Lichen Planus clinical trials
The registry lists 74 studies for Lichen Planus across more than 10 countries. 15 are recruiting or about to start. 42 of them are mainly about Lichen Planus (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09. Counting its narrower condition Lichen Planus, Oral too: 208 studies, 41 open.
Get an email when these change. Save the Lichen Planus studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Who runs them
Mayo Clinic (3) · Massachusetts General Hospital (2) · Institut Pasteur (2) · Novartis Pharmaceuticals (2) · Cairo University (2) · Erasmus Medical Center (2) · Aaron R. Mangold (2) · Medical University of Graz (2)
What is being tested here
Drugs under test in Lichen Planus studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Topical Corticosteroid | 1 | 0 | 2 |
| Methotrexate | 1 | 0 | 1 |
| Acitretin | 1 | 0 | 1 |
| GIA632 | 1 | 0 | 1 |
| Delgocitinib | 1 | 0 | 1 |
| PF-06700841 | 1 | 1 | 1 |
| Nemolizumab | 1 | 0 | 1 |
| Steroids | 1 | 0 | 1 |
| Baricitinib | 0 | 0 | 2 |
| Apremilast | 0 | 0 | 2 |
Drug classes tested here JAK inhibitors 2 open · Tyrosine kinase inhibitors (TKIs) 2 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 5
- Apr 2027Efficacy of Clobetasol Vs Intralesional Triamcinolone in Lichen Planus Treatment · Noor Aziz
- Apr 2027Safety and Biomarker Responses of Delgocitinib (JAK1,2,3/TYK2 Inhibitor) in Central Centrifugal Cicatricial Alopecia and Lichen Planopilaris · Icahn School of Medicine at Mount Sinai
- Apr 2027Widefield Fluorescence and Reflectance Imaging Systems and Oral Tissue Samples in Monitoring Participants at Risk for Developing Oral Cancer · M.D. Anderson Cancer Center
- May 2027Vaginal Ecosystem and Network in the United States Study · Vaginal Biome Science
- Jun 2027Nemolizumab to Treat Lichen Planopilaris, a Noncontrolled, Prospective, Pilot Study. · The Skin Center Dermatology Group
Who these studies take
Of the 12 Lichen Planus studies recruiting now, 6 (50%) set no upper age limit and 3 (25%) stop at 75 or younger. 1 (8%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 3 (25%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (8%) | 1 (8%) |
| 18 | 10 (83%) | 10 (83%) |
| 30 | 12 (100%) | 12 (100%) |
| 40 | 12 (100%) | 12 (100%) |
| 50 | 12 (100%) | 12 (100%) |
| 65 | 10 (83%) | 10 (83%) |
| 75 | 9 (75%) | 9 (75%) |
| 85 | 7 (58%) | 7 (58%) |
Across all 74 studies, recruiting or not: 20% stop at 75 or younger and 12% at 65; 12% take children; 12% are for women only and 0% for men only; 31% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Lichen Planus studies take
Of 16 phase 2 interventional studies under Lichen Planus, half reached primary completion within 16 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 2 | 16 mo12–28 · 16 studies | — | — |
| Interventional, no phase | 25 mo8–42 · 15 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 74. Browse all 74 → or search them.
- A Study to Assess the Efficacy and Safety of GIA632 Across a Range of Doses in Participants With Moderate to Severe Cutaneous Lichen PlanusRecruitingNCT07775924Phase 24 countries
- Determinants of Chronic Inflammatory Skin Disease TrajectoriesRecruitingNCT059281691 country
- Safety and Biomarker Responses of Delgocitinib (JAK1,2,3/TYK2 Inhibitor) in Central Centrifugal Cicatricial Alopecia and Lichen PlanopilarisRecruitingNCT07487948Phase 21 country
- A Phase 2/3 Study of Brepocitinib in Adults With Lichen PlanopilarisRecruitingNCT07532603Phase 2/34 countries
- Efficacy of Clobetasol Vs Intralesional Triamcinolone in Lichen Planus TreatmentNot yet recruitingNCT07666620Phase 41 country
- Identification of Cutaneous and Blood Biomarkers Predictive of Response to Systemic Treatments During Chronic Inflammatory Skin DiseasesRecruitingNCT065994111 country
- Photobiomodulation, Photodynamic Therapy, and Clobetasol in the Treatment of Oral Lichen Planus.RecruitingNCT07278999Not applicable1 country
- Nemolizumab to Treat Lichen Planopilaris, a Noncontrolled, Prospective, Pilot Study.RecruitingNCT07396168Phase 41 country
- The Efficacy of Tranexamic Acid in the Treatment of Lichen Planus Pigmentosus and Erythema Dyschromicum PerstansRecruitingNCT04233749Phase 21 country
- Vaginal Ecosystem and Network in the United States StudyEnrolling by invitationNCT064727652 countries
- Cellular and Molecular Biomarkers in Patients With Lichen PlanusRecruitingNCT06451744Not applicable1 country
- Systemic Treatment Options for Generalized Lichen PlanusNot yet recruitingNCT06739551Phase 21 country
- The Effectiveness of Hydroxychloroquine Versus Methotrexate in the Treatment of Lichen Planopilaris in Routine Clinical Care: a Patient Preference TrialRecruitingNCT065127531 country
- Treatment Of Oral Lichen PlanusRecruitingNCT06327620Not applicable1 country
- Assessment Of Serum And Tissue Levels Of Cold-Inducible RNA-Binding Protein In Patients With Lichen PlanusRecruitingNCT062601891 country
- Efficacy and Safety of Baricitinib in Oral Lichen Planus: a Proof-of-Concept StudyCompletedNCT06158113Phase 21 country
- Widefield Fluorescence and Reflectance Imaging Systems and Oral Tissue Samples in Monitoring Participants at Risk for Developing Oral CancerActive, not recruitingNCT00542373Not applicable1 country
- Identification of Oral Lesions Through an Autofluorescence SystemCompletedNCT05942794Not applicable1 country
- Treatment Outcomes and Patient Satisfaction of Oral Lichen Planus TreatmentCompletedNCT06988527Phase 21 country
- Ritlecitinib for Cicatricial AlopeciaCompletedNCT05549934Phase 21 country
- Mucosal and Nasal Involvement and Their Correlation With Smell and Taste Functions in Lichen Planus PatientsCompletedNCT075707061 country
- Koebner's Phenomenon in Psoriasis and Lichen PlanusWithdrawnNCT06021405Not applicable
- Efficacy and Safety of add-on Apremilast Versus add-on Methotrexate in Patients With Oral Lichen PlanusCompletedNCT06260904Phase 41 country
- Biomarkers for Oral CancerCompletedNCT003414971 country
- Implication of Human Papillomavirus (HPV) in Lichen Physiopathology in Human (HPVLichen)CompletedNCT02761122Not applicable1 country
- A Study of Deucravacitinib to Treat LPP and FFACompletedNCT06091956Phase 21 country
- Effectiveness and Safety of Tofacitinib in Patients With Recalcitrant Frontal Fibrosing Alopecia : A Pilot StudyCompletedNCT06202560Not applicable1 country
- Laser Therapy in Women With Lichenoid DisordersCompletedNCT04697563Not applicable1 country
- Study of the Characteristics of Pruritus in Patients With Frontal Fibrosing Alopecia or Lichen Planus PilarisTerminatedNCT057611581 country
- A Study to Assess the Efficacy, Safety, and Tolerability of KPL-716 in Reducing Pruritus in Chronic Pruritic DiseasesCompletedNCT03858634Phase 21 country
- A Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Cutaneous Lichen PlanusCompletedNCT05593432Phase 22 countries
- a Retrospective Study on the Systemic Treatment of LPP and FFACompletedNCT065127661 country
- Baricitinib (LY3009104) in the Treatment of Cutaneous Lichen PlanusCompletedNCT05188521Phase 21 country
- Ixekizumab in Adult Patients With Lichen Planus and Lichen PlanopilarisCompletedNCT05030415Early Phase 11 country
- Role of Neurogenic Inflammation and Topical 6% Gabapentin Therapy in Symptomatic Scarring AlopeciaCompletedNCT03346668Early Phase 11 country
- Dipeptidyl Peptidase-4 Link With Oral Cancer and Premalignant LesionsCompletedNCT060870421 country
- Analysis of Impact of KeryFlex on Quality of Life for Retronychia or Lichen Planus Adult PatientsCompletedNCT05699499Not applicable1 country
- PoC Study to Evaluate the Efficacy and Safety of Secukinumab 300 mg in Patients With Lichen PlanusCompletedNCT04300296Phase 23 countries
- Early Detection of Vulval CAncer Through Self-Examination (EDuCATE): Intervention StudyCompletedNCT04952961Not applicable1 country
- Adjunctive Oral Systemic Vitamin E Therapy on Salivary Nitric Oxide Level in Patients With Erosive Oral Lichen PlanusCompletedNCT05787925Not applicable1 country
- Efficacy of Intralesional Injection of Platelet Rich Plasma in the Treatment of Patients With Erosive Oral Lichen PlanusCompletedNCT03293368Phase 21 country
- Fractional CO2 Laser for the Treatment of Lichen Planus PigmentosusWithdrawnNCT05170308Not applicable1 country
- a Flexible Wound Dressing for the Management of Genital Skin ConditionsCompletedNCT05396261Not applicable1 country
- Design and Validation of a New Assessment Tool for Lichen PlanopilarisStatus unknownNCT030825601 country
- Oral Low-Dose Naltrexone for Lichen Planopilaris and Frontal Fibrosing AlopeciaCompletedNCT04409041Phase 21 country
- Propolis Extract, Nanovitamin C and Nanovitamin E on Desquamative GingivitisStatus unknownNCT05124366Not applicable1 country
- Methods Validation Assessment for Study of Inflammatory Skin DiseaseCompletedNCT037968061 country
- Topical Ruxolitinib Lichen PlanusCompletedNCT03697460Phase 21 country
- Dexamethasone Solution for the Treatment of Oral Lichen PlanusCompletedNCT02850601Phase 21 country
- Assessment of PD-1 and PD-L1Tissue Expression Levels in Lichen Planus Patients: A Case-Control StudyStatus unknownNCT048923811 country