An observational study in Childhood Brain Tumor, sponsored by Universitätsklinikum Hamburg-Eppendorf. Recruiting at 57 sites in Germany. Per ClinicalTrials.gov, last updated 2025-12-04.
Sponsored by Universitätsklinikum Hamburg-Eppendorf · Observational
The I-HIT-MED registry registers clinical of children and adults with medulloblastoma, ependymoma, pineal tumours, or choroid plexus tumours in Germany and other countries that fulfil national ethic requirements for participation in this registry. These tumours are rare diseases, and many patients are treated outside of clinical trials. The I-HIT-MED registry allows collection of data und biological material from those patients, and provides a basis for standard treatment recommendations and counselling. It aims to improve the international cooperation and the medical knowledge in these rare diseases. Within the I-HIT-MED registry, it is a goal to maintain and improve networks for quality assurance in national groups where they are already established, and to support the implementation in national groups, where there is no quality assurance network yet.
The following patients can be included in this registry:
Children and adults with
Objectives of this registry:
To prospectively evaluate the clinical courses of patients with the eligible brain tumours, considering neuroradiological, pathological, and molecular / biological characteristics of the tumour and individual standard treatment data.
To collect biological specimens (tumour, CSF, peripheral blood) or their data to perform biological studies on
To assess the use of systems for quality assurance during diagnosis and treatment of brain tumours.
To assess long-term follow-up, quality of survival, neuropsychology, and other patient-centred research in these very rare tumour subtypes in the context of the registry or in cooperation with external collaborators.
Children and adults with
Exclusion Criteria:
Event free survival
Due to the explorative character of the registry, outcome measures are not strictly defined. We added the most common outcome measures.
Time frame: 10 years
Pattern of relapse
Time frame: 10 years
Overall survival
Time frame: 10 years
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
Contact study teamGet an email when the registry record changes — status, dates, results — or when someone posts here.
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Universitätsklinikum Hamburg-Eppendorf