An interventional study of More myopic eye: MCL1; Less myopic eye: MCL2 in Anisometropia and Myopia, sponsored by Essilor International. Recruiting at 1 site in Singapore. Open to participants aged 6 Years to 13 Years. Per ClinicalTrials.gov, last updated 2026-09-15.
Sponsored by Essilor International · Not applicable, Interventional, and Treatment
The goal of this clinical trial is to learn if our research spectacles will lower the difference in prescription (spectacles degree) between the eyes in children between 6 to 13 years old with anisometropic myopia. Anisometropic myopia is when the difference in myopia prescription between the two eyes are more than 1 diopter. The main question it aims to answer is:
How the eye responds to the research spectacles over time by measuring:
Change in cycloplegic spherical equivalent refraction: an accurate measurement of the eye's prescription taken while the focusing muscles are temporarily relaxed with eye drops.
Participants will:
31 studies on the registry are indexed under Anisometropia; 10 are open to participants now.
This study's planned enrollment of 20 is below the median of 58 across 24 interventional studies indexed under Anisometropia.
Browse Anisometropia studies →Essilor International is the lead sponsor of 38 studies on the registry; 20 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Contraindication
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Each participant wears the study eyeglasses containing both Myopia Control Lens 1 (MCL1) and Myopia Control Lens 2 (MCL2) design, with one type of lens in each eye throughout the study period. MCL1 will be worn in the more myopic eye, and MCL2 in the less myopic eye for a period of 12 months.
Device: More myopic eye: MCL1; Less myopic eye: MCL2
Each participant wears the study eyeglasses containing both Myopia Control Lens 1 (MCL1) and Myopia Control Lens 2 (MCL2) design, with one type of lens in each eye throughout the study period. MCL1 will be worn in the more myopic eye, and MCL2 in the less myopic eye for a period of 12 months.
Change in axial length difference between the eyes
Time frame: Base line, 12 months
Change in cycloplegic spherical equivalent refraction between the eyes
Time frame: Baseline, 12 months
Change in axial length difference between the eyes
Time frame: Baseline, 6 months
Effect of baseline higher order aberrations on the change in axial length
Time frame: Baseline, 6 months, 12 months
Effect of wearing compliance on the change in axial length
Time frame: Baseline, 6 months, 12 months
Plan to share: No
Started Aug 2026 (actual). Primary completion is estimated for Nov 2027, 15 months after the start.
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