An interventional study of [F-18]-FCH PET/MRI in 18F-fluorocholine, Positron-Emission Tomography and Hyperparathyroidism, Primary, sponsored by University Health Network, Toronto. Completed at 1 site in Canada. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2023-12-07.
Sponsored by University Health Network, Toronto · Not applicable, Interventional, and Diagnostic
A prospective trial comparing the accuracy of [F-18]-FCH PET/MRI to US and 99mTc-MIBI SPECT/CT for pre-operative parathyroid localization in patients with primary hyperparathyroidism
Exclusion Criteria:
Patients with primary hyperparathyroidism planned for parathyroidectomy
Diagnostic Test: [F-18]-FCH PET/MRI
Subjects will undergo the \[F-18\]-FCH PET/MRI within three months prior to scheduled parathyroidectomy.
Also known as: FCH PET/MRI, Fluorine-18 fluorocholine PET/MRI
Accuracy of [F-18]-FCH PET/MRI in localization of diseased parathyroid gland
Value of \[F-18\]-FCH PET/MRI next to Ultrasound of the Neck and 99mTc-MIBI SPECT/CT in determining which of the four parathyroid glands Reference standards: * Intra-operative location of the hyper functioning gland by inspection and post-operative pathological confirmation. * Determination of biochemical cure per usual standard of care: intraoperative PTH and calcium and PTH postoperatively.
Time frame: 1 month postoperatively
Plan to share: Undecided
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This study is completed, as verified in Dec 2023. You cannot join it, but the record below documents what was studied.
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University Health Network, Toronto