An interventional study of More myopic eye: MCL1; Less myopic eye: MCL2 in Anisometropia and Myopia, sponsored by Essilor International. Recruiting at 1 site in Singapore. Open to participants aged 6 Years to 13 Years. Per ClinicalTrials.gov, last updated 2026-09-15.
Sponsored by Essilor International · Not applicable, Interventional, and Treatment
The goal of this clinical trial is to learn if our research spectacles will lower the difference in prescription (spectacles degree) between the eyes in children between 6 to 13 years old with anisometropic myopia. Anisometropic myopia is when the difference in myopia prescription between the two eyes are more than 1 diopter. The main question it aims to answer is:
How the eye responds to the research spectacles over time by measuring:
Change in cycloplegic spherical equivalent refraction: an accurate measurement of the eye's prescription taken while the focusing muscles are temporarily relaxed with eye drops.
Participants will:
Exclusion Criteria:
Each participant wears the study eyeglasses containing both Myopia Control Lens 1 (MCL1) and Myopia Control Lens 2 (MCL2) design, with one type of lens in each eye throughout the study period. MCL1 will be worn in the more myopic eye, and MCL2 in the less myopic eye for a period of 12 months.
Device: More myopic eye: MCL1; Less myopic eye: MCL2
Each participant wears the study eyeglasses containing both Myopia Control Lens 1 (MCL1) and Myopia Control Lens 2 (MCL2) design, with one type of lens in each eye throughout the study period. MCL1 will be worn in the more myopic eye, and MCL2 in the less myopic eye for a period of 12 months.
Change in axial length difference between the eyes
Time frame: Base line, 12 months
Change in cycloplegic spherical equivalent refraction between the eyes
Time frame: Baseline, 12 months
Change in axial length difference between the eyes
Time frame: Baseline, 6 months
Effect of baseline higher order aberrations on the change in axial length
Time frame: Baseline, 6 months, 12 months
Effect of wearing compliance on the change in axial length
Time frame: Baseline, 6 months, 12 months
Plan to share: No
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Essilor International