Hypoventilation clinical trials
The registry lists 96 studies for Hypoventilation across more than 10 countries. 21 are recruiting or about to start. 44 of them are mainly about Hypoventilation (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its narrower condition Obesity Hypoventilation Syndrome too: 165 studies, 31 open.
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· Enrollment: 300 → 450 participants
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Who runs them
Beth Israel Deaconess Medical Center (3) · Istanbul University (3) · Universidad Complutense de Madrid (2) · Stanford University (2) · National University Health System, Singapore (2) · University Medical Center Groningen (2) · University Hospital, Grenoble (2) · Oregon Health and Science University (2)
What is being tested here
Drugs under test in Hypoventilation studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 8
- Dec 2026Effects of Controlled Breathing on Cardiorespiratory Variables in Multiple Myeloma · Universidad Complutense de Madrid
- Dec 2026Smartphone Camera Measurement of Breathing-Related Heart Rate Variability Compared With ECG in Healthy Adults · BELL Therapeutics Inc.
- Dec 2026Assessing the Acute Effects of Virtual Reality Interventions on Stress · Prof. Dominique de Quervain, MD
- Dec 2026Investigating Health Related Quality of Life in Patients With Chronic Respiratory Failure · Guy's and St Thomas' NHS Foundation Trust
- Jan 2027Effects of Controlled Breathing Added to Therapeutic Exercise in Multiple Myeloma · Universidad Complutense de Madrid
- Jan 2027Virtual Reality Relaxation for Insomnia · Laval University
- Apr 2027Pupillometry in Identifying Risk of Postoperative Opioid-induced Respiratory Depression in Children Undergoing Tonsillectomy · NeurOptics Inc
- Jun 2027PREdicting Failure of Non-inVasIve Ventilatory Support Using Non-invaSIve mONitoring in Non-intubated Patients With Acute Hypoxemic Respiratory Failure or Post-extubation Failure. The PREVISION Study · Unity Health Toronto
Who these studies take
Of the 14 Hypoventilation studies recruiting now, 8 (57%) set no upper age limit and 5 (36%) stop at 75 or younger. 2 (14%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 5 (36%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (14%) | 2 (14%) |
| 18 | 12 (86%) | 12 (86%) |
| 30 | 13 (93%) | 13 (93%) |
| 40 | 11 (79%) | 11 (79%) |
| 50 | 11 (79%) | 11 (79%) |
| 65 | 10 (71%) | 10 (71%) |
| 75 | 9 (64%) | 9 (64%) |
| 85 | 9 (64%) | 9 (64%) |
Across all 96 studies, recruiting or not: 36% stop at 75 or younger and 31% at 65; 13% take children; 5% are for women only and 3% for men only; 20% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Hypoventilation studies take
Of 35 interventional studies with no phase under Hypoventilation, half reached primary completion within 15 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 15 mo5–26 · 35 studies | — | 15 mo5–26 · 35 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 50 of 96. Browse all 96 → or search them.
- Smartphone Camera Measurement of Breathing-Related Heart Rate Variability Compared With ECG in Healthy AdultsNot yet recruitingNCT07922161Not applicable1 country
- Assessing the Acute Effects of Virtual Reality Interventions on StressRecruitingNCT07191288Not applicable1 country
- Effects of Controlled Breathing Added to Therapeutic Exercise in Multiple MyelomaRecruitingNCT07312942Not applicable1 country
- Effects of Controlled Breathing on Cardiorespiratory Variables in Multiple MyelomaRecruitingNCT07376733Not applicable1 country
- International Rapid-onset Obesity With Hypothalamic Dysfunction, Hypoventilation & Autonomic Dysregulation (ROHHAD) RegistryRecruitingNCT031357301 country
- Virtual Reality Relaxation for InsomniaRecruitingNCT07630532Not applicable1 country
- Investigating Health Related Quality of Life in Patients With Chronic Respiratory FailureRecruitingNCT042367261 country
- Pupillometry in Identifying Risk of Postoperative Opioid-induced Respiratory Depression in Children Undergoing TonsillectomyRecruitingNCT075731501 country
- Slow Breathing and Resistance Exercise in FibromyalgiaEnrolling by invitationNCT07404384Not applicable1 country
- The Effect of phoSPHocreatine on mEdical Emergency Team (Met) tREated PatientsRecruitingNCT06503016Phase 31 country
- To Assess the Types of Mechanical Ventilation in Enabling Therapeutic Bronchofiberoscopy in Patients With Decompensated Respiratory Acidosis (Complete Respiratory Failure).Not yet recruitingNCT06970041Not applicable
- Postoperative Respiratory and Activity MonitoringRecruitingNCT062398311 country
- "Lung Barometric Measurements in Normal And in Respiratory Distressed Lungs"RecruitingNCT044847271 country
- Overview: Use of Respiratory Support At Home in ChildrenNot yet recruitingNCT066926601 country
- Effects of End-inspiratory Pause on VentilationNot yet recruitingNCT06692634Not applicable1 country
- Non-invasive Monitoring of Mixed Venous Oxygen Saturation Using the Capnodynamic Method in AdultsNot yet recruitingNCT06632197
- Investigating the Effect of Yoga-based Breathing Styles on the Human Brain, With a Focus on MemoryRecruitingNCT05846425Not applicable1 country
- Influence of Hypoxic, Normobaric and Hypobaric Training on the Immunometabolism of Post-covid-19 AthletesRecruitingNCT06128941Not applicable1 country
- Customized Masks in Non-Invasive Mechanical VentilationRecruitingNCT06215391Not applicable1 country
- The Effect of Slow Breathing Exercise Applied to Patients on Pulse, Blood Pressure and Quality of LifeRecruitingNCT06098222Not applicable1 country
- Opioid-sparing Versus Sevoflurane Anesthesia on Early Postoperative Hypoventilation in Laparoscopic Bariatric SurgeryNot yet recruitingNCT05962671Phase 41 country
- PREdicting Failure of Non-inVasIve Ventilatory Support Using Non-invaSIve mONitoring in Non-intubated Patients With Acute Hypoxemic Respiratory Failure or Post-extubation Failure. The PREVISION StudyActive, not recruitingNCT067164631 country
- "Living Low - Training High" Methods and Physiological Responses in Well-trained SwimmersCompletedNCT06253039Not applicable1 country
- Structural Modification In Supraglottic Airway DeviceCompletedNCT04498598Not applicable1 country
- Post-Extubation High-Flow Nasal Cannula Versus Non-Invasive Ventilation in Type II Respiratory FailureCompletedNCT06918288Not applicable1 country
- Vital Signs-Integrated Patient-Assisted Intravenous Opioid Analgesia for Post Surgical PainActive, not recruitingNCT04011163Phase 2/31 country
- Feasibility of the Comfort Measures Only Time Out (CMOT)Active, not recruitingNCT05861323Not applicable1 country
- Slow Yogic-Derived Breathing and Respiration and Cardiovascular Variability in Spinal Cord Injury PatientsCompletedNCT05480618Not applicable1 country
- Risk Indicators and IPI Performance in Sedation-Related Respiratory Deterioration in COPDCompletedNCT072629051 country
- Non-Invasive Monitoring of Respiratory Function in Spontaneously Breathing Patients With COVID-19 InfectionTerminatedNCT043564431 country
- Influence of Yogic Breathwork on CSF CirculationCompletedNCT03858309Not applicable1 country
- The Effect of Obesity Hypoventilation Syndrome on Exercise Capacity, Peripheral Muscle Strength, and Quality of Life in Obese IndividualsCompletedNCT061425131 country
- Effects of Exercise Training on Exercise Capacity and Sleep Quality in Patients With Obesity Hypoventilation SyndromeCompletedNCT05398068Not applicable1 country
- Amount of Droplet Formed During Percutaneous Dilatational TracheostomyCompletedNCT05813977Not applicable1 country
- The IPAd Study: Exploring the Association Between Insomnia and Positive Airway Pressure Adherence in ChildrenCompletedNCT059491641 country
- THRIVE Use in Pediatric Populations- Multi SiteCompletedNCT04322994Not applicable1 country
- Influence of Yogic Breathwork on SleepCompletedNCT05756686Not applicable1 country
- How Differences in Oximeter Performance May Affect Clinical DecisionCompletedNCT044745741 country
- Transcutaneous CO2 Measurement - From Hospital to HomeCompletedNCT066948701 country
- Study of the Effects of Transcutaneous Auricular Vagus Nerve Stimulation Combined with Slow Breathing on InsomniaCompletedNCT06614803Not applicable1 country
- The Effect of Sarcopenic Obesity on Sleep in Individuals With Obesity Hypoventilation SyndromeStatus unknownNCT061365331 country
- Concomitant Bedside Percutaneous Tracheostomy and Ultrasound GastrostomyWithdrawnNCT05955534Not applicable1 country
- Breathing Interventions for Relaxation: Dosing Through Extended ExhaleCompletedNCT02870868Not applicable1 country
- Spirometric Detection of Esophageal IntubationWithdrawnNCT02052869Not applicable1 country
- Non-invasive Ventilator Modems: a Qualitative StudyCompletedNCT03905382Not applicable1 country
- Health Outcomes With CPAP or NIV in Patients With COPD and a Sleep Related Breathing DisorderTerminatedNCT056237091 country
- Neo RQI: The Effect of Neonatal Resuscitation Quality Improvement Cart Booster Training Skills RetentionCompletedNCT05147922Not applicable1 country
- Postoperative Opioid and Respiratory Depression in Opioid Naive and Chronic Opioid PatientsCompletedNCT062272081 country
- Clinical Features of COVID-19 PatientsCompletedNCT048153041 country
- Tele-monitoring of Patients With Home Mechanical Ventilation (HMV) Trough Telemedicine System (MyVENT)CompletedNCT03971630Not applicable1 country