Multiple Organ Failure clinical trials

The registry lists 154 studies for Multiple Organ Failure across more than 10 countries. 43 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-23.

Studies

Recruiting first, then most recently updated. Showing 50 of 154 — search for more.

• FOUR-Based Modification of ICU Severity ScoresNot yet recruitingNCT078327731 country
• Metabolic and Functional Study of γδ T Cells in Critically Ill PatientsRecruitingNCT076808161 country
• Efferon LPS Hemoadsorption in Cardiac Surgery PatientsRecruitingNCT07532174Not applicable1 country
• AI-Based Precision Transfusion Prediction Model in Critically Ill PatientsNot yet recruitingNCT07762131
• Impact of Metabolite Supplementation to Restore Mitochondrial Dysfunction During Septic Shock: a Preclinical StudyRecruitingNCT042886351 country
• Hemoadsorpion in Patients With Septic Shock: Efficacy and Safety EvaluationNot yet recruitingNCT07661303Not applicable1 country
• ICU Background Early Awareness for Critical deterioratiONRecruitingNCT071194111 country
• Adding a Gastrointestinal Subscore to SOFA2 for Mortality Risk Assessment in the ICU: The SOFA2-GIS StudyNot yet recruitingNCT075862541 country
• Heterogeneity of Critical Illness: a Cohort StudyRecruitingNCT045025111 country
• Effect of oXiris Hemofilter Use in Septic Shock: A Multicenter Retrospective Cohort StudyRecruitingNCT075398831 country
• TDAP in Burn Patients (Group 2)Not yet recruitingNCT072236841 country
• Surgical Critical Care Initiative (SC2i) Tissue and Data Acquisition Protocol (TDAP) in Burn Patients Improving the Robustness and Generalizability of Post-burn Sepsis Prediction With the Post-Burn Sepsis Digital Twin. Group 1Not yet recruitingNCT072497621 country
• Mechanisms of Prognostic Regulation andPrecision Phenotype Ldentification in Severe Infections Driven by SpecializedPro-Resolving MediatorsNot yet recruitingNCT07353970
• Extracorporeal Blood Purification Using Oxiris for Septic Shock (EXPLORE Study)Not yet recruitingNCT07334327Not applicable
• Point-of-Care AI Assistance and Critical Care Outcomes: A Randomized TrialNot yet recruitingNCT07293078Phase 1/21 country
• Sivelestat Treatment for Postoperative Organ Protection in Type A Aortic DissectionNot yet recruitingNCT07156656Phase 41 country
• Study on the Establishment of a System for Early Warning and Prognostic Evaluation of Patients With Heat StrokeNot yet recruitingNCT051553581 country
• Can Gdf-15 Level Predict Progression to Multiple Organ Failure in Patients With Septic ShockEnrolling by invitationNCT068081001 country
• Impact of Fourier Transform Infrared Spectroscopy (FTIRS) in ICUsRecruitingNCT05872152Not applicable1 country
• Evaluation of the Efficiency of Intermittent Enteral Nutrition on Multi-organ Failure From Patients With Mechanical Ventilation in Intensive Care UnitRecruitingNCT06330610Not applicable1 country
• The Study Seeks to Determine Potential Correlations Between Ventilation and Hematological Alterations, Contributing to a Better Understanding of Its Physiological Effects and Optimizing Patient Management in Critical Care Settings.Not yet recruitingNCT070301141 country
• Rectal Indomethacin as Early Treatment for Acute Pancreatitis (INDOMAP Trial)RecruitingNCT03547232Phase 41 country
• Alveolar Dead Space as Predictor of Organ Failure in Severe SepsisNot yet recruitingNCT013157821 country
• Hemoperfusion in Critical Patients With Septic Multiorgan Dysfunction Syndrome.RecruitingNCT05044403Not applicable1 country
• High-flow Nasal Oxygenation for Apnoeic Oxygenation During Intubation of the Critically IllRecruitingNCT058831371 country
• Safety, Tolerability and Performance of the NucleoCapture Extracorporeal Therapeutic Apheresis Device in the Reduction of Circulating cfDNA/NETs in Subjects With PancreatitisNot yet recruitingNCT06566638Not applicable1 country
• Use of EBPT in Critically Ill Patients With AKI and/or Multiorgan FailureRecruitingNCT040332241 country
• Electronic Archive of Internal Medicine for the Treatment of Severe Organ Failure and Liver Transplantation-MITIGORecruitingNCT067815021 country
• Retrospective Analysis of Chest X-ray Severity Scoring System of COVID-19 PneumoniaRecruitingNCT051816961 country
• Safety and Efficacy of Fecal Microbiota TransplantationRecruitingNCT04014413Not applicable1 country
• OXiris for Abdominal SEptic Shock (OASES Study)Not yet recruitingNCT06504316Not applicable1 country
• Metabolic Reprogramming in Renal Tubular Cells in Acute Kidney Injury Following Severe TraumaRecruitingNCT061675121 country
• The Impact and Effect of Traditional Chinese Medicine Treatment on Organ Failure in Critically Ill PatientsRecruitingNCT06452966Not applicable1 country
• MultiStem® for Treatment of Trauma Induced Multiple Organ Failure/Systemic Inflammatory Response SyndromeRecruitingNCT04533464Phase 21 country
• Mechanisms of Multi-organ Failure in COVID-19RecruitingNCT043996031 country
• Burden, Mortality and Supply Costs in Intensive Care Unit PatientsRecruitingNCT040944281 country
• Intermittent ADVOS vs. Hemodialysis in Non-intensive Care Patients With Liver DysfunctionRecruitingNCT06129617Not applicable1 country
• The PRE-OP ENERGY TrialRecruitingNCT04015973Not applicable1 country
• Severe Sepsis/Septic Shock on Admission to the General Surgical ICURecruitingNCT013636351 country
• Acute Cardiac Dysfunction in Critical IllnesRecruitingNCT058605041 country
• European Registry for Hemadsorption in Sepsis With the Seraph FilterRecruitingNCT056080961 country
• Evaluation of the Effectiveness of Extracorporeal Methods for Removing Mediators of Systemic InflammationRecruitingNCT05182723Not applicable1 country
• Exosome of Mesenchymal Stem Cells for Multiple Organ Dysfuntion Syndrome After Surgical Repaire of Acute Type A Aortic DissectionNot yet recruitingNCT04356300Not applicable
• Dalargin for Prevention of Organ Disfunction in High-Risk Abdominal SurgeryCompletedNCT07404358Phase 31 country
• The Val-CARD TrialTerminatedNCT03825250Phase 1/21 country
• Disseminated Intravascular Coagulation (DIC) Score and Organ Dysfunction in Septic Shock PatientsCompletedNCT063631491 country
• Trial of Indication-Based Transfusion of Red Blood Cells in ECMOActive, not recruitingNCT05405426Not applicable3 countries
• Evaluating the Utility of RELiZORB™ for Treating Feeding Intolerance in Critically Ill Adults With Multi-Organ FailureActive, not recruitingNCT05710315Not applicable1 country
• TCF7L2 Polymorphisms Influence on Glycemic Control in ICU Patients With Organ FailureCompletedNCT030551691 country
• Artificial Intelligence for Ulinastatin Responder Outcome & Risk Assessment in CPBActive, not recruitingNCT075832901 country