Hyperparathyroidism, Primary clinical trials
The registry lists 99 studies for Hyperparathyroidism, Primary across more than 10 countries. 23 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-23.
Status
- Completed
- 56
- Recruiting
- 15
- Status unknown
- 9
- Not yet recruiting
- 7
- Withdrawn
- 5
- Terminated
- 4
Phase
- Phase 2
- 12
- Phase 3
- 11
- Phase 4
- 10
- Phase 1
- 5
Where
- United States
- 29
- Denmark
- 9
- France
- 9
- Sweden
- 6
- Italy
- 5
- Canada
- 3
Who runs them
Columbia University (6) · Amgen (6) · The Cleveland Clinic (3) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (3) · University of Pennsylvania (3) · M.D. Anderson Cancer Center (3) · Karolinska University Hospital (3) · Aristotle University Of Thessaloniki (3)
Studies
Recruiting first, then most recently updated. Showing 50 of 99 — search for more.
- Natural History Study of Parathyroid DisordersRecruitingNCT049699261 country
- Evaluation of the Role of Luteinizing Hormone (LH) and Human Chorionic Gonadotropin (hCG) in Adult Patients Undergoing Assessment for Endocrine DisordersRecruitingNCT078241021 country
- NIRAF-camera Versus Conventional Surgery in Preoperative Imaging Negative Primary HyperparathyroidismRecruitingNCT07812649Not applicable1 country
- Amino Acid Transporter System PET/CT Imaging in AATS-Related DiseasesRecruitingNCT073794631 country
- Patient Navigation to Improve Surgical Access in Primary HyperparathyroidismRecruitingNCT06562881Not applicable1 country
- Shortwave Infrared Surgical Imaging Device StudyEnrolling by invitationNCT077444251 country
- Accuracy of 18F-Fluorocholine PET/MR and NeuroEXPLORER PET/CT Imaging for Localization of Parathyroid TumorsRecruitingNCT07444723Phase 2/31 country
- Molecular and Immunohistochemical Profiling of Tumors in Patients With Parathyroid TumorsRecruitingNCT030394391 country
- Parathyroid Tumor Clonal StatusRecruitingNCT059978101 country
- Parathyroid Assessment of Symptoms French VersionRecruitingNCT064504311 country
- Aldosterone Variations in Patients With Primary Hyperparathyroidism After SurgeryNot yet recruitingNCT073889141 country
- Cohort Primary HyperparathyroidismRecruitingNCT054690871 country
- 18F-choline Positron-emission-tomography - Computed-tomography Compared to Conventional Imaging for Localizing Diseased Parathyroid Glands in Primary HyperparathyroidismRecruitingNCT07138820Not applicable1 country
- Parathyroid Adenoma Detection With Rubidium-82 ImagingNot yet recruitingNCT070994041 country
- WHITE CAP: Intra-operative Parathyroid Tissue Sensor (PTS)-Guided Assessment of Parathyroid Viability and Surgical Decision-MakingNot yet recruitingNCT07043010Not applicable1 country
- Bisphosphonate Prior to Parathyroidectomy in Primary HyperparathyroidismRecruitingNCT06859580Phase 41 country
- Is Intraoperative PTH Monitoring Obsolete in Times of Choline PET/CT? a Prospective Multicenter Cohort Study to Determine Whether the Regular Preoperative Use of Choline-PET/CT Scan Obviate the Need for Intraoperative PTH-measurement in Patients with Primary HyperparathyreoidismNot yet recruitingNCT068046811 country
- Autofluorescence in Surgery for Primary HyperparathyroidismRecruitingNCT06230380Not applicable1 country
- Thermal Ablation Versus Parathyroidectomy for Primary HyperparathyroidismNot yet recruitingNCT06708871
- Diagnostic Performance of [11C]Choline PET/CT In the Preoperative Assessment of Primary HyperparathyroidismNot yet recruitingNCT066479661 country
- Calcitonin Pre-treatment to Improve SPECT-CT SensitivityRecruitingNCT03935984Phase 41 country
- Genetic Bases of Neuroendocrine Neoplasms in Mexican PatientsRecruitingNCT065235821 country
- The Bone-parathyroid Crosstalk in Primary HyperparathyroidismNot yet recruitingNCT055564991 country
- Evaluation of the Role of Intraoperative Neuromonitoring(IONM) in Patients Undergoing Parathyroid Surgery for Solitary Parathyroid AdenomaCompletedNCT07836335Not applicable1 country
- Glycemic Control, Type II Diabetes, ParathyroidectomyActive, not recruitingNCT057617431 country
- 18F-Fluorocholine Positron Emission Tomography (PET) for the Detection of Parathyroid AdenomasCompletedNCT04895631Phase 31 country
- Evaluation of a Cincalcet Suppression TestCompletedNCT01103206Phase 41 country
- Primary Hyperparathyroidism and Gut MicrobiotaTerminatedNCT049486711 country
- Surgery for Primary Hyperparathyroidism (pHPT) in Patients Older Than 65 Years Compared With Follow-upCompletedNCT01087619Not applicable1 country
- Upfront Ultrasound for Preoperative Localization in Primary HyperparathyroidismCompletedNCT070688671 country
- Near Infrared Autofluorescence (NIRAF) Detection for Identifying Parathyroid Glands During ParathyroidectomyCompletedNCT05152927Not applicable1 country
- Evaluating Impact of Near Infrared Autofluorescence (NIRAF) Detection for Identifying Parathyroid Glands During ParathyroidectomyCompletedNCT05022641Not applicable1 country
- Intraoperative Identification of Parathyroid Adenomas Using PTeye™ and FLUOBEAM® LX: a Prospective Cohort StudyActive, not recruitingNCT067882231 country
- Near Infrared Autofluorescence Imaging in Minimally-Invasive Video-Assisted Parathyroidectomy (NIRAF MIVAP Study)CompletedNCT067797601 country
- Primary Hyperparathyroidism: Short-term Calcimimetics Treatment - Relevance for Parathyroid Surgery Decisions?CompletedNCT02227264Not applicable1 country
- Object Assessment of Improvement in Non-Specific Symptoms After Parathyroidectomy for Primary HyperparathyroidismCompletedNCT063378251 country
- Circulating miRNA in Primary HyperparathyroidismCompletedNCT039311091 country
- Evaluating Impact of NIRAF Detection for Identifying Parathyroid Glands During ParathyroidectomyCompletedNCT04299425Not applicable1 country
- Cohort Trial on Perioperative Localization Techniques of Parathyroid AdenomasTerminatedNCT04013100
- FCH PET/MRI Parathyroid LocalizationCompletedNCT03324893Not applicable1 country
- Trial Comparing 2 Diagnostic Strategies for Preoperative Localization of Parathyroid Adenoma in Primary Hyperparathyroidism:TEMP / CT With Tc99m-sestaMIBI or PET / CT With F18-choline in First IntentionCompletedNCT04040946Phase 31 country
- Evaluating Alternative Medical Therapies in Primary HyperparathyroidismCompletedNCT02525796Phase 2/31 country
- The Crosstalk Between Calcium-sensing Receptor Signaling and Endocannabinoid System in Primary HyperparathyroidismCompletedNCT038316201 country
- Optimization and Individualization of Diagnostic Scintigraphy Protocol and Minimally Invasive Radio-guided Parathyroid SurgeryCompletedNCT04344886Not applicable1 country
- Impact of Parathyroidectomy on Renal FunctionStatus unknownNCT047980921 country
- Osteoporosis in Primary HyperparathyroidismStatus unknownNCT04085419Phase 41 country
- Denosumab in Primary HyperparathyroidismTerminatedNCT01558115Phase 41 country
- Vitamin D Metabolism in Patients With Endocrine DisordersCompletedNCT04844164Phase 11 country
- Effect of Mechanical Loading on vBMD and Geometry in Patients With Primary HyperparathyroidismCompletedNCT05426512
- Frequency of Hyperparathyroidism in Postmenopausal Osteoporosis and Its TreatmentCompletedNCT05347082Not applicable1 country