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CompletedNCT02854345PARAT-CZTUpdated Sep 19, 2024

Preliminary Study Concerning the Validity of Parathyroid Exploration on a CZT Camera

An interventional study of Tomoscintigraphic parathyroid imaging on a CZT camera in Primary Hyperparathyroidism, sponsored by Centre Hospitalier Universitaire de Besancon. Completed at 1 site in France. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2024-09-19.

Sponsored by Centre Hospitalier Universitaire de Besancon · Not applicable, Interventional, and Diagnostic

From the registry’s dates

  • Registered 1 year 10 months after the study started (first participant enrolled Sep 2014, registered Jul 2016).
Phase
Not applicable
Study type
Interventional
Enrollment
45
Allocation
Not applicable
Ages
18 Years to 80 Years
Sex
All
01

Study summary

The goal of this study is to assess the performance of parathyroid imaging on a cardiac-dedicated CZT camera, compared to planar pinhole imaging, in patients referred for primary hyperparathyroidism.

Read the detailed description

The goal is to determine if parathyroid tomoscintigraphy on a CZT camera can provide at least equivalent diagnostic performance, compared with planar pinhole imaging.

02

Conditions studied

  • Primary Hyperparathyroidism

Keywords

  • CZT camera
  • pinhole
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In context

Hyperparathyroidism, Primary

105 studies on the registry are indexed under Hyperparathyroidism, Primary; 23 are open to participants now.

This study's enrollment of 45 is below the median of 67 across 57 interventional studies indexed under Hyperparathyroidism, Primary.

Browse Hyperparathyroidism, Primary studies →

Lead sponsor

Centre Hospitalier Universitaire de Besancon is the lead sponsor of 449 studies on the registry; 98 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • suffering from sporadic primary hyperparathyroidism
  • referred to the Nuclear Medicine Dept for a pre-operative scintigraphy of the parathyroid glands
  • who have given their written consent
  • who benefit from the French Government Medical Insurance

Exclusion criteria

Exclusion Criteria:

  • pregnant women
  • ages \< 18 or > 80 years
  • hyperparathyroidism recidive after a first surgery
  • secondary or tertiary hyperparathyroidism
  • Multiple endocrine Neoplasia (MEN) type I context or familial history of hyperparathyroidism
  • absence of written consent
  • non-beneficiary of the French Government Medical Insurance
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Study design

Phase
Not applicable
Primary purpose
Diagnostic
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
45 participants (actual)

Study arms

  • Experimental
    Tomoscintigraphic parathyroid imaging on a CZT camera

    Tomoscintigraphic parathyroid imaging on a CZT camera

    Device: Tomoscintigraphic parathyroid imaging on a CZT camera

Interventions

  • DeviceTomoscintigraphic parathyroid imaging on a CZT camera
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What researchers measure

Primary outcomes

  1. Comparison of pathologic parathyroid detection performances between planar pinhole on Anger camera and tomoscintigraphy on CZT camera, gold standard being the pathological results after surgery

    Time frame: 6 months

07

Study locations

1 site
  • CHU Besancon
    Besançon, 25000, France
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References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 19, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT02854345
Responsible party
Sponsor
First posted
Aug 3, 2016
Start date
Sep 4, 2014
Primary completion
Sep 9, 2021
Completion
Sep 9, 2021
Last update
Sep 19, 2024

Study contacts

Constantin Ungureanu, MD
principal investigator · Centre Hospitalier Universitaire de Besancon

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Sep 2024. You cannot join it, but the record below documents what was studied.

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