Malaria, Falciparum: all 390 studies
Page 3 of 4. Open to participants first (35), then studies with results posted, then the rest; newest registration first within each.
- Targeted Active Case Detection Among High Risk Populations in Southern Lao Peoples Democratic RepublicCompletedNCT03783299Phase 4
- Efficacy and Safety of Artesunate + Amodiaquine With SLD of Primaquine for Treatment of Falciparum Malaria in ZanzibarCompletedNCT03773536Phase 4
- Efficacy of Artesunate + Amodiaquine Versus Artemether-lumefantrine for Falciparum Malaria in Zanzibar, 2005CompletedNCT03768908Phase 4
- Tolerability and Efficacy of Artemether-Lumefantrine Versus Artesunate + Amodiaquine in ZanzibarCompletedNCT03764527Phase 4
- Drug Combinations of Atovaquone-Proguanil (AP) With ACTStatus unknownNCT03726593Phase 4
- Triple Antimalarial Combination to Accelerate the Parasite Clearance and to Prevent the Selection of Resistant ParasitesStatus unknownNCT03697668Phase 2
- Effectiveness and Safety of Intermittent Preventive Treatment for Malaria Using Either Dihydroartemisinin-piperaquine or Artesunate-amodiaquine in Reducing Malaria Related Morbidities and Improving Cognitive Ability in School-aged Children in TanzaniaCompletedNCT03640403Phase 3
- A Study to Determine if a New Malaria Vaccine is Safe and Induces Immunity Among Kenyan Adults, Young Children and InfantsCompletedNCT03580824Phase 1/2
- Evaluation of the Performance of a hsRDT Versus cRDT in Reactive Case Detection of Malaria InfectionsStatus unknownNCT03511443Not applicable
- Clinical Performance of the Histidine Rich Protein 2 (HRP2) Highly Sensitive Rapid Diagnostic Test (HS-RDT) for Malaria Diagnosis in Pregnant Women in Papua New GuineaCompletedNCT03462615
- Safety and Immunogenicity of ChAd63 RH5 and MVA RH5 in Adults, Young Children and Infants Living in TanzaniaCompletedNCT03435874Phase 1
- Efficacy and Safety of ASAQ and PD for the Treatment of Uncomplicated Falciparum Malaria in Mainland TanzaniaCompletedNCT03431714Phase 4
- Study to Evaluate Safety, Immunogenicity and Efficacy of PfSPZ Vaccine in HIV Negative and HIV Positive Tanzanian AdultsCompletedNCT03420053Phase 1
- Prospective Evaluation of an RDT to Screen for Gambiense HAT and Diagnose P. Falciparum MalariaWithdrawnNCT03394976
- "Prolonging the Therapeutic Life Span of Artemisinin-based Combination Therapies (ACT) in Bagamoyo District, Tanzania"CompletedNCT03241901Phase 4
- Cohort Event Monitoring Study of Pyramax®CompletedNCT03201770Phase 4
- Chemoprotective Activity of MMV390048 in PfSPZ Challenge ModelWithdrawnNCT03195387Phase 1
- Non-specific Effects of Vaccination on Mortality and MorbidityStatus unknownNCT03176719
- Evaluation of Community-based Mass Screening and Treatment for Malaria in Western KenyaCompletedNCT02987270Phase 3
- Molecular Surveillance of Artemisinin Resistance Malaria in MyanmarCompletedNCT02792816
- A Microdose Study in Healthy Subjects to Describe Intravenous Pharmacokinetics of GSK3191607CompletedNCT02737007Phase 1
- Artemether-lumefantrine Resistance Monitoring in Children With Uncomplicated Plasmodium Falciparum Malaria in MaliCompletedNCT02645604
- In Vivo Efficacy of Artemether-Lumefantrine and Artesunate-Amodiaquine for Uncomplicated P. Falciparum MalariaCompletedNCT02637128Phase 4
- Effect of Imatinib on Suppression of Malaria Parasites in Patients With Uncomplicated Plasmodium Falciparum MalariaCompletedNCT02614404Phase 1
- Efficacy, Safety, and Tolerability of Dihydroartemisinin-piperaquine + Mefloquine Compared to Dihydroartemisinin-piperaquine or Artesunate-mefloquine in Patients With Uncomplicated Falciparum Malaria in CambodiaCompletedNCT02612545Phase 1
- Effectiveness of KAE609 in Reducing Asexual & Sexual Blood-stage P.Falciparum Infection & Infectivity to MosquitosTerminatedNCT02543086Phase 1
- Arterolane-PQP Versus DHA-PQP in Uncomplicated Falciparum Malaria in Eastern MyanmarWithdrawnNCT02461186Phase 2/3
- A Study by the Tracking Resistance to Artemisinin Collaboration (TRAC)CompletedNCT02453308Phase 2/3
- Liberia Insecticide Treated Durable Wall Linings Study: Protocol for a Cluster Randomised Trial (DL)CompletedNCT02448745Not applicable
- Safety and Tolerability of Low Dose PrimaquineCompletedNCT02434952Phase 4
- Evaluating the Efficacy of Artesunate-mefloquine and the Relative Roles of Resistance Genetic MarkersCompletedNCT02427360
- Efficacy and Safety of Pyronaridine-artesunate for the Treatment in Uncomplicated Falciparum MalariaCompletedNCT02389439Phase 2
- Study of the Safety and Immunogenicity of Pfs230D1M-EPA/Alhydrogel and Pfs25M-EPA/Alhydrogel , a Transmission Blocking Vaccine Against Plasmodium Falciparum Malaria, in Adults in the U.S. and MaliCompletedNCT02334462Phase 1
- Mass Drug Administration With Dihydroartemisinin + Piperaquine for Reducing Malaria in Southern ZambiaCompletedNCT02329301Not applicable
- Artemisinin-based Combination Therapy for Treatment of Plasmodium Falciparum Malaria in North Sumatera, IndonesiaCompletedNCT02325180Phase 4
- A Safety and Efficacy Study of Concomitant Administration of ChAd63/MVA ME-TRAP + RTS,SCompletedNCT02252640Phase 1/2
- Effect of Plasmodium Falciparum Exposure and Sickle Cell Trait on Infection Rates and Kinetics After IV Administration of PfSPZ ChallengeCompletedNCT02237586Phase 1
- Evaluation of Fosmidomycin and Piperaquine in the Treatment of Acute Falciparum MalariaStatus unknownNCT02198807Phase 2
- A Phase Ia Clinical Trial to Assess the Safety and Immunogenicity of New Plasmodium Falciparum Malaria Vaccine Candidates ChAd63 RH5 Alone and With MVA RH5CompletedNCT02181088Phase 1
- Dose Escalation, Randomized Controlled Trial to Evaluate the Safety, Immunogenicity and Efficacy of Intravenously Administered Attenuated Plasmodium Falciparum Sporozoite Vaccine (PfSPZ Vaccine) in Tanzanian AdultsCompletedNCT02132299Phase 1
- DSM265 Phase IIa Investigation Treating Plasmodium Falciparum or VivaxCompletedNCT02123290Phase 2
- Safety and Protective Efficacy of Intravenous Immunization With Cryopreserved Plasmodium Falciparum Sporozoites Under ChemoprophylaxisCompletedNCT02115516Phase 1
- Efficacy of Artemether/Lumefantrine for the Treatment of Uncomplicated Malaria.CompletedNCT02089841Phase 4
- Assessment of Artesunate/Mefloquine in the Peruvian AmazonCompletedNCT02084602Phase 4
- A Phase I/IIa Study of the Safety, Immunogenicity and Efficacy of FMP2.1/AS01B, an Asexual Blood-Stage Vaccine for Plasmodium Falciparum MalariaCompletedNCT02044198Phase 1/2
- Safety and Immunogenicity of Recombinant Pichia Pastoris AMA1-DiCo Candidate Malaria Vaccine With GLA-SE and Alhydrogel ® as Adjuvant in Healthy Malaria Non-Exposed European and Malaria Exposed African AdultsCompletedNCT02014727Phase 1
- Malaria in Early Life StudyCompletedNCT02001428Not applicable
- A Pharmacokinetic/Pharmacodynamic Study of Eurartesim Dispersible Formulation in Infants With P.Falciparum MalariaCompletedNCT01992900Phase 2
- Artemether/ Lumefantrine: A Study of the Effect of Local Food on Pharmacokinetics and Population PharmacokineticsStatus unknownNCT01944189Phase 4
- Safety, Tolerability, Pharmacokinetics and Efficacy of ARCOCompletedNCT01930331Phase 4
- A Safety and Efficacy Study of ChAd63/MVA METRAP + RTS,SCompletedNCT01883609Phase 1/2
- Targeted Chemo-elimination (TCE) of MalariaCompletedNCT01872702Not applicable
- Antimalarial Drug Resistance With Assessment of Transmission Blocking ActivitySuspendedNCT01849640Not applicable
- Rapid Diagnostic Tests for Assessment of Initial Clearance and Detection of Recurrent Malaria InfectionsCompletedNCT01843764
- Malaria Transmission Studies in MaliCompletedNCT01829737
- Immunization With Plasmodium Falciparum Sporozoites Under Chloroquine or Chloroquine/Azithromycin ProphylaxisWithdrawnNCT01783340Phase 1/2
- Efficacy of Three ACTs for the Treatment of Falciparum Malaria in Maradi NigerCompletedNCT01755559Phase 4
- A Phase I/IIa Sporozoite Challenge Study to Assess the Efficacy of Candidate Combination Malaria Vaccine Approaches Using the ChAd63 and MVA Vectors Encoding the Antigens ME-TRAP, CS and AMA1CompletedNCT01739036Phase 1/2
- Artemisinin-resistant Malaria in CambodiaCompletedNCT01736319
- Impact of Insecticide Resistance on Vector ControlStatus unknownNCT01713517Phase 4
- SPK Study in AfghanistanCompletedNCT01707199Not applicable
- Re-exposure of Human Volunteers to a Heterologous Strain of P. Falciparum SporozoitesCompletedNCT01660854Not applicable
- Efficacy of Artesunate-Mefloquine Combination Therapy in Trat Province, ThailandCompletedNCT01659281Not applicable
- Comparison of Three Plasmodium Falciparum Isolates in a Controlled Human Malaria InfectionCompletedNCT01627951Not applicable
- A Challenge Study to Assess the Protective Efficacy of Two Malaria Vaccine CandidatesCompletedNCT01623557Phase 1/2
- Efficacy Study of Amodiaquine-Artesunate and Artemether-Lumefantrine for the Treatment of Uncomplicated MalariaCompletedNCT01567423Not applicable
- Safety and Preliminary Efficacy of the Malaria Vaccine Candidates Falciparum Merozoite Protein-1 (FMP1) and SmithKlineBeecham (SKBB) Candidate Malaria Vaccine RTS,SCompletedNCT01556945Phase 1/2
- Evaluation of Fosmidomycin and Clindamycin in the Treatment of Acute Uncomplicated P.Falciparum Malaria in ChildrenCompletedNCT01464138Phase 2
- Fosmidomycin and Azithromycin for Acute Uncomplicated Plasmodium Falciparum Malaria (P. Malaria) in AdultsStatus unknownNCT01464125Phase 2
- Sevuparin/DF02 as an Adjunctive Therapy in Subjects Affected With Uncomplicated Falciparum MalariaTerminatedNCT01442168Phase 1/2
- Efficacy and Safety of Artesunate-amodiaquine-methylene for Malaria Treatment in ChildrenCompletedNCT01407887Phase 2
- Azithromycin Combination Therapy for the Treatment of Severe MalariaCompletedNCT01374126Phase 2
- Evaluation of the Gametocytocidal Efficacy and Safety of Primaquine in Uncomplicated Falciparum Malaria in UgandaCompletedNCT01365598Phase 3
- Evaluation of Fosmidomycin and Clindamycin in the Treatment of Acute Uncomplicated Plasmodium Falciparum MalariaStatus unknownNCT01361269Phase 2
- Tracking Resistance to Artemisinin (TRAC)CompletedNCT01350856Phase 4
- Efficacy of Artemether-lumefantrine, Artesunate-amodiaquine and Dihydroartemisinin-piperaquine for the Treatment of Uncomplicated Plasmodium Falciparum Malaria in MalawiCompletedNCT01326754Not applicable
- Time to Become Negative of Three Rapid Diagnostic Tests for MalariaCompletedNCT01325974
- Experimental Human Malaria Infection After Immunization With Plasmodium Falciparum Sporozoites Under Chloroquine ProphylaxisCompletedNCT01236612Not applicable
- Food Interaction Study on the Pharmacokinetics of Eurartesim™ (DHA and PQP)in Healthy Male Adult VolunteersCompletedNCT01222962Phase 1
- A Pharmacokinetic (PK) Trial in Healthy Asian and Caucasian Volunteers Investigating the PK Profile of Eurartesim™CompletedNCT01222949Phase 1
- Immunization With Different Doses of Plasmodium Falciparum Sporozoites Under Chloroquine ProphylaxisCompletedNCT01218893Not applicable
- Efficacy of Artesunate-amodiaquine (AS-AQ) in Children With Malaria and Severe Acute Malnutrition, Madaoua, Niger 2010WithdrawnNCT01204411Phase 4
- EP1300 Polyepitope DNA Vaccine Against Plasmodium Falciparum MalariaCompletedNCT01169077Phase 1
- Iron Absorption and Utilization in Adolescents Infected With Malaria Parasites, Hookworms or SchistosomaCompletedNCT01163877Not applicable
- Pilot Study to Estimate the Burden and Distribution of Plasmodium Falciparum Malaria in Kalifabougou, Mali in Preparation for a Prospective Cohort Study of Naturally-Acquired Malaria ImmunityCompletedNCT01160562
- Effectiveness of the Association Artesunate and Mefloquine in the Treatment of Malaria by Plasmodium FalciparumCompletedNCT01144702Phase 2/3
- Artesunate+Sulfadoxine-Pyrimethamine for the Treatment of Uncomplicated Falciparum MalariaCompletedNCT01115439
- Study of Iron Absorption and Utilization in Asymptomatic MalariaCompletedNCT01108939Early Phase 1
- Safety Study on the Effect of Eurartesim™ on QT/QTc Interval Compared to Riamet in Healthy VolunteersCompletedNCT01103830Phase 1
- Assessing the Efficacy of Artemisinin Combination Therapies for Treatment of Uncomplicated Malaria Infection in ChildrenCompletedNCT01082705Phase 3
- Safety and Effectiveness of Artemisinin-based Combination Therapies (ACTs) With Repeated Treatments for Uncomplicated Falciparum Malaria Over a Three-year PeriodStatus unknownNCT01038063Phase 4
- Trial to Assess the Efficacy of Malaria Vaccine PfCS 102CompletedNCT01031524Phase 1/2
- EBA-175 RII-NG Malaria Vaccine Administered Intramuscularly in Semi-immune AdultsCompletedNCT01026246Phase 1
- Extended-dose Chloroquine (ECQ) for Resistant Falciparum Malaria Among Afghan Refugees in PakistanCompletedNCT01019408Phase 4
- Artemether-lumefantrine (AL) Versus Artesunate + Amodiaquine (ASAQ) for the Treatment of Uncomplicated Falciparum Malaria in Burkina FasoCompletedNCT01017770Phase 4
- A Study to Assess Safety, Immunogenicity and Parasite Growth Inhibition of an Asexual Blood Stage Vaccine for P. Falciparum MalariaCompletedNCT00984763Phase 1/2
- Phase 1 Study of the Safety and Immunogenicity of a Malaria Transmission-blocking Pfs25-Pfs25 Conjugate VaccineWithdrawnNCT00977899Phase 1
- Trial of Artesunate Combination Therapy in PakistanCompletedNCT00959517Phase 2
- Therapeutic Efficacy Study of Pyrimethamine/Sulfdoxine (Fansidar®) for the Treatment of Uncomplicated Falciparum Malaria in the Peruvian AmazonCompletedNCT00951106Not applicable
- Artemisone for the Treatment of Uncomplicated Falciparum Malaria in Western CambodiaWithdrawnNCT00936767Phase 2/3