Necrosis clinical trials
The registry lists 90 studies for Necrosis across more than 10 countries. 23 are recruiting or about to start. 40 of them are mainly about Necrosis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09. Counting its 18 narrower conditions too, such as Myocardial Infarction: 4,356 studies, 915 open.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
Cairo University (5) · Erasmus Medical Center (2) · Smith & Nephew Orthopaedics AG (2) · University of Wisconsin, Madison (2) · Plexaa Ltd (2) · Stryker Trauma and Extremities (2) · Seoul National University Hospital (2) · BioMed Valley Discoveries, Inc (2)
What is being tested here
Drugs under test in Necrosis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 6, phase 3 first
- Nov 2027ORal Antibiotics in Acute Mesenteric Ischemia · Phase 3 · Assistance Publique - Hôpitaux de Paris
- Dec 2026Prediction of ICG for Skin Necrosis in Mastectomy With Immediate Reconstruction · University Medical Center Groningen
- Dec 2026Randomized Evaluation of Indocyanine Green Fluorescence Angiography-Guided Versus Standard Clinical Perfusion Assessment During Gluteal Permanent Synthetic Filler Removal · Research Inc
- Dec 2026Cold Dissection Versus Electrocautery Dissection in Endoscopic Nipple-Sparing Mastectomy and Immediate Implant-Based Reconstruction: A Randomized Controlled Trial · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
- Mar 2027Fluorescence-based Detection of Inflammation and Necrosis to Inform Surgical Decision-making and Enhance Outcomes · University of Wisconsin, Madison
- May 2027Talus Replacement Registry · Kyle Schweser MD
Who these studies take
Of the 14 Necrosis studies recruiting now, 8 (57%) set no upper age limit and 1 (7%) stop at 75 or younger. 0 (0%) take children under 18. 3 (21%) are for women only and 0 (0%) for men only; 1 (7%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 14 (100%) | 11 (79%) |
| 30 | 14 (100%) | 11 (79%) |
| 40 | 14 (100%) | 11 (79%) |
| 50 | 14 (100%) | 11 (79%) |
| 65 | 14 (100%) | 11 (79%) |
| 75 | 14 (100%) | 11 (79%) |
| 85 | 12 (86%) | 10 (71%) |
Across all 90 studies, recruiting or not: 34% stop at 75 or younger and 24% at 65; 18% take children; 16% are for women only and 1% for men only; 16% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 50 of 90. Browse all 90 → or search them.
- Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal HistologiesRecruitingNCT04847063Phase 11 country
- Autologous Bone Marrow Aspirate Treatment for Early-Stage OsteonecrosisRecruitingNCT06123481Not applicable1 country
- Randomized Evaluation of Indocyanine Green Fluorescence Angiography-Guided Versus Standard Clinical Perfusion Assessment During Gluteal Permanent Synthetic Filler RemovalNot yet recruitingNCT07808957Not applicable1 country
- Prophylactic Anti-Seizure Medication vs No Anti-Seizure Medication for Patients With Primary Motor Cortex Brain MetastasesRecruitingNCT07130786Phase 21 country
- The Effect of Proton Pump Inhibitors(PPIs) on Endoscopic Treatment of Walled-off Necrosis (WON)RecruitingNCT07488299Not applicable1 country
- DRONE-WOUND Study: Severe Infection After Drone-Related Combat TraumaNot yet recruitingNCT077066081 country
- Necrosectomy With Cryotechnology for Accelerated RemovalRecruitingNCT06553651Not applicable1 country
- Talus Replacement RegistryRecruitingNCT039651431 country
- Pseudomembrane Removal for Post-RT Nasopharyngeal NecrosisNot yet recruitingNCT07552883Not applicable
- B4P Trial - BLOOM43 for PreconditioningNot yet recruitingNCT07340632Not applicable
- To Evaluate Early (2-Week) vs. Standard (4-Week) Metal Stent Removal Following Endoscopic Ultrasound Guided WON DrainageRecruitingNCT07307248Not applicable1 country
- Plexaa For Preconditioning: Gender Affirming MastectomyRecruitingNCT06502353Not applicable1 country
- PMCF Study on the Safety, Performance and Clinical Benefits Data of the Anatomical Shoulder 2.0 Fracture SystemRecruitingNCT053511121 country
- Conventional Endoscopic Techniques Versus EndoRotor® System for Necrosectomy of Walled of NecrosisEnrolling by invitationNCT04814693Not applicable6 countries
- Prediction of ICG for Skin Necrosis in Mastectomy With Immediate ReconstructionNot yet recruitingNCT06956443
- The Effects of Post-Operative Interventions on Surgical Site Occurrences in AWRRecruitingNCT04906408Not applicable1 country
- The Application of Kinesio Taping Technique in the Early Upper Limb Functional Activities Induction of Hemiplegic Patients After StrokeNot yet recruitingNCT06834750Not applicable1 country
- ORal Antibiotics in Acute Mesenteric IschemiaRecruitingNCT06387147Phase 31 country
- Cold Dissection Versus Electrocautery Dissection in Endoscopic Nipple-Sparing Mastectomy and Immediate Implant-Based Reconstruction: A Randomized Controlled TrialRecruitingNCT06024187Not applicable1 country
- This Study Aims to Explore the Efficacy of Hyperbaric Oxygen in the Treatment of Flap Ischaemic Necrosis After Breast Cancer SurgeryNot yet recruitingNCT06811857Not applicable1 country
- Efficacy of Angiography With Indocyanine Green in the Identification of Complications After Breast SurgeryRecruitingNCT059109311 country
- Monitoring of the Bone Free Flaps With MicrodialysisRecruitingNCT03935139Not applicable1 country
- Sterile Wound Care Liquid Dressing in Treatment of Diabetic Ulcer in Necrosis Stable Stage: a Randomized Control TrialNot yet recruitingNCT05975827Not applicable
- Early Intracoronary N-Acetylcysteine During Primary PCI in STEMI: A Pilot Randomized Trial of Reperfusion Injury Biomarkers and Functional RecoveryCompletedNCT06850831Phase 21 country
- Fluorescence-based Detection of Inflammation and Necrosis to Inform Surgical Decision-making and Enhance OutcomesActive, not recruitingNCT055935231 country
- A Post Market Clinical Follow-up Study With the aneXys CupActive, not recruitingNCT032748301 country
- Safety Profile of Ropivacaine in Dorsal Penile Nerve Block for Male Circumcision: a Large Cohort Study in ChildrenCompletedNCT06545058
- a Prospective Study of Surgical Results, Complications and Predictive Values in Chinese Women Breast ReconstructionCompletedNCT067790191 country
- NANOS Neck Preserving Hip StemTerminatedNCT040362793 countries
- Effects of Vasopressor on the Graft Blood Flow in TRAMCompletedNCT05049278Not applicable1 country
- Adverse Radiation Effects After Gamma Knife Radio Surgery and Hyperbaric Oxygen TherapyCompletedNCT02714465Not applicable1 country
- A Comparison Between Lumen-apposing Metal Stent and Double-pigtail Plastic Stents for Treatment of Walled-off NecrosisCompletedNCT04876235Not applicable1 country
- Clinical and Radiographic Evaluation of the Synergistic Effect of Nano Silver Particles and Calcium Hydroxide Versus Triple Antibiotic Paste as Antibacterial Agents for Lesion Sterilization and Tissue Repair (LSTR) in Necrotic Primary MolarsStatus unknownNCT05681221Not applicable
- Effect of Diclofenac Sodium Versus Calcium Hydroxide as Intracanal Medication on the Intensity of Postoperative Pain, Bacterial Load Reduction and MMP-9 Levels in Patients With Necrotic Pulp.Status unknownNCT05582421Early Phase 1
- Nitropaste in Breast ReductionWithdrawnNCT04321967Phase 31 country
- Inflammatory Biomarkers in Psychogenic Non-epileptic SeizureStatus unknownNCT05571371
- 10-Years Follow-up of the EXAMINATION TrialCompletedNCT044623153 countries
- The Contributions of the Multidisciplinary Management of Prosthesis Knee Infections in a Reference Center: A Retrospective Study About 52 Cases.Skin Coverage in a Reference Center: A Retrospective Study About 52 CasesStatus unknownNCT053677261 country
- A Randomized Controlled Clinical Trial of Surgery Versus Conservative Treatment for Mild and Moderate-grade Nasopharyngeal NecrosisStatus unknownNCT05228093Not applicable1 country
- NECROtizing Soft Tissue Infections and Their Scoring SystemStatus unknownNCT052248171 country
- Wound Necrosis in Lower Extremity SurgeryCompletedNCT033513871 country
- Integrated Clinical-radiological Analysis of Hypoxia Markers in Pediatric OsteosarcomasStatus unknownNCT051078431 country
- Phase I Study for Autologous Dermal Substitutes and Dermo-epidermal Skin Substitutes for Treatment of Skin DefectsCompletedNCT02145130Phase 11 country
- Near Infrared Imaging and Flap NecrosisCompletedNCT03476499Not applicable1 country
- Covered Stents Versus Bare-Metal StentsStatus unknownNCT02428582Not applicable1 country
- Feasibility of the IC-Flow Device for Fluorescent Perfusion Evaluation During Feasibility of the IC-Flow DeviceCompletedNCT038604931 country
- The Use of Indocyanine Green Angiography to Predict Expanded Flap ViabilityStatus unknownNCT040976651 country
- Humeral Head Implants: Radiological and Clinical EvaluationActive, not recruitingNCT02754024
- Treatment of Osteonecrosis of the Femoral Head by Bone Marrow TransplantationCompletedNCT00821470Phase 11 country
- Novel Application of Indocyanine Green as a Biomarker to Identify Tissue Necrosis in Mastectomy PatientsCompletedNCT04145323Early Phase 11 country