Neural Tube Defects clinical trials

The registry lists 47 studies for Neural Tube Defects across more than 10 countries. 9 are recruiting or about to start. 30 of them are mainly about Neural Tube Defects (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-07. Counting its 4 narrower conditions too, such as Spinal Dysraphism: 231 studies, 59 open.

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Status

Completed: 21
Status unknown: 9
Recruiting: 6
Active, not recruiting: 4
Not yet recruiting: 3
Terminated: 3

Phase

Phase 1: 3
Phase 3: 3
Phase 2: 2

Where

United States: 23
Turkey: 6
China: 3
France: 2
India: 1
Eswatini: 1

Who runs them

Baylor College of Medicine (3) · Yuzuncu Yıl University (2) · Hydrocephalus and Neuroscience Institute (2) · Bayer (2) · University of Alabama at Birmingham (2) · USFetus (1) · Karabuk University (1) · Assiut University (1)

What is being tested here

Drugs under test in Neural Tube Defects studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

Drug	Phase 3	All
Folic Acid	0	2
Sodium Chloride	0	1
Iodine	0	1
Cytokine-induced killer cell	0	1
EE20	1	1
Levomefolic acid	1	1
Inositol	0	1
Geritol	0	1
Acetazolamide	0	1

Coming up

0phase 3 studies under way

6studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 6

Nov 2026First-Trimester Screening of Open Neural Tube Defects Using Biometrics and Maternal Serum Markers · University Hospital, Strasbourg, France
Dec 2026A Randomized Controlled Trial for Surgical Treatment of Recurrent Adult Tethered Cord Syndrome · Xuanwu Hospital, Beijing
Jan 2027Effectiveness of Electrical Pudendal Nerve Stimulation for Neurogenic Lower Urinary Tract Dysfunction in Pediatric Tethered Cord Syndrome Post-Surgery · Shanghai Institute of Acupuncture, Moxibustion and Meridian
Apr 2027Fetoscopic Repair of Isolated Fetal Spina Bifida · Johns Hopkins University
Apr 2027Folic Acid Salt Study (FISFA Zambia) · University of Alabama at Birmingham
Jun 2027Fetoscopic Robotic Open Spina Bifida Treatment · Mount Sinai Hospital, Canada

Who these studies take

Of the 6 Neural Tube Defects studies recruiting now, 4 (67%) set no upper age limit and 1 (17%) stop at 75 or younger. 1 (17%) take children under 18. 5 (83%) are for women only and 0 (0%) for men only; 1 (17%) take healthy volunteers.

Recruiting studies that take each age, of 6
Age	Women	Men
10	1 (17%)	1 (17%)
18	6 (100%)	1 (17%)
30	6 (100%)	1 (17%)
40	6 (100%)	1 (17%)
50	5 (83%)	1 (17%)
65	5 (83%)	1 (17%)
75	5 (83%)	1 (17%)
85	4 (67%)	0 (0%)

Across all 47 studies, recruiting or not: 70% stop at 75 or younger and 68% at 65; 38% take children; 62% are for women only and 0% for men only; 43% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

Studies

Recruiting first, then most recently updated. Showing 47 of 47. search them.