Our grouping. This page groups the registry's lead sponsor names by company — our grouping, not the registry's. It can be wrong or incomplete: an acquired company whose name never mentions its owner may be missing. Use “Something wrong?” under any name below to correct it.
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Smith & Nephew, Inc. clinical trials
The registry lists 214 studies whose lead sponsor is Smith & Nephew, Inc. or one of 9 companies grouped under it. 12 are recruiting or about to start. Per ClinicalTrials.gov, last updated Oct 8, 2026.
Keep track of what changes. Save the Smith & Nephew, Inc. studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
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Registry sponsor names on this page
Each name exactly as ClinicalTrials.gov lists it, and how it relates to Smith & Nephew, Inc..
- Smith & Nephew, Inc.133 studiesSame company
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- 34 studies →
- Smith & Nephew Orthopaedics AG24 studies →Acquired — became part of Smith & Nephew, Inc., May 31, 2007 · source ↗
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- Osiris Therapeutics7 studies →Acquired — became part of Smith & Nephew, Inc., Apr 17, 2019 · source ↗
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- ENTrigue Surgical, Inc.4 studies →Acquired — became part of Smith & Nephew, Inc., May 29, 2014 · source ↗
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- Smith & Nephew Medical (Shanghai) Ltd4 studies →Regional office
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- Tusker Medical3 studies →Acquired — became part of Smith & Nephew, Inc., Jan 23, 2020 · source ↗
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- Smith & Nephew Orthopaedics (Beijing) Limited2 studies →Acquired — became part of Smith & Nephew, Inc., May 31, 2007 · source ↗
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- Leaf Healthcare, Inc.1 study →Acquired — became part of Smith & Nephew, Inc., Apr 17, 2019 · source ↗
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- Integrity Orthopaedics, Inc.1 study →Acquired — became part of Smith & Nephew, Inc., Jan 21, 2026 · source ↗
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- Smith & Nephew Pte Ltd1 studySame company
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Focus areas
Conditions Smith & Nephew, Inc. leads ten or more studies in, by study count. A broader condition is left out when almost all its studies are already in a narrower one listed here.
Studies
Recruiting first, then most recently updated. Showing 50 of 214. Browse all 214 →
- Knee Cartilage Repair RegistryRecruitingNCT07786207
- Sacrum Pressure Injury Prevention Study Using ALLEVYN◊ Complete Care in Adults at Risk of Developing Hospital-acquired Pressure Injuries in Critical Care UnitsNot yet recruitingNCT07849387Not applicable
- Use of the REGENETEN™ Bioinductive Implant System in High Grade Partial-thickness TearsRecruitingNCT05444465Not applicable
- A Multi-Center Study Assessing the Safety and Efficacy of the LEGION Medial Stabilized (MS) Insert in Patients Undergoing a Total Knee Arthroplasty (TKA)RecruitingNCT07199738
- A Post Approval Multicenter 10 Year Follow-up Observational Trial of Marketed Product - MP01 vs. Surgical Standard of Care (SSOC) Used for the Treatment of Joint Surface Lesions of the KneeEnrolling by invitationNCT06916728
- Evaluation Of Outcomes Following Rotator Cuff Repair Using the REGENETEN Bioinductive ImplantRecruitingNCT06857084
- Study to Evaluate the Safety and Effectiveness of the REAL INTELLIGENCE™ CORI™ in Total Knee Arthroplasty (TKA) ProcedureRecruitingNCT04848896Not applicable
- Post-Market Clinical Study to Evaluate the Safety and Effectiveness of REFLEX ULTRA 45 for Coblation Inferior Turbinate Reduction in ChinaRecruitingNCT07025304Not applicable
- Clinical Trial on the Effect of the Flexible Suturing System With Anchors (FSSA) in Full-thickness Rotator Cuff Tendon TearsEnrolling by invitationNCT06868108
Sponsor listed in the registry: Integrity Orthopaedics, Inc. · First submitted before Integrity Orthopaedics, Inc. became part of Smith & Nephew, Inc.
- A Multicenter, Post-Market Clinical Follow-up Study of Subjects With the REDAPT™ System Monolithic Sleeveless/Sleeved Stem and/or Fully Porous Acetabular Shell With XLPE Liner and/or Modular Shell Components Previously ImplantedEnrolling by invitationNCT03610789
- Evaluation of Outcomes Following In-office Tympanostomy Using the Tula® System: a Prospective, Multi-center RegistryRecruitingNCT05915078
- AETOS Shoulder SystemRecruitingNCT06319911
- Journey II BCS EU Observational TrialActive, not recruitingNCT02211794
Sponsor listed in the registry: Smith & Nephew Orthopaedics AG · First submitted after Smith & Nephew Orthopaedics AG became part of Smith & Nephew, Inc.
- Safety and Effectiveness Study of OR3O™ Dual Mobility System in THAActive, not recruitingNCT04325022
- A Global Clinical Study Investigating the Safety and Effectiveness of Smith and Nephew's Porous Knee System in Patients Who Need a Total Knee Replacement Due to Degenerative Arthritis, Post-traumatic Arthritis or Inflammatory ArthritisActive, not recruitingNCT05197036
- Safety and Performance of MICRORAPTOR™ Suture Anchors in Shoulder and HipCompletedNCT03985839
- To Evaluate the Performance of the CORI™ KNEE TENSIONER as an Accessory to the CORI™ Surgical System.CompletedNCT04849884Not applicable
- Long Term Follow-up of Integra® Cadence™ Total Ankle System in Primary Ankle Joint ReplacementTerminatedNCT03247023
- JOURNEY™ II CR Total Knee SystemActive, not recruitingNCT02440672
- Human Participant Study of a Prototype Multilayer Foam Dressing on Intact Skin.CompletedNCT06831448Not applicable
- Safety and Performance Study of the Legion Porous System in Total Knee ArthroplastyActive, not recruitingNCT03720782
- Safety of Treatment of Shoulder RepairCompletedNCT04552119
- A Safety and Efficacy Study of the Birmingham Hip Resurfacing SystemCompletedNCT00611585
- Human Participant Study of Prototype Non-medicated Multilayer Foam Dressings on Intact SkinCompletedNCT06700850Not applicable
- OXINIUM◊ DH Total Hip Arthroplasty Pivotal StudyActive, not recruitingNCT02353377
- Safety and Performance Study of the FAST-FIX FLEX System for Meniscal Repairs and Meniscal TransplantationsCompletedNCT04903106
- TITAN™ Reverse Shoulder SystemTerminatedNCT02204228
- A Multi-Centre Study in Patients Undergoing Total Hip Arthroplasty With the Smith+Nephew CATALYSTEM™ Primary Hip SystemActive, not recruitingNCT06564636
- Ten Year Implant Survivorship of the ANTHEM™ PS Total Knee SystemActive, not recruitingNCT03078543
- Safety and Efficacy of the ANTHEM™ CR Total Knee SystemActive, not recruitingNCT03885622
Sponsor listed in the registry: Smith & Nephew Pte Ltd
- Safety and Performance of the Journey™ II UNI Unicompartmental Knee SystemCompletedNCT03768128
- Circumferential Compression STITCH Repairs of Complex and Horizontal Cleavage Meniscal TearsTerminatedNCT04361487
- Safety and Performance Using Legion™ CR Oxinium and CoCr Femoral Implants Combined With Legion™/Genesis™ II XLPE High Flex Tibial InsertsActive, not recruitingNCT03687593
- POLARSTEM Cementless Hip StemCompletedNCT02648152
- PICO Venous Leg Ulcers (VLU) Reimbursement StudyTerminatedNCT06510777Not applicable
- Prospective Single-center Long-term Observation of the SL-PLUS® MIA StemCompletedNCT04122157
Sponsor listed in the registry: Smith & Nephew Orthopaedics AG · First submitted after Smith & Nephew Orthopaedics AG became part of Smith & Nephew, Inc.
- A Multi-center Outcomes Clinical Study of the PyroTITAN™ HRA Shoulder Implant in Humeral Head ResurfacingCompletedNCT02405208
- Post Market Clinical Follow Up of LEGION™ Primary TKS With VERILAST™Active, not recruitingNCT02380092
- Agili-C™ Implant Performance EvaluationCompletedNCT03299959Not applicable
- Study to Evaluate Patient Outcomes and Safety and Effectiveness of Robotic Assisted Unicompartmental Knee Replacements Versus Conventional Unicompartmental Knee for Subjects With Primary Arthritis of the Knee Joint Involving One (UKA) Compartment (Medial or Lateral)WithdrawnNCT06036212Not applicable
- A Clinical Study on New Negative Pressure Wound Therapy Dressing in the Management of Chronic & Acute WoundsTerminatedNCT06306716
- Study to Evaluate the Safety and Effectiveness of REAL INTELLIGENCE™ CORI™ in Knee Arthroplasty ProceduresCompletedNCT04786119Not applicable
- Evaluate the Performance of JOURNEY II CR in TKA PopulationsTerminatedNCT04818840
- Study to Evaluate the PICO 14 Negative Pressure Wound Therapy System in the Management of Acute and Chronic WoundsTerminatedNCT05234632
- REGENETEN™ Bioinductive Implant System in Full-thickness TearsTerminatedNCT04450342Not applicable
- Study to Evaluate the Safety and Efficacy of OR3O™ Dual Mobility System vs. Conventional Single Bearing Design Total Hip SystemTerminatedNCT04941729Not applicable
Sponsor listed in the registry: Smith & Nephew Medical (Shanghai) Ltd
- R3 Delta Ceramic Acetabular System PAS U.S.CompletedNCT03056534
- EU Safety and Efficacy Study Regarding the R3 Acetabular Hip SystemCompletedNCT04399928
Sponsor listed in the registry: Smith & Nephew Orthopaedics AG · First submitted after Smith & Nephew Orthopaedics AG became part of Smith & Nephew, Inc.
- Safety and Effectiveness of BIOSURE RG in Cruciate Ligaments Reconstruction in ChineseCompletedNCT04012567Not applicable
- Study to Evaluate the Safety and Effectiveness of REAL INTELLIGENCE™ CORI™ in Unicondylar Knee Arthroplasty (UKA) ProceduresTerminatedNCT04797897Not applicable