Malaria, Falciparum: all 390 studies
Page 1 of 4. Open to participants first (35), then studies with results posted, then the rest; newest registration first within each.
- Ethiopian Antimalarial Therapeutic Efficacy Study 2026Not yet recruitingNCT07840898
- Safety and Immunogenicity of the Recombinant Malaria Vaccines in Healthy Adults Aged 18-50 YearsNot yet recruitingNCT07831226Phase 1
- Artemisia Annua Infusion for the Treatment of Asymptomatic Plasmodium Falciparum InfectionNot yet recruitingNCT07819825Phase 1
- Platform Study to Evaluate the Efficacy and Safety of Anti-malarial Agents in Participants With Uncomplicated Plasmodium Falciparum Malaria (Cohort C2)RecruitingNCT07811908Phase 2
- OPTIMAL LEAP: Optimizing Dihydroartemisinin-Piperaquine IPTsc Intervals to Advance Learning, Executive Function, Attendance, and Antimalarial Resistance Surveillance in Kenyan SchoolchildrenNot yet recruitingNCT07798583Phase 3
- Insecticide-Treated Baby Wraps for the Prevention of MalariaNot yet recruitingNCT07773350Not applicable
- Assessing Vaccine Effectiveness of R21/Matrix-M Across Malaria Transmission Settings (AVERT)RecruitingNCT07749911
- Challenge Trial of PfSPZ-LARC2 Vaccine in Burkina FasoNot yet recruitingNCT07730177Phase 1
- PfSPZ-LARC2 Vaccine in Women of Child-bearing Potential (WOCBP) in MaliRecruitingNCT07675785Phase 2
- First-in-Human Dose-escalation of GSK4425689A: Safety, Tolerability, and PK in Healthy AdultsRecruitingNCT07646353Phase 1
- Safety and Efficacy of Imatinib in Combination With Artemether-Lumefantrine for Uncomplicated MalariaRecruitingNCT07559370Phase 2
- Malaria CVD 36000; Gates INV090205Not yet recruitingNCT07558122Phase 1
- Safety and PK of MMV371 LAI in Healthy Adults and Adolescents in RwandaNot yet recruitingNCT07548021Phase 1
- A Phase 2A Study of a Novel Antimalarial Pyrrolidinamide in Adult Patients With Uncomplicated P. Falciparum MalariaNot yet recruitingNCT07545681Phase 2
- Assessing the Feasibility of Combining Dihydroartemisinin Piperaquine and Primaquine for Malaria Mass Drug Administration in High Endemic Communities in the Eastern Region of GhanaRecruitingNCT07389057Not applicable
- Field Trial of PfSPZ-LARC2 Vaccine in Burkinabe AdultsRecruitingNCT07385287Phase 2
- Perennial Malaria Chemoprevention in the Malaria Vaccine EraNot yet recruitingNCT07322068Phase 4
- R21/MM Dosing, Presentations, and PreservativesNot yet recruitingNCT07194668Phase 4
- A Study to Assess the Safety and Immunogenicity of a Vaccine Against Malaria in Healthy Children Aged 5-60 MonthsRecruitingNCT07036159Phase 2
- Single Ascending Dose Study to Assess the Safety, Tolerability and Pharmacokinetics of LAI MMV055 Alone and in Combination With MMV371 in Healthy ParticipantsRecruitingNCT07011511Phase 1
- An Observational Study to Assess Effectiveness and Safety of The R21/Matrix-M Malaria VaccineRecruitingNCT07009847
- Serological Testing and Treatment for Plasmodium Vivax Malaria: a Trial in Ethiopia and MadagascarRecruitingNCT06923592Phase 3
- Experimental Malaria Infection of Healthy Malaria-Naive Adults by Mosquito Bite With the Genetically Modified Plasmodium Falciparum NF54/iGP3 GAPNot yet recruitingNCT06881732Phase 1
- Safety, Tolerability and Efficacy of PfSPZ-LARC2 Vaccine Against CHMI in Malaria-Naïve AdultsRecruitingNCT06862453Phase 1
- The Impact RTS,S/AS01 Vaccine in School Aged Children RTS,S/AS01 Malaria Vaccine in School Aged ChildrenNot yet recruitingNCT06424002Phase 4
- Seasonal Malaria Chemoprevention Rapid Assessment Study MozambiqueNot yet recruitingNCT06337253Phase 4
- Durability of Protection After Single Immunisation With GA2 Sporozoites (CoGA-Rechallenge)Not yet recruitingNCT06293339Phase 1
- Mass Vaccine and Drug Administration, BangladeshRecruitingNCT06068530Phase 4
- A Study to Determine Safety, Tolerability, and Pharmacokinetics of Different Orally Administered Regimens of the Combination ZY19489-Ferroquine in Adult Asymptomatic Plasmodium Falciparum CarriersRecruitingNCT05911828Phase 1
- Addressing Asymptomatic Plasmodium Reservoirs to Accelerate Malaria Elimination and Eradication in Rwanda.Not yet recruitingNCT05801198Phase 2
- Platform Study to Evaluate the Efficacy and Safety of Anti-malarial Agents in Patients With Uncomplicated Plasmodium Falciparum MalariaRecruitingNCT05750628Phase 2
- Platelet-Directed Whole Blood Transfusion Strategy for MalariaRecruitingNCT05711485Not applicable
- DON in Pediatric Cerebral MalariaRecruitingNCT05478720Phase 1/2
- Effect of Paracetamol on Kidney Function in Severe MalariaRecruitingNCT04251351Phase 3
- Laboratory Evaluation of Pregnancy Malaria Vaccine Candidates/In-vitro Testing of Pregnancy Malaria Vaccine CandidatesRecruitingNCT02471378
- Platform Study to Evaluate the Efficacy and Safety of Anti-malarial Agents in Participants With Uncomplicated Plasmodium Falciparum Malaria (Cohort B2)CompletedNCT07235033Phase 2Results posted
- A Clinical Trial to Evaluate the Safety, Efficacy and Immune Responses After Vaccination With an Investigational RNA-based Vaccine Against MalariaCompletedNCT06069544Phase 1/2Results posted
- Phase 1b MMV367 PK/PD and Safety in Healthy Adult Volunteers Experimentally Infected With Blood Stage P. FalciparumCompletedNCT05979207Phase 1Results posted
- Efficacy, Safety, and PK of M5717 in Combination With Pyronaridine as Chemoprevention in Adults and Adolescents With Asymptomatic Plasmodium Falciparum Infection (CAPTURE-2)CompletedNCT05974267Phase 2Results posted
- Phase IIa Proof of Concept Study of M5717-Pyronaridine in Adults and Adolescents With Acute Uncomplicated Plasmodium Falciparum Malaria (CAPTURE 1)CompletedNCT05689047Phase 2Results posted
- A Phase 1 Trial of PfSPZ Vaccine in Healthy Adults to Determine Safety, Tolerability and Efficacy Against Heterologous CHMITerminatedNCT05604521Phase 1Results posted
- Safety and Immune Responses After Vaccination With an Investigational RNA-based Vaccine Against MalariaCompletedNCT05581641Phase 1Results posted
- First-in-Human Study to Assess the Safety, Tolerability and Pharmacokinetics of MMV367CompletedNCT05507970Phase 1Results posted
- A Study of the Plasmodium Falciparum Malaria Vaccine Candidate Pfs48/45 in Matrix-M Adjuvant in the UKTerminatedNCT05400746Early Phase 1Results posted
- Pyronaridine in Healthy Adult Participants Infected With Blood Stage MalariaCompletedNCT05287893Phase 1Results posted
- Safety and Immunogenicity of the Malaria Vaccine, R21/MatrixM, in Healthy Thai AdultsCompletedNCT05252845Phase 2Results posted
- Study of the Transmission-Blocking Vaccine Pfs230D1-EPA/Matrix-M Against Malaria in Adults in MaliCompletedNCT05135273Phase 1Results posted
- PfSPZ Vaccine Trial in Malian ChildrenCompletedNCT04940130Phase 2Results posted
- Safety and Efficacy of R0.6C VaccineCompletedNCT04862416Phase 1Results posted
- Efficacy of SJ733 in Adults With Uncomplicated Plasmodium Falciparum or Vivax MalariaCompletedNCT04709692Phase 2Results posted
- Efficacy, Safety and Tolerability of KAF156 in Combination With Lumefantrine Solid Dispersion Formulation (LUM-SDF) in Pediatric Population With Uncomplicated Plasmodium Falciparum MalariaCompletedNCT04546633Phase 2Results posted
- Seasonal Malaria Vaccination (RTS,S/AS01) and Seasonal Malaria Chemoprevention (SP/AQ) Extension StudyCompletedNCT04319380Phase 3Results posted
- Study in Blood Stage Malaria Infection After DVI of Cryopreserved P. Falciparum (NF54 Strain) SporozoitesCompletedNCT04310085Phase 1Results posted
- Pharmacokinetics, Safety, Tolerability and Efficacy of a New Artemether-lumefantrine Dispersible Tablet in Infants and Neonates <5 kg Body Weight With Acute Uncomplicated Plasmodium Falciparum MalariaTerminatedNCT04300309Phase 2/3Results posted
- Safety, Tolerability, and Pharmacokinetics and Pharmacodynamics of TB31FCompletedNCT04238689Phase 1Results posted
- TES of Artemether-lumefantrine for Pf and Chloroquine for Pv in the Philippines From 2013-2014CompletedNCT04222088Results posted
- Evaluate the Infectivity Equivalence of Current and New Lots of Plasmodium Falciparum Strain NF54CompletedNCT03882528Phase 1Results posted
- Safety and Efficacy of NF135 CPS ImmunizationTerminatedNCT03813108Not applicableResults posted
- Study to Investigate the Clinical and Parasiticidal Activity and Pharmacokinetics of Different Doses of Artefenomel and Ferroquine in Patients With Uncomplicated Plasmodium Falciparum MalariaCompletedNCT03660839Phase 2Results posted
- Safety, Tolerability, Immunogenicity and Protective Efficacy of PfSPZ Vaccine and PfSPZ-CVac in Indonesian Adults Against Naturally-Transmitted MalariaCompletedNCT03503058Phase 2Results posted
- Controlled Human Malaria Infection Model for Evaluation of Transmission-blocking Interventions - Study 2CompletedNCT03454048Not applicableResults posted
- Extended Duration Artemether-lumefantrine Treatment for Malaria in ChildrenCompletedNCT03453840Phase 4Results posted
- Study to Compare the Triple ACT AL+AQ With the ACT AL in Cambodia and VietnamCompletedNCT03355664Phase 3Results posted
- Safety of KAE609 in Adults With Uncomplicated Plasmodium Falciparum Malaria.CompletedNCT03334747Phase 2Results posted
- Enhancing Preventive Therapy of Malaria In Children With Sickle Cell Anemia in East Africa (EPiTOMISE)CompletedNCT03178643Phase 4Results posted
- Efficacy and Safety of KAF156 in Combination With LUM-SDF in Adults and Children With Uncomplicated Plasmodium Falciparum MalariaCompletedNCT03167242Phase 2Results posted
- Seasonal Malaria Vaccination (RTS,S/AS01) and Seasonal Malaria Chemoprevention (SP/AQ)CompletedNCT03143218Phase 3Results posted
- Safety and Protective Efficacy of Pb(PfCS@UIS4)CompletedNCT03138096Phase 1/2Results posted
- MMV390048 POC in Patients With P. Vivax and P. Falciparum MalariaTerminatedNCT02880241Phase 2Results posted
- SJ733 Induced Blood Stage Malaria Challenge StudyCompletedNCT02867059Phase 1Results posted
- Methylene Blue Against Falciparum Malaria in Burkina FasoCompletedNCT02851108Phase 2Results posted
- Artemether-lumefantrine for Treatment of P. Falciparum Malaria in BrazilCompletedNCT02600767Not applicableResults posted
- To Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of a Single Dose Regimen of Ferroquine and Artefenomel in Adults and Children With Uncomplicated Plasmodium Falciparum MalariaTerminatedNCT02497612Phase 2Results posted
- Evaluate the Safety and Efficacy of Plasmodium Falciparum Malaria Protein 010 (FMP010) Administered With Adjuvant AS01BCompletedNCT02458092Phase 1Results posted
- MMV390048 Against Early Plasmodium Falciparum Blood Stage Infection in Healthy ParticipantsTerminatedNCT02281344Phase 1Results posted
- Epidemiology Study of Malaria Transmission Intensity in Sub-Saharan AfricaCompletedNCT02251704Phase 4Results posted
- Phase II Efficacy Study of Artefenomel & Piperaquine in Adults & Children With P. Falciparum Malaria.CompletedNCT02083380Phase 2/3Results posted
- Efficacy, Safety and Pharmacokinetics of Artemether-lumefantrine Dispersible Tablet in the Treatment of Malaria in Infants < 5 kgCompletedNCT01619878Phase 2/3Results posted
- Phase II Dose-ranging Study of Pyronaridine/Artesunate in Adults Patients With Plasmodium Falciparum MalariaCompletedNCT01594931Phase 2Results posted
- Trial of a Falciparum Malaria Protein (FMP012), E. Coli-expressed PfCelTOS, in Healthy Malaria-Naive AdultsCompletedNCT01540474Phase 1Results posted
- Superiority of ArTiMist Versus Quinine in Children With Severe MalariaCompletedNCT01258049Phase 3Results posted
- Efficacy, Tolerability, PK of OZ439 in Adults With Acute, Uncomplicated P.Falciparum or Vivax Malaria Mono-infectionCompletedNCT01213966Phase 2Results posted
- Evaluate Azithromycin Plus Chloroquine And Sulfadoxine Plus Pyrimethamine Combinations For Intermittent Preventive Treatment Of Falciparum Malaria Infection In Pregnant Women In AfricaTerminatedNCT01103063Phase 3Results posted
- Efficacy of ArTiMist™ in ChildrenCompletedNCT01047436Phase 2Results posted
- A Study to Investigate the Safety, Tolerability and Pharmacokinetics of OZ439 in Healthy Male and Female SubjectsCompletedNCT00928083Phase 1Results posted
- Azithromycin Plus Chloroquine Versus Artemether-Lumefantrine For The Treatment Of Uncomplicated P. Falciparum Malaria In Children In AfricaCompletedNCT00677833Phase 2/3Results posted
- Pyronaridine Artesunate 3:1 Granule Formulation vs. Coartem© Crushed Tablets in P. Falciparum Malaria Pediatric PatientsCompletedNCT00541385Phase 3Results posted
- Phase II AMA-1 Malaria Vaccine FMP2.1/AS02A Trial in MaliCompletedNCT00460525Phase 2Results posted
- Pyronaridine Artesunate (3:1) Versus Coartem® in P Falciparum Malaria PatientsCompletedNCT00422084Phase 3Results posted
- Pyronaridine - Artesunate (3:1) Versus Mefloquine Plus Artesunate in Plasmodium Falciparum Malaria PatientsCompletedNCT00403260Phase 3Results posted
- Phase I Pediatric FMP2.1/AS02A Trial in MaliCompletedNCT00358332Phase 1Results posted
- FMP2.1/AS02A: Rabies Vaccine Malaria-Experienced Adults in Bandiagara, MaliCompletedNCT00349713Phase 1Results posted
- Pyronaridine and Artesunate (3:1) in Children With Acute Uncomplicated Plasmodium Falciparum MalariaCompletedNCT00331136Phase 2Results posted
- Phase 1 Trial of a Malaria Vaccine in Young Kenyan ChildrenCompletedNCT00317473Phase 1Results posted
- Phase I/II Trial of a Malaria Vaccine in Adults Living in the United States of AmericaCompletedNCT00312702Phase 1/2Results posted
- Phase I/II Trial of a Malaria Vaccine in Adults Living in the United States of AmericaCompletedNCT00312663Phase 1/2Results posted
- A Three Day Trial of Azithromycin Plus Chloroquine for the Treatment of Uncomplicated Plasmodium Falciparum MalariaCompletedNCT00282919Phase 2Results posted
- Double-blind, Randomized, Controlled Study of Safety, Immunogenicity and Efficacy of a Candidate Malaria VaccineCompletedNCT00223990Phase 2Results posted
- Controlled Human Malaria Infection by Mosquito Bites Using a Local Strain of Plasmodium FalciparumCompletedNCT07816497Phase 1
- Platform Study to Evaluate the Efficacy and Safety of Anti-malarial Agents in Participants With Uncomplicated Plasmodium Falciparum Malaria (Cohort B1)CompletedNCT07811882Phase 2