Stroke, Lacunar clinical trials
The registry lists 21 studies for Stroke, Lacunar across more than 10 countries. 9 are recruiting or about to start. 13 of them are mainly about Stroke, Lacunar (how this is decided). Per ClinicalTrials.gov, last updated 2026-09-08.
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Who runs them
Yonsei University (2) · University of Cambridge (2) · University of British Columbia (2) · Synchron Medical, Inc. (2) · University of Edinburgh (2) · University of L'Aquila (1) · Herlev Hospital (1) · Nippon Medical School (1)
What is being tested here
Drugs under test in Stroke, Lacunar studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 3, phase 3 first
- Aug 2027Isosorbide Mononitrate and Butylphthalide to Reduce the Risk of Disability in Patients With Acute Lacunar Stroke (IMPACT) · Phase 3 · Beijing Tiantan Hospital
- Sep 2027CompARing Between CO2 Phenylephrine and Phenylephrine Only Treatment in Patients With proGrEssing Cerebral infarctioN · Phase 3 · Yonsei University
- Dec 2026Telecoached Exercise Intervention for Connectivity Enhancement in Small Vessel Disease (TELECONNECT-SVD) · University of L'Aquila
Who these studies take
Of the 7 Stroke, Lacunar studies recruiting now, 6 (86%) set no upper age limit and 0 (0%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 4 (57%) | 4 (57%) |
| 30 | 4 (57%) | 4 (57%) |
| 40 | 6 (86%) | 6 (86%) |
| 50 | 6 (86%) | 6 (86%) |
| 65 | 7 (100%) | 7 (100%) |
| 75 | 7 (100%) | 7 (100%) |
| 85 | 7 (100%) | 7 (100%) |
Across all 21 studies, recruiting or not: 10% stop at 75 or younger and 0% at 65; 0% take children; 0% are for women only and 0% for men only; 5% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 21 of 21. search them.
- Lacunar Stroke hyperAcute Clinical Utilization of Novel Approach Regimens: Rt-PA vs. DAPT Randomised Clinical TrialRecruitingNCT07111559Phase 41 country
- Retinal Vessel Leakage in Cerebral Small Vessel DiseaseRecruitingNCT064163711 country
- A Multicenter Randomized Clinical Trial Compared With Standard Clinical Practice to Evaluate the Efficacy of a Polyphenol-rich Salicornia Extract in the Progression of Cognitive Decline in a Cohort of Patients With Lacunar Infarcts (SALACUNAR)RecruitingNCT07353424Not applicable1 country
- Telecoached Exercise Intervention for Connectivity Enhancement in Small Vessel Disease (TELECONNECT-SVD)RecruitingNCT06525987Not applicable1 country
- Isosorbide Mononitrate and Butylphthalide to Reduce the Risk of Disability in Patients With Acute Lacunar Stroke (IMPACT)Not yet recruitingNCT07252544Phase 3
- The Relationship Between Controlling Risk Factors and Cerebral Haemodynamics in Lacunar StrokeRecruitingNCT063548811 country
- CompARing Between CO2 Phenylephrine and Phenylephrine Only Treatment in Patients With proGrEssing Cerebral infarctioNNot yet recruitingNCT06770426Phase 31 country
- INflammation and Small Vessel Disease StudyRecruitingNCT057462212 countries
- Constitution of a Clinico-radiological Database and a Biobank for Patients With Lacunar InfarctsRecruitingNCT035529261 country
- COMMAND Early Feasibility Study: Implantable BCI to Control a Digital Device for People With ParalysisActive, not recruitingNCT05035823Not applicable1 country
- Comparing Between CO2 and Phenylephrine Treatment in Patients With Progressive Lacunar Infarction (CARBOGEN Study)TerminatedNCT04839224Phase 31 country
- LACunar Intervention (LACI-2) Trial-2CompletedNCT03451591Phase 2/31 country
- Detection of Silent Atrial Fibrillation aFter Ischemic StrOkeCompletedNCT02684825Not applicable1 country
- Comparison Between Unihemispheric and Bihemispheric TCDS in Subacute Ischemic Stroke PatientsCompletedNCT04770363Not applicable1 country
- SWITCH II Early Feasibility Study: Implantable BCI to Control a Digital Device for People With ParalysisWithdrawnNCT05041114Not applicable1 country
- Virtual Reality, Mood, and Sedentary Behaviour After StrokeTerminatedNCT04011202Not applicable1 country
- Effect of Remote Ischemic Conditioning on Vascular Health in Stroke PatientsCompletedNCT03635177Not applicable1 country
- Cambridge 7 Tesla Cerebral Small Vessel Disease StudyStatus unknownNCT043302221 country
- The Effect of Aerobic Exercise in Patients With Lacunar StrokeStatus unknownNCT02731235Not applicable1 country
- Effect of Tadalafil on Cerebral Large Arteries in StrokeCompletedNCT02801032Phase 21 country
- Secondary Prevention of Small Subcortical Strokes TrialCompletedNCT00059306Phase 37 countries