevention of Pneumocystis Carinii Pneumonia (PCP) in HIV-Infected Children Who Cannot Take Trimethoprim-SulfamethoxazoleCompletedNCT00001027Phase 1
• A Treatment Protocol for the Use of Trimetrexate With Leucovorin Rescue for AIDS Patients With Pneumocystis Carinii Pneumonia and Serious Intolerance to Approved TherapiesCompletedNCT00001016Phase 3
• Trimetrexate Plus Leucovorin Calcium Rescue Versus Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDSCompletedNCT00001014Phase 3
• Comparison of Trimetrexate Plus Leucovorin Calcium Rescue Versus Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDSCompletedNCT00001013Phase 3
• A Study of Pentamidine in the Prevention of Pneumocystis Carinii PneumoniaCompletedNCT00001003Not applicable
• A Study of Trimetrexate in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS Not Previously Treated for PCPCompletedNCT00000998Phase 1
• A Study of Three Drugs Plus Zidovudine in the Prevention of Infections in HIV-Infected PatientsCompletedNCT00000991Phase 3
• A Study of Two Forms of Pentamidine in HIV-Infected Children Who May Have Pneumocystis Carinii PneumoniaCompletedNCT00000974Phase 1
• A Study to Evaluate the Impact of Stopping Treatment for the Prevention of Pneumonia in HIV-Positive Patients Receiving Anti-HIV Drugs Who Have Increased CD4 Cell CountsCompletedNCT00000908
• A Study of WR 6026 in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in HIV-Infected PatientsCompletedNCT00000863Phase 2
• Gradual Initiation of Sulfamethoxazole/Trimethoprim as Primary Pneumocystis Carinii Pneumonia ProphylaxisCompletedNCT00000816Phase 4
• A Study to Compare Different Drugs Used to Prevent Serious Bacterial Infections in HIV-Positive ChildrenCompletedNCT00000811Phase 2
• A Randomized, Comparative Study of Daily Dapsone and Daily Atovaquone for Prophylaxis Against PCP in HIV-Infected Patients Who Are Intolerant of Trimethoprim and/or SulfonamidesCompletedNCT00000802Phase 3
• Phase I Safety and Pharmacokinetics Study of Microparticulate Atovaquone (m-Atovaquone; 566C80) in HIV-Infected and Perinatally Exposed Infants and ChildrenCompletedNCT00000773Phase 1
• A Randomized, Comparative, Prospective Study of Daily Trimethoprim / Sulfamethoxazole (TMS) and Thrice-Weekly TMS for Prophylaxis Against PCP in HIV-Infected PatientsCompletedNCT00000748Phase 3
• The Safety and Effectiveness of Methylprednisolone in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Children With AIDSWithdrawnNCT00000741Phase 3
• Escalating Multiple-Dose Safety and Tolerance of WR 6026 Hydrochloride in HIV-Infected SubjectsCompletedNCT00000740Phase 1
• Comparison of Two Dosage Regimens of Oral Dapsone for Prophylaxis of Pneumocystis Carinii Pneumonia in Pediatric HIV InfectionCompletedNCT00000739Phase 1
• Comparison of Three Treatments for Pneumocystis Pneumonia in AIDS PatientsTerminatedNCT00000730Phase 3
• A Controlled Comparative Trial of Sulfamethoxazole-Trimethoprim Versus Aerosolized Pentamidine for Secondary Prophylaxis of Pneumocystis Carinii Pneumonia in AIDS Patients Receiving Azidothymidine (AZT)CompletedNCT00000727Phase 3
• A Study of Trimetrexate With Leucovorin Rescue for AIDS Patients Who Are Refractory to Standard Therapies for Pneumocystis Carinii PneumoniaCompletedNCT00000724Phase 3
• Aerosols in the Treatment of Pneumocystis Pneumonia: A Pilot Study Quantitating the Deposition of Aerosolized Pentamidine as Delivered in ACTG 040 and Comparing Its Toxicity With Parenteral Pentamidine TherapyCompletedNCT00000722Not applicable
• The Safety and Efficacy of Clindamycin and Primaquine in the Treatment of Mild - Moderate Pneumocystis Carinii Pneumonia in Patients With AIDSCompletedNCT00000717Not applicable
• A Controlled Trial Comparing the Efficacy of Aerosolized Pentamidine and Parenteral/Oral Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia in AIDSCompletedNCT00000715Phase 3
• An Open, Prospective, Multicenter Study of Trimetrexate With Leucovorin Rescue for AIDS Patients With Pneumocystis Carinii Pneumonia (PCP) and Serious Intolerance to Approved TherapiesCompletedNCT00000714Phase 3
• Aerosols in the Treatment of Asymptomatic Pneumocystis Pneumonia: A Pilot Study Assessing the Effectiveness of Aerosolized Pentamidine as Treatment of Subclinical Pneumocystis Infection in Patients With No Clinical SymptomsCompletedNCT00000707Not applicable
• A Randomized, Double-Blind Study of 566C80 Versus Septra (Sulfamethoxazole/Trimethoprim) for the Treatment of Pneumocystis Carinii Pneumonia in AIDS PatientsCompletedNCT00000655Phase 2
• A Phase III Comparative Study of Dapsone / Trimethoprim and Clindamycin / Primaquine Versus Sulfamethoxazole / Trimethoprim in the Treatment of Mild-to-Moderate PCP in Patients With AIDSCompletedNCT00000640Phase 3