Hypercalciuria clinical trials
The registry lists 33 studies for Hypercalciuria across more than 10 countries. 4 are recruiting or about to start. 7 of them are mainly about Hypercalciuria (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-02.
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Who runs them
Calcilytix Therapeutics, Inc., a BridgeBio company (2) · University of Texas Southwestern Medical Center (2) · VA New York Harbor Healthcare System (2) · Professor Francine Ducharme (1) · Indiana University School of Medicine (1) · University of Utah (1) · University of Wisconsin, Madison (1) · Assiut University (1)
What is being tested here
Drugs under test in Hypercalciuria studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Rifampin | 1 | 0 | 2 |
| Phosphates | 1 | 0 | 1 |
| Indapamide | 1 | 0 | 1 |
| Citric Acid | 0 | 1 | 3 |
| Potassium Citrate | 0 | 1 | 3 |
| Vitamin D | 0 | 1 | 2 |
| Chlorthalidone | 0 | 0 | 2 |
| Encaleret | 0 | 1 | 1 |
| Fluconazole | 0 | 0 | 1 |
| Parathyroid Hormone | 0 | 1 | 1 |
Drug classes tested here Diuretics 1 open · Thiazide diuretics 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The study
- Oct 2027Diagnostic Work-up of Nephrocalcinosis in Children · Assiut University
Who these studies take
Of the 3 Hypercalciuria studies recruiting now, 2 (67%) set no upper age limit and 1 (33%) stop at 75 or younger. 2 (67%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (33%) | 1 (33%) |
| 18 | 3 (100%) | 3 (100%) |
| 30 | 3 (100%) | 3 (100%) |
| 40 | 3 (100%) | 3 (100%) |
| 50 | 3 (100%) | 3 (100%) |
| 65 | 3 (100%) | 3 (100%) |
| 75 | 2 (67%) | 2 (67%) |
| 85 | 2 (67%) | 2 (67%) |
Across all 33 studies, recruiting or not: 55% stop at 75 or younger and 45% at 65; 52% take children; 9% are for women only and 0% for men only; 12% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 11, 2026.
Newly registered1
- Diagnostic Work-up of Nephrocalcinosis in ChildrenOct 20, 2026NCT07882355
Studies
Recruiting first, then most recently updated. Showing 33 of 33. search them.
- Diagnostic Work-up of Nephrocalcinosis in ChildrenNot yet recruitingNCT07882355
- Rifampin in CYP24A1-related Hypercalcemia and HypercalciuriaRecruitingNCT03301038Phase 21 country
- The Impact of Phosphate Metabolism on Healthy AgingRecruitingNCT03771105Early Phase 11 country
- Treatment With Indapamide in Patients With Post-Surgical HypoparathyroidismRecruitingNCT07034677Phase 41 country
- Assessing the Impact of a Mode of Vitamin D Supplementation (Sequential Dose vs Daily Dose) on the Incidence of Hypercalciuria in Subjets Aged From 2 to 18 YearsCompletedNCT02975492Not applicable1 country
- Efficacy and Safety of Encaleret Compared to Standard of Care in Participants With ADH1Active, not recruitingNCT05680818Phase 310 countries
- ADH1 and ADH2 Disease Monitoring Study (DMS)Active, not recruitingNCT0522728713 countries
- Prevelance of Hypercalciuria in Children With Steroid Dependent Nephrotic SyndromeActive, not recruitingNCT071942131 country
- Vitamin D In the Prevention of Viral-induced Asthma in PreschoolersCompletedNCT03365687Phase 31 country
- Randall's Plaque Study: Pathogenesis and Relationship to NephrolithiasisActive, not recruitingNCT00169806Not applicable1 country
- Multicenter, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Fluconazole in Hypercalcicuric Patients With Increased 1.25(OH) 2D LevelsCompletedNCT04495608Phase 21 country
- HEXT (Hypo EXTended): Effect of PTH on Skeleton in HypoparathyroidismCompletedNCT01199614Phase 31 country
- Stone Disease in Children and Their FamiliesCompletedNCT00765531
- Treatment for Calcium Phosphate Kidney Stone DiseaseCompletedNCT01754779Phase 21 country
- Does Treatment of Hypovitaminosis D Increase Calcium Absorption?CompletedNCT00581828Phase 41 country
- Night Time Use of Thiazide Diuretics for Improved Reduction in Stone Risk in Stone Formers With Elevated Urine CalciumCompletedNCT02711670Not applicable1 country
- Bone Mineral Density and Vascular Calcifications in the Population of Lithiasis Patients With Idiopathic HypercalciuriaCompletedNCT047705061 country
- The Antibiotic Rifampin to Reduce High Levels of Blood and Urine Calcium in IIHStatus unknownNCT03384121Phase 11 country
- Recombinant Human rhPTH(1-34) VS Association Alfacalcidol/Hydrochlorothiazide in Severe Primary HypoparathyroidismCompletedNCT02824718Phase 21 country
- Safety and Efficacy of Chlorthalidone in Type 1 DiabetesTerminatedNCT03325114Phase 21 country
- Effects of Potassium Citrate in Urine of Children With Elevated Calcium in Urine and Kidney StonesWithdrawnNCT00120731Not applicable1 country
- Calciuric Effect and Cyclic Parenteral Nutrition in Preterm InfantsTerminatedNCT007117631 country
- Metabolic Workup in Patients Suffering From Kidney Stone Disease and OsteopeniaStatus unknownNCT04080973Not applicable1 country
- Comparison of the Impact of Diet vs Thiazide in BMD in Children With Idiopathic HypercalciuriaStatus unknownNCT03951558Not applicable1 country
- The Effects of Estrogen Replacement Therapy in Postmenopausal Women With Hypercalciuria and Low Bone MassTerminatedNCT01928082Phase 21 country
- Preterm Infants and NephrocalcinosisCompletedNCT024382671 country
- Vitamin D Supplementation in Older WomenCompletedNCT00472823Not applicable1 country
- ACTHAR GEL for Sarcoidosis-Associated Calcium Dysregulation: An Open-label Pilot StudyStatus unknownNCT02155803Phase 2/31 country
- Effect of Sodium Thiosulfate on Urine Chemistries of Hypercalciuric Stone FormersCompletedNCT01088555Not applicable1 country
- The Effect of Vitamin D Supplementation on Calcium Excretion in Thalassemia: a Dose Response StudyStatus unknownNCT01323608Phase 41 country
- Spironolactone to Decrease Potassium Wasting in Hypercalciurics on Thiazides DiureticsCompletedNCT00276289Not applicable1 country
- Low Salt Diet in Idiopathic HypercalciuriaCompletedNCT01005082Phase 2/31 country
- Phase III Randomized, Double-Blind Study of Potassium Phosphate Vs Potassium Citrate for Absorptive HypercalciuriaCompletedNCT00004284Phase 3