An observational study in Tethered Cord Syndrome, sponsored by Assiut University. Status unknown. Open to participants aged 1 Year to 16 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-11-03.
Sponsored by Assiut University · Observational
The aim of this study is to assess surgical management and outcome of Tethered cord syndrome
Tethered cord syndrome (TCS) is a developmental abnormality of the neuroaxis which is usually diagnosed in childhood. The actual tethering has been attributed to a variety of pathologic entities, including a thickened tight filum terminale , intradural lipomas with or without a connecting extradural component, intradural fibrous adhesions, diastematomyelia, and adherence of the neural placode following previous closure of a myelomeningocele. However, sufficient differences in the mode of onset, clinical manifestations, and outcome exist between pediatric and adolescent patients with tethered cord to warrant a more detailed analysis of the adult syndrome. The most problematic technical consideration in surgery for the release of the tethered cord is how to preserve functioning neural elements and rebuild the dural sac to avoid CSF leak. The purpose of this study is to review causes of Tethered cord, clinical presentation, diagnostic tools, treatment options and outcome in school-aged children, adolescents, and young adults with Tethered cord.
49 studies on the registry are indexed under Neural Tube Defects; 11 are open to participants now.
This study's planned enrollment of 35 is below the median of 123 across 22 observational studies indexed under Neural Tube Defects.
Browse Neural Tube Defects studies →Assiut University is the lead sponsor of 4,901 studies on the registry; 2,098 are open to participants now.
Of its 13 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
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Males and Females below 16 years old with Tethered cord syndome
Exclusion Criteria:
Release of the tethered spinal cord
Motor power
Outcome of Detethering of the Tethered spinal cord according to Motor power of the lower limbs 5 grades 0: No visible muscle contraction 1. Visible muscle contraction with no or trace movement 2. Limb movement, but not against gravity 3. Movement against gravity but not resistance 4. Movement against at least some resistance supplied by the examiner 5. Full strength
Time frame: Two years
Sensations
Outcome of Detethering of the Tethered spinal cord according to the sensations of lower limbs , is there decreased sensations of lower limbs and if improved or not
Time frame: Two years
Sphincter's function
Outcome of Detethering of the Tethered spinal cord according to is there urinary incontinence or stool incontinence and if improved or not
Time frame: Two years
No study locations are listed for this record.
Plan to share: Yes — The aim of this study is to assess surgical management and outcome of Tethered cord syndrome.
Supporting information: Csr
No publications or documents are linked to this record.
This study is status unknown, as verified in Nov 2022. You cannot join it, but the record below documents what was studied.
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Assiut University