An observational study in Lichen Planus, sponsored by Istanbul Training and Research Hospital. Completed at 1 site in Turkey (Türkiye). Open to participants aged 18 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-05-06.
Sponsored by Istanbul Training and Research Hospital · Observational
This study investigates smell and taste function in patients diagnosed with lichen planus, a chronic inflammatory condition affecting the skin and mucous membranes.
Adults aged 18-65 with lichen planus participated in taste and smell tests. Oral and nasal examinations were performed to check for mucosal involvement, and nasal endoscopy was used to further evaluate nasal involvement.
A healthy control group of similar age also underwent taste and smell tests to compare results with the lichen planus patients.
The study aims to better understand how lichen planus affects smell and taste, which may help improve patient care. Participation is voluntary, and all information collected will be kept confidential.
The study aims to evaluate the impact of lichen planus on olfactory and gustatory functions in adults aged 18-65. Participants with lichen planus underwent taste and smell testing, oral and nasal mucosal examinations, and nasal endoscopy to detect potential mucosal involvement. A matched healthy control group also completed taste and smell tests to provide comparative data. This design allows the assessment of whether mucosal involvement in lichen planus correlates with changes in taste and smell, which may contribute to better clinical understanding and management of the disease.
74 studies on the registry are indexed under Lichen Planus; 15 are open to participants now.
This study's enrollment of 88 is close to the median of 80 across 17 observational studies indexed under Lichen Planus.
Browse Lichen Planus studies →Istanbul Training and Research Hospital is the lead sponsor of 66 studies on the registry; 15 are open to participants now.
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The study includes adults aged 18-65 years with a clinical diagnosis of lichen planus, as well as healthy volunteers without lichen planus. Participants were assessed for smell and taste function, and the patient group also underwent oral and nasal mucosal examinations, including nasal endoscopy. Both male and female participants were included.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Age 18-65 years Clinically diagnosed with lichen planus (patient group) Healthy individuals without lichen planus (control group) Willing and able to provide
Exclusion Criteria:
Nasal septum deviation Nasal polyposis, congenital olfactory dysfunction, chronic rhinosinusitis, or allergic rhinitis History of head trauma History of nasal or paranasal surgery Psychiatric or neurological disorders (e.g., Parkinson's disease, Alzheimer's disease) Persistent loss of smell following COVID-19 infection Pregnancy or breastfeeding
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Participants undergo taste and smell testing, oral and nasal examinations, and nasal endoscopy to assess mucosal involvement.
Other: Grup 1 - Lichen Planus Patients Intervention Name: Taste and Smell Testing, Oral and Nasal Examination, Nasal Endoscopy Intervention Description: Participants undergo taste and smell testing to assess
Participants undergo taste and smell testing to provide comparative data with the lichen planus group.
Other: Grup 1 - Lichen Planus Patients Intervention Name: Taste and Smell Testing, Oral and Nasal Examination, Nasal Endoscopy Intervention Description: Participants undergo taste and smell testing to assess
Group 1 - Lichen Planus Patients: Participants undergo taste and smell testing to assess sensory function, oral and nasal examinations to evaluate mucosal involvement, and nasal endoscopy for detailed nasal assessment. Group 2 - Healthy Controls: Participants undergo taste and smell testing to provide comparative data for the lichen planus group.
Smell and Taste Function
Participants underwent standardized smell (olfactory) and taste (gustatory) tests to assess sensory function. Tests were performed on both lichen planus patients and healthy controls to compare results and evaluate the impact of mucosal involvement on smell and taste function. Time Frame: Single visit assessment
Time frame: Day 1
Smell and taste function in patients with lichen planus
Participants underwent standardized smell (olfactory) and taste (gustatory) tests to assess sensory function. Tests were performed on both lichen planus patients and healthy controls to compare results and evaluate the impact of mucosal involvement on smell and taste function.
Time frame: Day 1
Plan to share: No — Individual participant data (IPD) will not be shared due to privacy and confidentiality considerations for study participants.
No publications or documents are linked to this record.
Ran from Jan 2026 to primary completion in Mar 2026, 2 months.
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This study is completed, as verified in Apr 2026. You cannot join it, but the record below documents what was studied.
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Istanbul Training and Research Hospital