ClinicalTrials.gg
CompletedNCT01884194Updated Dec 29, 2015

Morphological Analysis of the Pineal Gland in Pediatric Retinoblastoma Patients Using Magnetic Resonance Imaging

An observational study in Retinoblastoma and Pineoblastoma, sponsored by Charite University, Berlin, Germany. Completed at 1 site in Germany. Open to participants aged 1 Day to 50 Years. Per ClinicalTrials.gov, last updated 2015-12-29.

Sponsored by Charite University, Berlin, Germany · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
80
Ages
1 Day to 50 Years
Sex
All
01

Study summary

MRI is useful for diagnosing pinealoblastoma in retinoblastoma patients

02

Conditions studied

  • Retinoblastoma
  • Pineoblastoma

Keywords

  • retinoblastoma
  • pineoblastoma
03

In context

Retinoblastoma

124 studies on the registry are indexed under Retinoblastoma; 23 are open to participants now.

This study's enrollment of 80 is below the median of 224 across 34 observational studies indexed under Retinoblastoma.

Browse Retinoblastoma studies →

Lead sponsor

Charite University, Berlin, Germany is the lead sponsor of 857 studies on the registry; 129 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
1 Day to 50 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

pediatric patients with retinoblastoma

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • diagnosis of retinoblastoma
  • brain MRI available

Exclusion criteria

Exclusion Criteria:

  • insufficient quality of brain MRI
05

Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
80 participants (actual)
Patient registry
No

Groups and cohorts

  • Retinoblastoma patients

    patients with diagnosed retinoblastoma

  • non-retinoblastoma patients

    aged matched control cohort without the diagnosis of ocular or brain tumor

06

What researchers measure

Primary outcomes

  1. Malignancy criteria of pineal gland

    size of pineal gland solid or cystic component (all at baseline)

    Time frame: clinical follow-up 1-year after baseline imaging

07

Study locations

1 site
  • Charite Hospital Berlin
    Berlin, 12200, Germany
08

References and documents

Publications

  • Pham TT, Siebert E, Asbach P, Willerding G, Erb-Eigner K. Magnetic resonance imaging based morphologic evaluation of the pineal gland for suspected pineoblastoma in retinoblastoma patients and age-matched controls. J Neurol Sci. 2015 Dec 15;359(1-2):185-92. doi: 10.1016/j.jns.2015.10.046. Epub 2015 Oct 28. PubMed 26671110 ↗
09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 29, 2015, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT01884194
Responsible party
Thi Thai Hien Pham (doctoral candidate, Charite University, Berlin, Germany) — Principal investigator
First posted
Jun 21, 2013
Start date
Nov 2013
Primary completion
Dec 2014
Completion
Feb 2015
Last update
Dec 29, 2015

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Dec 2015. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion