An observational study in Chronic Obstructive Pulmonary Disease, Respiratory Failure and Neuromuscular Diseases, sponsored by Guy's and St Thomas' NHS Foundation Trust. Recruiting at 1 site in United Kingdom. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-06-04.
Sponsored by Guy's and St Thomas' NHS Foundation Trust · Observational
To determine the quality of life of patients living with chronic respiratory failure and the impact interventions have on it.
To determine the quality of life of patients living with chronic respiratory failure and the impact interventions have on it.
5,520 studies on the registry are indexed under Pulmonary Disease, Chronic Obstructive; 856 are open to participants now.
This study's planned enrollment of 200 is above the median of 158 across 1,497 observational studies indexed under Pulmonary Disease, Chronic Obstructive.
Browse Pulmonary Disease, Chronic Obstructive studies →Guy's and St Thomas' NHS Foundation Trust is the lead sponsor of 295 studies on the registry; 80 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Patients with chronic respiratory failure being treated with a form of ventilation of mechanical insufflation-exsufflation therapy.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Diagnosed with chronic respiratory failure receiving any of:
Exclusion Criteria:
Users of non-invasive ventilation
Other: Questionnaire
Long term tracheostomy ventilated patients
HRQoL questionnaires
HRQoL score
Outcome of various HRQoL assessment tools.
Time frame: Day 0: At the first outpatient clinical consultation with the clinical team
Change in HRQoL score
Change in HRQoL assessment tool score at next clinical follow-up.
Time frame: 6 months following first assessment for Outcome 1
Plan to share: No
No publications or documents are linked to this record.
Started Dec 2019 (actual). Primary completion is estimated for Dec 2026, 84 months after the start.
How these figures are worked out, and which studies are left out of them.
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
Contact study teamGet an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Pulmonary Disease, Chronic Obstructive →
Guy's and St Thomas' NHS Foundation Trust →