Lichen Planus, Oral clinical trials
The registry lists 142 studies for Lichen Planus, Oral across more than 10 countries. 27 are recruiting or about to start. 130 of them are mainly about Lichen Planus, Oral (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.
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Who runs them
Cairo University (18) · Ain Shams University (10) · Catholic University of the Sacred Heart (4) · University of Zagreb (3) · Mashhad University of Medical Sciences (3) · Wroclaw Medical University (3) · Fayoum University (3) · University of Catania (3)
What is being tested here
Drugs under test in Lichen Planus, Oral studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Clobetasol | 1 | 1 | 4 |
| Triamcinolone Acetonide | 1 | 2 | 4 |
| Triamcinolone | 1 | 2 | 4 |
| Aminolevulinic Acid | 1 | 0 | 2 |
| Hyaluronic Acid | 1 | 0 | 1 |
| Bromelains | 1 | 0 | 1 |
| Topical Corticosteroid | 1 | 0 | 1 |
| Tofacitinib | 1 | 0 | 1 |
| Resveratrol | 1 | 0 | 1 |
| Dexamethasone | 0 | 0 | 4 |
Drug classes tested here Corticosteroids 2 open · Calcineurin inhibitors 7
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026Evaluation of Artificial Intelligence in Diagnosis and Risk Assessment of Oral Potentially Malignant Disorders · Ain Shams University
- Nov 2026Hypnotherapy for Oral Lichen Planus. Patients with Clinically and Histologically Confirmed Oral Lichen Planus Would Be Randomized for Hypnotherapy Vs Psychoeducation About the Pyschoneuroimmune System. Follow Up Would Be Done At 2, 6, 12 Weeks After. · Tel-Aviv Sourasky Medical Center
- Dec 2026Effectiveness of a Sodium Hyaluronate 0.01% and Sh-Oligopeptide-85 SP Mouthwash for the Treatment of Symptomatic Oral Lichen Planus · Universidad Complutense de Madrid
- Dec 2026Salivary IL-8 and Serum IL-6 as Biomarkers for Oral Potentially Malignant Disorders in Smokers and Never-Smokers · British University In Egypt
- Jan 2027Evaluation of Efficacy and Safety of add-on Tofacitinib in Patients With Oral Lichen Planus · All India Institute of Medical Sciences, Bhubaneswar
- Apr 2027SYsteMatical Trained learnIng aLgorithms for Oral carcInogenesiS Interpretation by Optical Coherence Tomography · University of Palermo
- Apr 2027Low Level Laser Therapy With Injectable Platelet Rich Fibrin in Management of Oral Lichen Planus · Ain Shams University
- Apr 2027Observational Study of OROSEDAL in Sore Throat and Minor Oral Lesions · Laboratoires Elerte
- May 2027Curcumin-mediated Photodynamic Therapy Versus Photobiomodulation in the Treatment of Oral Erosive Lichen Planus · Alexandria University
- Oct 2027Mucoadhesive Modified-Release Formulations for the Topical Treatment of Symptomatic Oral Lichen Planus · University of Palermo
Who these studies take
Of the 14 Lichen Planus, Oral studies recruiting now, 10 (71%) set no upper age limit and 2 (14%) stop at 75 or younger. 3 (21%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 3 (21%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (21%) | 3 (21%) |
| 18 | 12 (86%) | 12 (86%) |
| 30 | 14 (100%) | 14 (100%) |
| 40 | 14 (100%) | 14 (100%) |
| 50 | 14 (100%) | 14 (100%) |
| 65 | 14 (100%) | 14 (100%) |
| 75 | 13 (93%) | 13 (93%) |
| 85 | 11 (79%) | 11 (79%) |
Across all 142 studies, recruiting or not: 37% stop at 75 or younger and 18% at 65; 16% take children; 1% are for women only and 0% for men only; 30% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Lichen Planus, Oral studies take
Of 20 interventional studies with no phase under Lichen Planus, Oral, half reached primary completion within 14 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 14 mo9–27 · 20 studies | — | — |
| Observational | 7 mo3–13 · 15 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 14, 2026.
Newly registered3
- Effects Of Topical Clobetasol Versus Coconut Oil Cream In The Treatment Of Oral Lichen PlanusNov 9, 2026NCT07924865
- Salivary IL-8 and Serum IL-6 as Biomarkers for Oral Potentially Malignant Disorders in Smokers and Never-SmokersNov 4, 2026NCT07915570
- Curcumin-mediated Photodynamic Therapy Versus Photobiomodulation in the Treatment of Oral Erosive Lichen PlanusNov 2, 2026NCT07910175
Studies
Recruiting first, then most recently updated. Showing 50 of 142. Browse all 142 → or search them.
- Salivary IL-8 and Serum IL-6 as Biomarkers for Oral Potentially Malignant Disorders in Smokers and Never-SmokersRecruitingNCT079155701 country
- Curcumin-mediated Photodynamic Therapy Versus Photobiomodulation in the Treatment of Oral Erosive Lichen PlanusNot yet recruitingNCT07910175Not applicable1 country
- Improving Prescribing Quality for Oral Mucosal Disorders Using a Pharmacist-Led ModelNot yet recruitingNCT07721090Not applicable
- Effect of Topical Bromelain Versus Topical Corticosteroids in the Management of Oral Lichen PlanusRecruitingNCT06981767Phase 21 country
- Observational Study of OROSEDAL in Sore Throat and Minor Oral LesionsRecruitingNCT076203531 country
- Periodontal Status in Patients With Oral Lichen PlanusNot yet recruitingNCT07597616
- Rate of Malignant Transformation and Clinical Characteristics Among an Oral Lichen Planus Cohort: a Retrospective Center ExperienceRecruitingNCT069348631 country
- Photobiomodulation, Photodynamic Therapy, and Clobetasol in the Treatment of Oral Lichen Planus.RecruitingNCT07278999Not applicable1 country
- Low-cost Screening and Image-guided Photodynamic Therapy (PDT) of Premalignant and Malignant Oral LesionsNot yet recruitingNCT06876038Phase 21 country
- The Therapeutic Effect of Curcumin in Nanogels Compared to 0.1% FAO in the Management of Oral Lichen PlanusRecruitingNCT06932848Not applicable1 country
- Role of Subgingival Instrumentation in Oral Lichen PlanusNot yet recruitingNCT07381595Not applicable1 country
- Effectiveness of a Sodium Hyaluronate 0.01% and Sh-Oligopeptide-85 SP Mouthwash for the Treatment of Symptomatic Oral Lichen PlanusNot yet recruitingNCT07280442Phase 41 country
- Cardiovascular and Prothrombotic Risk in Patients With Oral Lichen Planus.Not yet recruitingNCT07151014
- Evaluation of Artificial Intelligence in Diagnosis and Risk Assessment of Oral Potentially Malignant DisordersNot yet recruitingNCT07318922
- Evaluation of Efficacy and Safety of add-on Tofacitinib in Patients With Oral Lichen PlanusRecruitingNCT07131813Phase 41 country
- Mucoadhesive Modified-Release Formulations for the Topical Treatment of Symptomatic Oral Lichen PlanusRecruitingNCT07100613Phase 21 country
- SYsteMatical Trained learnIng aLgorithms for Oral carcInogenesiS Interpretation by Optical Coherence TomographyRecruitingNCT063210031 country
- Thyme Honey for Management of Oral Lichen PlanusEnrolling by invitationNCT06810752Phase 1/21 country
- Hypnotherapy for Oral Lichen Planus. Patients with Clinically and Histologically Confirmed Oral Lichen Planus Would Be Randomized for Hypnotherapy Vs Psychoeducation About the Pyschoneuroimmune System. Follow Up Would Be Done At 2, 6, 12 Weeks After.Enrolling by invitationNCT06697574Not applicable1 country
- Evaluation of Desmoglein-3 Autoantibodies in the Tissues of Oral Lichen Planus and Correlation with Disease SeverityNot yet recruitingNCT06652477
- Evaluation of the Efficacy of 0.08% Tacrolimus Nanoencapsulated Aqueous Solution Spray Vs. 0.1% Free Tacrolimus Commercial Ointment in the Treatment of Oral Lichen PlanusRecruitingNCT06591884Phase 1/21 country
- Periodontal Initial Treatment Combined With Glucocorticoid Therapy for Erosive Oral Lichen PlanusNot yet recruitingNCT06498180Not applicable1 country
- Efficacy of Probiotic Capsules With Topical Clobetasol Propionate in OLP TreatmentRecruitingNCT06119672Phase 31 country
- Oral Cancer Screening for Early Detection of Premalignant Disorders (PMOD)RecruitingNCT05296941Not applicable1 country
- Treatment of Oral Lichen Planus With Paeoniflorin and Photodynamic TherapyRecruitingNCT05973097Not applicable1 country
- Efficacy of Ginger Muco-bioadhesive Gel in Management of Oral Lichen Planus With Immunohistochemical AnalysisNot yet recruitingNCT05882864Phase 4
- Prediction of Malignant Transformation of Oral Leukoplakia Using a MAGE-A-based ImmunoscoreRecruitingNCT039753221 country
- Effects Of Topical Clobetasol Versus Coconut Oil Cream In The Treatment Of Oral Lichen PlanusActive, not recruitingNCT07924865Not applicable1 country
- Efficacy and Safety of Baricitinib in Oral Lichen Planus: a Proof-of-Concept StudyCompletedNCT06158113Phase 21 country
- Efficacy of Coconut Gel Compared to Corticosteroid Gel in the Management of Oral Lichen PlanusCompletedNCT07100145Phase 41 country
- Low Level Laser Therapy With Injectable Platelet Rich Fibrin in Management of Oral Lichen PlanusActive, not recruitingNCT07846891Phase 41 country
- Identification of Oral Lesions Through an Autofluorescence SystemCompletedNCT05942794Not applicable1 country
- Efficacy of Aloe Vera Compared to Corticosteroid in Topical Treatment of Oral Lichen Planus and on Salivary Levels of Tumor Necrosis Factor AlphaCompletedNCT07792512Phase 41 country
- Treatment Outcomes and Patient Satisfaction of Oral Lichen Planus TreatmentCompletedNCT06988527Phase 21 country
- Impact of Topical Clobetasol on Gingival Crevicular Fluid miRNAs in Subjects Affected by Oral Lichen PlanusCompletedNCT05818618Not applicable1 country
- Impact of PDT and Topical Corticosteroids on Taste Perception and Salivary Oxidative Stress Markers in Patients With OLPCompletedNCT07536737Not applicable1 country
- Clinical and Molecular Correlates of Response to First Line Treatment in Lichen PlanusActive, not recruitingNCT053305721 country
- Dual-light Antibacterial Photodynamic Therapy as an Adjunctive Treatment to Corticosteroid Treatment in OLPCompletedNCT05401201Not applicable1 country
- Study of Inflammatory Role of Epstein-Barr Virus (EBV) in Atrophic and Erosive Forms of Oral Lichen PlanusCompletedNCT02276573Not applicable1 country
- Unveiling the Protein Expression Patterns in Oral Lichen Planus and Leukoplakia Through Comparative Salivary ProteomicsCompletedNCT074163181 country
- Discomfort Following Oral Biopsy Comparing Laser and Punch BiopsyCompletedNCT07414797Not applicable1 country
- The Efficacy of Selenium as an Alternative or Complementary Topical Treatment of Oral Lichen PlanusCompletedNCT06362005Phase 41 country
- Efficacy and Safety of add-on Apremilast Versus add-on Methotrexate in Patients With Oral Lichen PlanusCompletedNCT06260904Phase 41 country
- Relationship Between Oral Lichen Planus and Autoimmune Thyroid DiseasesCompletedNCT054032161 country
- Evaluation of Efficacy of Neem (Azadirachta Indica) Versus Triamcinolone Acetonide in the Treatment of Oral Lichen Planus.CompletedNCT07141446Phase 1/21 country
- Metagenomic Analysis of the Oral Microbiome in Patients With Oral Lichen Planus: A Pilot Study in the Turkish PopulationCompletedNCT071371561 country
- Efficacy of Topical Glucosamine Versus Corticosteroid in Oral Lichen PlanusCompletedNCT07114016Phase 41 country
- Artificial Intelligence Based Program to Classify Oral Cavity Findings Based on Clinical Image AnalysisCompletedNCT063255141 country
- Evaluating LP-10 in Subjects With OLPActive, not recruitingNCT06233591Phase 21 country
- Systemic Absorption of Dexamethasone Oral Rinse in Patients With Oral Lichen PlanusWithdrawnNCT06428630Early Phase 11 country