Meningomyelocele clinical trials
The registry lists 58 studies for Meningomyelocele across more than 10 countries. 14 are recruiting or about to start. 28 of them are mainly about Meningomyelocele (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06.
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Who runs them
The University of Texas Health Science Center, Houston (4) · Baylor College of Medicine (3) · University Children's Hospital, Zurich (3) · Assistance Publique - Hôpitaux de Paris (3) · Assiut University (3) · Mayo Clinic (2) · St. Louis University (2) · University Hospital, Lille (1)
What is being tested here
Drugs under test in Meningomyelocele studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 2
- Mar 2027Cellular Therapy for In Utero Repair of Myelomeningocele - The CuRe Trial · University of California, Davis
- Apr 2027Fetoscopic Repair of Isolated Fetal Spina Bifida · Johns Hopkins University
Who these studies take
Of the 11 Meningomyelocele studies recruiting now, 5 (45%) set no upper age limit and 6 (55%) stop at 75 or younger. 6 (55%) take children under 18. 3 (27%) are for women only and 0 (0%) for men only; 2 (18%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 4 (36%) | 4 (36%) |
| 18 | 7 (64%) | 4 (36%) |
| 30 | 6 (55%) | 3 (27%) |
| 40 | 6 (55%) | 3 (27%) |
| 50 | 6 (55%) | 3 (27%) |
| 65 | 6 (55%) | 3 (27%) |
| 75 | 5 (45%) | 2 (18%) |
| 85 | 5 (45%) | 2 (18%) |
Across all 58 studies, recruiting or not: 69% stop at 75 or younger and 69% at 65; 59% take children; 34% are for women only and 0% for men only; 22% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Meningomyelocele studies take
Of 25 interventional studies with no phase under Meningomyelocele, half reached primary completion within 52 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 52 mo32–84 · 25 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 58. Browse all 58 → or search them.
- Transcutaneous Spinal Stimulation for Children and Youth With Spina BifidaRecruitingNCT06918119Not applicable1 country
- Autologous Human Umbilical Cord Tissue Patch for Postnatal Closure of Open Neural Tube DefectsRecruitingNCT06929572Not applicable1 country
- tSCS in Children With Spina BifidaRecruitingNCT07615686Not applicable1 country
- Ready, Set, Go! A Physical Fitness Intervention for Children With Mobility ChallengesEnrolling by invitationNCT04789746Not applicable1 country
- Open-label, Long-term Safety, Efficacy, and Pharmacokinetics Study of Vibegron in Pediatric Subjects 2 Years to < 18 Years of Age With NDO and on CICRecruitingNCT05491525Phase 2/316 countries
- Cellular Therapy for In Utero Repair of Myelomeningocele - The CuRe TrialRecruitingNCT04652908Phase 1/21 country
- Safety and Efficacy of Devices Used in Fetoscopic Neural Tube Defect Repair CasesRecruitingNCT05672849Not applicable1 country
- Cryopreserved Human Umbilical Cord as a Meningeal Patch in Fetoscopic Spina Bifida RepairRecruitingNCT06042140Not applicable1 country
- In Utero Surgery for Fetal Myelomeningocele: Decision-making Mechanisms and Psychological Impact of Prenatal TherapyRecruitingNCT06796972Not applicable1 country
- The Role of CSF in Chiari II Brain MalformationNot yet recruitingNCT06560788
- Fetal Surgery Interview Study: Parental Perceptions of Fetal SurgeryRecruitingNCT03788122Not applicable2 countries
- Role of Perforator Flaps in Back Defects ReconstructionNot yet recruitingNCT06405698Not applicable
- Outcomes of Proactive Management of Children With MyelomeningoceleRecruitingNCT063018021 country
- Laparotomy Versus Percutaneous Endoscopic Correction of MyelomeningoceleRecruitingNCT03856034Not applicable1 country
- Incontinence and Quality of Life in Children With Spina BifidaCompletedNCT03410667Not applicable1 country
- Patch vs. No Patch Fetoscopic Meningomyelocele Repair StudyActive, not recruitingNCT03794011Phase 11 country
- Fetoscopic NEOX Cord 1K® Spina Bifida RepairActive, not recruitingNCT04243889Not applicable1 country
- Fetoscopic Meningomyelocele Repair StudyCompletedNCT02230072Phase 11 country
- Spina Bifida Healthcare Navigator ProgramActive, not recruitingNCT07531862Not applicable1 country
- Inflammatory Response in Children Suffering From Tethered CordCompletedNCT07611058Not applicable1 country
- Sleep-disordered Breathing in Infants With MyelomeningoceleCompletedNCT042518061 country
- In-Utero Endoscopic Correction of Spina BifidaActive, not recruitingNCT04362592Not applicable1 country
- Fetoscopic Repair of Isolated Fetal Spina BifidaActive, not recruitingNCT03090633Not applicable1 country
- Operating Room Extubation and Postoperative Outcomes in Neonates With MeningomyeloceleActive, not recruitingNCT074650551 country
- Maternal-fetal Immune Responses to Fetal SurgeryCompletedNCT044844411 country
- Dual Task and Upper Extremity Performance in Children With MyelomeningoceleCompletedNCT069494751 country
- Efficacy Of Pulsed Electromagnetic Field Therapy On Neurogenic Bladder in Children With MyelomeningoceleActive, not recruitingNCT04187027Not applicable1 country
- Prenatal Endoscopic Repair of Fetal Spina BifidaCompletedNCT02390895Not applicable1 country
- Prenatal Surgical Repair of Fetal MyelomeningoceleCompletedNCT01983345Not applicable1 country
- Prenatal and Postnatal Ultrasonographic Evaluation of Myelomeningocele to Predict Post-Surgical OutcomesActive, not recruitingNCT070486911 country
- Minimally Invasive Fetoscopic Regenerative Repair of Spina Bifida - A Pilot StudyCompletedNCT03936322Not applicable1 country
- Extended Criteria For Fetal Myelomeningocele RepairCompletedNCT02664207Not applicable1 country
- Risk Factors Associated With Spontaneous Preterm Delivery Status Post Open Fetal Myelomeningocele RepairCompletedNCT03073382
- Stress-associated Epigenetic Alterations in Newborns After Fetal SurgeryCompletedNCT040273741 country
- Retrograde Colonic Irrigation to Manage Spina Bifida Functional Digestive Sequelae: a Multicenter, Prospective, Randomized Controlled TrialCompletedNCT02361450Not applicable1 country
- Prospective Cohort of Transitional Urology PatientsStatus unknownNCT030610841 country
- the Effects of Platelet-Rich Plasma on Postoperative Complications After MeningomyeloceleCompletedNCT05711355Not applicable1 country
- A Two-week Open-label Pharmacodynamic and Pharmacokinetic Study of Multiple Doses of a Darifenacin Liquid Oral Suspension in Children (2 - 15 Years) With Neurogenic Detrusor OveractivityTerminatedNCT00712322Phase 22 countries
- In Utero Repair of Myelomeningocele: Atosiban Versus TerbutalineCompletedNCT044685681 country
- Propellers Flaps for Meningomylocele DefectsCompletedNCT05188300Not applicable1 country
- Telemedicine in Spina Bifida Transition: A Pilot StudyCompletedNCT03466996Not applicable1 country
- Efficacy of Contrast Enhanced Voiding Urosonography for Urodynamic StudiesStatus unknownNCT047385391 country
- Effects of Physical Therapy Associated With Photobiomodulation on MyelomeningoceleStatus unknownNCT04425330Not applicable
- Management of Myelomeningocele Study (MOMS)CompletedNCT00060606Not applicable1 country
- Fetoscopic Open Spina Bifida Repair Using the SAFER TechniqueCompletedNCT043567031 country
- Daily Physical Activity in MyelomeningoceleCompletedNCT04186338
- Evaluation of Hysterotomy Site After Open Fetal SurgeryTerminatedNCT02493062Not applicable1 country
- Fetal Myelomeningocele Repair With Maternal BMI Between 35.0 and 40.0TerminatedNCT02509377Not applicable1 country
- Open Spina Bifida Fetoscopic Repair ProjectStatus unknownNCT03562286Not applicable1 country
- Can Dynamic Ultrasonography Replace Urodynamics in Follow-up of Patients With MyelomeningoceleCompletedNCT03550898Not applicable