Pneumonia, Bacterial clinical trials
The registry lists 153 studies for Pneumonia, Bacterial across more than 10 countries. 27 are recruiting or about to start. 91 of them are mainly about Pneumonia, Bacterial (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-27. Counting its 2 narrower conditions too, such as Pneumonia, Pneumococcal: 214 studies, 32 open.
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Who runs them
GlaxoSmithKline (6) · Wyeth is now a wholly owned subsidiary of Pfizer (5) · Pfizer (4) · Massachusetts General Hospital (4) · Assistance Publique - Hôpitaux de Paris (3) · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (3) · Merck Sharp & Dohme LLC (3) · Cumberland Pharmaceuticals (3)
What is being tested here
Drugs under test in Pneumonia, Bacterial studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Pn-MAPS30plus | 1 | 0 | 4 |
| Amikacin | 1 | 0 | 1 |
| MP-101 | 1 | 0 | 1 |
| Methylprednisolone Hemisuccinate | 1 | 1 | 1 |
| Methylprednisolone | 1 | 1 | 1 |
| Tigecycline | 0 | 3 | 5 |
| Levofloxacin | 0 | 3 | 4 |
| Imipenem | 0 | 2 | 3 |
| Cilastatin | 0 | 2 | 3 |
| Doripenem | 0 | 1 | 3 |
Drug classes tested here Beta-lactamase inhibitors 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026Trial to Evaluate Safety and Immune Response of an Investigational Pneumococcal Vaccine in Adults Aged 50 To 64 Years · GlaxoSmithKline
- Dec 2026MP101 in Adults With Acute Pseudomonas Aeruginosa Pneumonia · MicrobiotiX Co., Ltd
- Jan 2027Urine Pneumococcal Antigen Project · Liverpool School of Tropical Medicine
- Feb 2027FBS-ASaP: Fibrobronchoscopy in ASpiration Pneumonia in the Emergency Department · Azienda Ospedaliero-Universitaria Careggi
- Feb 2027A Trial to Evaluate the Safety and Reactogenicity of an Investigational Pneumococcal Vaccine in Toddlers 12 to 15 Months of Age Receiving a Single Booster Dose · GlaxoSmithKline
- Mar 2027A Clinical Trial to Assess the Safety and PK of OMN6 in HABP or VABP Caused by Acinetobacter Baumannii Complex · Omnix Medical Ltd
- May 2027Impact of BioFire FilmArray Pneumonia Panel vs Routine Diagnostics on Antimicrobial Outcomes (DOOR-MAT) · Hospital de Clinicas de Porto Alegre
- Jul 2027Study on the Safety and Efficacy of Polymyxin E2 Methanesulfonate for Injection in the Treatment of Hospital-Acquired Bacterial Pneumonia/Ventilator-Associated Bacterial Pneumonia Caused by Carbapenem-Resistant Gram-Negative Bacteria · Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
- Jul 2027Novel Tools to Improve Management of Paediatric Community-Acquired Pneumonia - ToolCAP · Ecole Polytechnique Fédérale de Lausanne
- Aug 2027Clinical Impact of a Machine Learning Decision Support System for Empirical Antibiotic Therapy · Instituto de Investigación Sanitaria Gregorio Marañón
Who these studies take
Of the 18 Pneumonia, Bacterial studies recruiting now, 12 (67%) set no upper age limit and 2 (11%) stop at 75 or younger. 2 (11%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (6%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (6%) | 1 (6%) |
| 18 | 15 (83%) | 15 (83%) |
| 30 | 16 (89%) | 16 (89%) |
| 40 | 16 (89%) | 16 (89%) |
| 50 | 16 (89%) | 16 (89%) |
| 65 | 16 (89%) | 16 (89%) |
| 75 | 16 (89%) | 16 (89%) |
| 85 | 14 (78%) | 14 (78%) |
Across all 153 studies, recruiting or not: 23% stop at 75 or younger and 18% at 65; 21% take children; 1% are for women only and 0% for men only; 11% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Pneumonia, Bacterial studies take
Of 15 phase 3 interventional studies under Pneumonia, Bacterial, half reached primary completion within 25 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 3 | 25 mo15–45 · 15 studies | — | — |
| Interventional, no phase | 24 mo17–39 · 19 studies | — | — |
| Observational | 24 mo14–49 · 22 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 153. Browse all 153 → or search them.
- Cefepime-Zidebactam Versus Ceftazidime-Avibactam With or Without Colistin for Hospital-Acquired or Ventilator-Associated Bacterial PneumoniaNot yet recruitingNCT07885891Phase 314 countries
- Novel Tools to Improve Management of Paediatric Community-Acquired Pneumonia - ToolCAPRecruitingNCT06670833Not applicable3 countries
- A Clinical Trial to Assess the Safety and PK of OMN6 in HABP or VABP Caused by Acinetobacter Baumannii ComplexRecruitingNCT06087536Phase 22 countries
- Impact of BioFire FilmArray Pneumonia Panel vs Routine Diagnostics on Antimicrobial Outcomes (DOOR-MAT)RecruitingNCT07585604Not applicable1 country
- Urine Pneumococcal Antigen ProjectRecruitingNCT071812001 country
- Study on the Safety and Efficacy of Polymyxin E2 Methanesulfonate for Injection in the Treatment of Hospital-Acquired Bacterial Pneumonia/Ventilator-Associated Bacterial Pneumonia Caused by Carbapenem-Resistant Gram-Negative BacteriaRecruitingNCT07512596Phase 21 country
- Clinical Impact of a Machine Learning Decision Support System for Empirical Antibiotic TherapyNot yet recruitingNCT07762378Not applicable
- " Study of the Benefit of Nebulized Amikacin in the Treatment of Gram-negative Bacillus Pneumonia Acquired During Mechanical Ventilation in Patients Receiving Extracorporeal Membrane Veno-arterial Oxygenation "RecruitingNCT06602557Phase 21 country
- ASK0912 Versus Polymyxin B for Injection in Adults With Hospital-Acquired or Ventilator-Associated Bacterial PneumoniaRecruitingNCT07759934Phase 21 country
- MP101 in Adults With Acute Pseudomonas Aeruginosa PneumoniaRecruitingNCT07492771Phase 11 country
- Comparative Study of Adherence to Antibiotic Therapy Among Pediatric Patients: Hospital Emergency Department vs. Primary Care CenterNot yet recruitingNCT07711756
- A Trial to Evaluate the Safety and Reactogenicity of an Investigational Pneumococcal Vaccine in Infants Receiving 3-dose Primary Dosing Series Followed by a Booster Dose at 12 to 15 Months of AgeNot yet recruitingNCT07406347Phase 1
- A Clinical Study of YK-1169 Versus Ceftazidime-Avibactam in Adults With Hospital-Acquired or Ventilator-Associated Bacterial PneumoniaNot yet recruitingNCT07634198Phase 3
- Efficacy and Safety of BV100 Plus Low Dose Polymyxin B Versus Colistin Plus High-dose Ampicillin/Sulbactam in Patients With Hospital-acquired or Ventilator-associated Bacterial Pneumonia Due to Carbapenem-resistant Acinetobacter Baumannii-calcoaceticus ComplexRecruitingNCT07326540Phase 31 country
- A Post-Marketing Study to Assess the Efficacy and Safety of Intravenous Polymyxin B and Colistin Methanesulfonate in Patients With Carbapenem-Resistant Gram-Negative Bacterial InfectionRecruitingNCT069662841 country
- A Study to Evaluate the Efficacy and Safety of Meropenem and Pralurbactam in HABP/VABPRecruitingNCT07327619Phase 31 country
- Investigation of the Effects of Oxidized Antigens on the T-Cell Response and the Epigenetic Reprogramming of Neutrophils in Lung Diseases - OXIGENE -Not yet recruitingNCT073869121 country
- Different Methods of Aerosolized Polymyxin B Inhalation for Treating Carbapenem-Resistant Gram-Negative Bacterial Pneumonia.RecruitingNCT070863911 country
- Rapid De-escalation of Anti-MRSA Therapy Guided by S. Aureus Nares Screening in Case of PneumoniaRecruitingNCT06238297Not applicable1 country
- Antimicrobial Therapeutic Drug Monitoring During Lung Transplant Perioperative PhaseNot yet recruitingNCT065836421 country
- Study of Leukocyte Immunophenotype and the Lipid Transport System as Predictive Biomarkers of Severe Bacterial InfectionsEnrolling by invitationNCT041789151 country
- Fosfomycin I.v. for Treatment of Severely Infected PatientsRecruitingNCT029799515 countries
- FBS-ASaP: Fibrobronchoscopy in ASpiration Pneumonia in the Emergency DepartmentRecruitingNCT065115831 country
- A Phase 3b Randomized, Double-blind, Multi-center Study to Compare the Safety and Efficacy of Omadacycline to Moxifloxacin for Treating Adult Subjects With CABPRecruitingNCT06162286Phase 31 country
- Diagnostic Accuracy of Pocket-size Lung Ultrasound in Pneumonia Etiology and Complications in Hospitalized ChildrenNot yet recruitingNCT06296693Not applicable
- Eravacycline Combination Therapy for MRABRecruitingNCT062828351 country
- Sphingosine-1-phosphate and PneumoniaRecruitingNCT04007328Phase 2/31 country
- Trial to Evaluate Safety and Immune Response of an Investigational Pneumococcal Vaccine in Adults Aged 50 To 64 YearsActive, not recruitingNCT07428759Phase 11 country
- A Trial of HRS-8427 in the Treatment of Adults With Bacterial PneumoniaCompletedNCT06841731Phase 21 country
- Combination vs. Monotherapy for Stenotrophomonas Maltophilia InfectionsCompletedNCT075935471 country
- A Phase 2 Study to Evaluate the Safety, Tolerability, and Immune Response of AFX3772 Vaccine in Healthy InfantsCompletedNCT05412030Phase 22 countries
- Discharge Stewardship in Children's HospitalsCompletedNCT05826873Not applicable1 country
- A Trial to Evaluate the Safety and Reactogenicity of an Investigational Pneumococcal Vaccine in Toddlers 12 to 15 Months of Age Receiving a Single Booster DoseActive, not recruitingNCT07406334Phase 11 country
- Efficacy and Safety of Faropenem in Bangladeshi Adult Patients With Community-Acquired Bacterial Pneumonia (CABP)CompletedNCT06804096Phase 41 country
- A Trial to Evaluate the Safety and Immune Response of an Investigational Pneumococcal Vaccine in Adults 50 To 64 Years of AgeCompletedNCT07105722Phase 11 country
- MASTERMIND-Pneumonia Study (Also Known as Pneumonia Direct Pilot)CompletedNCT061816691 country
- Systematic Search for Primary Immunodeficiency in Adults With InfectionsCompletedNCT02972281Not applicable1 country
- Using Probability of Community-Acquired Pneumonia to Tailor Antimicrobials Among InpatientsCompletedNCT05976581Not applicable1 country
- P3 Study to Assess Efficacy and Safety of Cefepime/Nacubactam and Aztreonam/Nacubactam Versus Best Available Therapy for Adults With Infection Due to Carbapenem Resistant EnterobacteralesCompletedNCT05905055Phase 314 countries
- Impact of a Strategy Based on Bacterial DNA Detection to Optimize Antibiotics in Patients With Hospital-acquired PneumoniaCompletedNCT03711331Not applicable1 country
- Artificial Intelligence-Based Evaluation of Chest X-Rays in Ventilator-Associated PneumoniaCompletedNCT075096971 country
- Derivation and Validation of the Risk Evaluation Score for Pneumonia Involving Resistant Entities (RESPIRE)CompletedNCT074255611 country
- Blinded Efficacy and Safety Study of CAL02 IV Plus SOC in Subjects With Severe Community-Acquired Bacterial PneumoniaActive, not recruitingNCT05776004Phase 219 countries
- Breathing Pattern Description in Pneumonia PatientsActive, not recruitingNCT072865521 country
- Imipenem/Cilastatin-XNW4107 Versus Imipenem/Cilastatin/Relebactam for Treatment of Participants With Bacterial Pneumonia (XNW4107-302, REITAB-2)CompletedNCT05204563Phase 34 countries
- Urease Breath Test for Rapid Characterization of PneumoniaCompletedNCT031007601 country
- Comparison Between the Progostic Value of the Procalcitonin and the Platelet/Total Leukocytic Count Ratio in SepsisCompletedNCT069916861 country
- Efficacy and Safety of Trimodulin (BT588) in Subjects With CAP Including COVID-19 PneumoniaTerminatedNCT05531149Phase 314 countries
- Cefepime-taniborbactam vs Meropenem in Adults With VABP or Ventilated HABPWithdrawnNCT06168734Phase 3
- Omadacycline vs. Moxifloxacin for the Treatment of Community-Acquired Bacterial PneumoniaCompletedNCT04779242Phase 38 countries