Myopia, Degenerative clinical trials
The registry lists 71 studies for Myopia, Degenerative across more than 10 countries. 20 are recruiting or about to start. 50 of them are mainly about Myopia, Degenerative (how this is decided). Per ClinicalTrials.gov, last updated 2026-09-14.
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Who runs them
Shanghai Eye Disease Prevention and Treatment Center (7) · Zhongshan Ophthalmic Center, Sun Yat-sen University (4) · Beijing Airdoc Technology Co., Ltd. (4) · Tianjin Eye Hospital (4) · Menicon Co., Ltd. (3) · Novartis Pharmaceuticals (2) · Cloudbreak Therapeutics, LLC (1) · National Taiwan University Hospital (1)
What is being tested here
Drugs under test in Myopia, Degenerative studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Ranibizumab | 0 | 2 | 5 |
| Atropine | 0 | 0 | 2 |
| Trabedersen | 0 | 1 | 1 |
| Carboxymethylcellulose | 0 | 0 | 1 |
| Glycerol | 0 | 0 | 1 |
| Aflibercept | 0 | 1 | 1 |
| Fosbretabulin | 0 | 0 | 1 |
| Bevacizumab | 0 | 0 | 1 |
| Ophthalmic Solutions | 0 | 0 | 1 |
Drug classes tested here Angiogenesis inhibitors 7
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 9, phase 3 first
- Mar 2027Study of OT-101 in Treating Myopia · Phase 3 · Ocumension (Hong Kong) Limited
- Oct 2027Study to Evaluate the Efficacy of Alleance® (Atropine Sulfate 0.01%) as a Treatment to Delay Myopia and Axial Ocular Elongation in Children. · Phase 3 · Laboratorios Sophia S.A de C.V.
- Dec 2026A Study of SHJ002 Sterile Ophthalmic Solution for Myopia Control · Sunhawk Vision Biotech, Inc.
- Dec 2026Safety and Efficacy of Blue Star MAX-5 Lenses in Myopia Control · Zhongshan Ophthalmic Center, Sun Yat-sen University
- Apr 2027Multicenter RCT: LED Red Light Dose-Response in Myopia Progression Control · Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
- Jul 2027Novel Lenses for Myopia Progression Trial · Shanghai Eye Disease Prevention and Treatment Center
- Aug 2027Myopia Control Combined PBM With Myopic Defocus Lens in Children · Beijing Airdoc Technology Co., Ltd.
- Sep 2027Management of Myopia in University Students Using Dual Focus Soft Contact Lenses · University of Bradford
- Sep 2027Myopia Progression With Freeform Myopia Control Spectacles · Shanghai Eye Disease Prevention and Treatment Center
Who these studies take
Of the 9 Myopia, Degenerative studies recruiting now, 1 (11%) set no upper age limit and 7 (78%) stop at 75 or younger. 7 (78%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 3 (33%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 6 (67%) | 6 (67%) |
| 18 | 0 (0%) | 0 (0%) |
| 30 | 1 (11%) | 1 (11%) |
| 40 | 2 (22%) | 2 (22%) |
| 50 | 2 (22%) | 2 (22%) |
| 65 | 2 (22%) | 2 (22%) |
| 75 | 2 (22%) | 2 (22%) |
| 85 | 2 (22%) | 2 (22%) |
Across all 71 studies, recruiting or not: 75% stop at 75 or younger and 75% at 65; 70% take children; 0% are for women only and 0% for men only; 42% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Myopia, Degenerative studies take
Of 30 interventional studies with no phase under Myopia, Degenerative, half reached primary completion within 40 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 40 mo30–96 · 30 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 71. Browse all 71 → or search them.
- Predictors of Vitrectomy Outcomes in Myopic FoveoschisisRecruitingNCT07774637Not applicable1 country
- Management of Myopia in University Students Using Dual Focus Soft Contact LensesEnrolling by invitationNCT05955638Not applicable1 country
- Retinal Clinical Assessment With AI-derived Quantitative InformationNot yet recruitingNCT07291960
- Efficacy of Different Interventions for Progressive Myopia After Orthokeratology Lens WearNot yet recruitingNCT07494799
- Multicenter RCT: LED Red Light Dose-Response in Myopia Progression ControlNot yet recruitingNCT07330180Not applicable1 country
- An Interpretable Fundus Diseases Report Generating System Based On Weakly LabelingsNot yet recruitingNCT069180281 country
- Study to Evaluate the Efficacy of Alleance® (Atropine Sulfate 0.01%) as a Treatment to Delay Myopia and Axial Ocular Elongation in Children.RecruitingNCT06389110Phase 31 country
- A Prospective, Randomized Clinical Study of Two Phakic Toric Implantable LensesRecruitingNCT06839898Not applicable2 countries
- Multicenter Evaluation of Near Vision and Outdoor Time in Kids StudyRecruitingNCT061192432 countries
- Differences and Wearing Safety and Comfort of New Defocus Incorporated Multiple Segments Spectacle LensesEnrolling by invitationNCT06221592Not applicable1 country
- To Evaluate the Efficacy and Safety of an Defocus Lens in Slowing the Progression of MyopiaNot yet recruitingNCT06405711Not applicable1 country
- Effect of Atropine on Pupil Size and Quality of VisionNot yet recruitingNCT06071260Not applicable1 country
- Myopia Preventing With Distance-image ScreenRecruitingNCT06088225Not applicable1 country
- Efficacy of IVMED-85 on Pediatric MyopiaNot yet recruitingNCT05761795Phase 1/2
- Clinical Study of Light Therapy to Control Myopia Progression in ChildrenRecruitingNCT05761379Not applicable1 country
- Low Concentration Atropine in the Prevention of Myopia in Children.RecruitingNCT05939882Not applicable1 country
- Slow Myopia Progression With Different Irradiance LightRecruitingNCT05881655Not applicable1 country
- Myopia Control Combined PBM With Myopic Defocus Lens in ChildrenRecruitingNCT05756959Not applicable1 country
- Efficacy and Safety of Low-concentration Atropine for Myopia Control in Chinese Children and AdolescentsNot yet recruitingNCT05597163Not applicable
- Choroidal Change on OCTA in Eyes With High MyopiaNot yet recruitingNCT04255524Not applicable1 country
- MAD Trial: Myopia Atropine DoseActive, not recruitingNCT05667454Phase 31 country
- Evaluation of the Safety and Efficacy of the D.D.C Dual-control Technology Spectacle Lenses in Delaying the Progression of Myopia: a Randomized Controlled TrialActive, not recruitingNCT07264361Not applicable1 country
- Efficacy and Safety of 0.01%, 0.03%, and 0.05% Atropine Eye Drops in Reducing Myopia ProgressionCompletedNCT07626892Phase 31 country
- Atropine Alone vs Atropine Plus Bifocal Spectacles for Myopia Control in ChildrenCompletedNCT07614113Not applicable1 country
- Choroidal Response to Novel Spectacle Lens to Control Myopia ProgressionActive, not recruitingNCT03818880Not applicable1 country
- Novel Lenses for Myopia Progression TrialActive, not recruitingNCT06563700Not applicable1 country
- Safety and Efficacy of Blue Star MAX-5 Lenses in Myopia ControlActive, not recruitingNCT06647160Not applicable1 country
- Stellest Lens Wear in Adult Progressing MyopesActive, not recruitingNCT06520124Not applicable1 country
- A Study of SHJ002 Sterile Ophthalmic Solution for Myopia ControlActive, not recruitingNCT06579287Phase 22 countries
- Myopia Progression With Freeform Myopia Control SpectaclesActive, not recruitingNCT06927388Not applicable1 country
- Double Helix Design Defocus Lens Spectacle (RACE) for Myopia ControlActive, not recruitingNCT05894382Not applicable1 country
- Clinical Evaluation of a Myopia Control Lens in Slowing Myopia ProgressionActive, not recruitingNCT05331378Not applicable1 country
- Impact of Digital Screen Time in Progression of Myopia in ChildrenActive, not recruitingNCT070558151 country
- Low-dose Atropine for Myopia Control in ChildrenActive, not recruitingNCT03865160Phase 2/31 country
- Kubota Glass Parameter Refinement StudyCompletedNCT06085430Not applicable1 country
- Effect of Virtual Reality-Based Visual Training for Myopia Control in ChildrenCompletedNCT06250920Not applicable1 country
- Clinical Evaluation of MyoCare in Europe (CEME)Active, not recruitingNCT05919654Not applicable1 country
- A Unified Index to Predict the Success Probability of Myopia ControlWithdrawnNCT05773118Not applicable
- Study of OT-101 in Treating MyopiaActive, not recruitingNCT04770610Phase 31 country
- Corneal Flap Transplantation for Macular Hole Repair of High MyopiaActive, not recruitingNCT05875909Not applicable1 country
- Adverse Events Related to Low Dose AtropineCompletedNCT056835351 country
- Myopia Prevention Through Monitoring and Motivating Outdoor Activities With SmartwatchesStatus unknownNCT05760911Not applicable
- Safety, Tolerability and Pharmacodynamics Evaluation of CBT-009 Eye DropCompletedNCT05372991Phase 1/21 country
- Optical Coherence Tomography Angiography Criteria Of The Choroidal Neovascular Membrane In Wet Age Related Macular Degeneration And In Pathological Myopia (Comparative Study).Status unknownNCT05562336
- Contact Lens and Myopia Control in Optometry School StudentsWithdrawnNCT04334369Not applicable1 country
- Myopia-control Efficacy by Peripheral Defocus Lens (PDL)Status unknownNCT05373693Not applicable1 country
- DIMS-myopia Progression ADN Axial Length GrowthCompletedNCT05300321Not applicable1 country
- Near Horizontal Heterophoria in Chinese ChildrenCompletedNCT050076261 country
- Repeated Low-Level Red-Light Therapy and Orthokeratology in Fast-progressing Myopia ControlStatus unknownNCT04722874Not applicable1 country
- Myopia Control With Orthokeratology Contact Lenses in SpainCompletedNCT04806763Not applicable