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Not yet recruitingNCT07882355Updated Oct 20, 2026

Diagnostic Work-up of Nephrocalcinosis in Children

An observational study in Nephrocalcinosis, sponsored by Assiut University. Not yet recruiting. Open to participants aged Up to 18 Years. Per ClinicalTrials.gov, last updated 2026-10-20.

Sponsored by Assiut University · Observational

Updated Oct 20, 2026Newly registeredGo to Updates ↓
Study type
Observational
Model
Case-only
Time perspective
Cross-sectional
Enrollment
40
Ages
Up to 18 Years
Sex
All
01

Study summary

This cross-sectional study aims to identify the underlying etiology of nephrocalcinosis and to evaluate the diagnostic work-up in infants and children presenting to Assiut University Children's Hospital.

Read the detailed description

Nephrocalcinosis is the deposition of calcium salts within the renal tubules and interstitium, most often detected by renal ultrasonography. In children, common causes include idiopathic hypercalciuria, hereditary tubulopathies, and prematurity-related factors.

This observational study will systematically evaluate the clinical, biochemical, urinary metabolic, radiological, and when indicated genetic findings in infants and children with nephrocalcinosis to determine the underlying etiology.

02

Conditions studied

  • Nephrocalcinosis

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Keywords

  • Nephrocalcinosis
  • Children
  • Hypercalciuria
  • Renal ultrasonography
  • Assiut
03

In context

Hypercalciuria

26 studies on the registry are indexed under Hypercalciuria; 5 are open to participants now.

Browse Hypercalciuria studies →

Lead sponsor

Assiut University is the lead sponsor of 5,050 studies on the registry; 2,174 are open to participants now.

Of its 14 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Up to 18 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Infants and children aged from birth to 18 years diagnosed with nephrocalcinosis by renal ultrasonography at Assiut University Children's Hospital.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • - Infants and children aged from birth to 18 years
  • Diagnosed with nephrocalcinosis by renal ultrasonography
  • Written informed consent from parent or legal guardian

Exclusion criteria

Exclusion Criteria:

  • Age above 18 years
  • End-stage renal disease already on renal replacement therapy
  • Refusal of informed consent by parents or caregivers
05

Study design

Observational model
Case-only
Time perspective
Cross-sectional
Enrollment
40 participants (estimated)
Patient registry
No

Groups and cohorts

  • Children with Nephrocalcinosis

    Infants and children with nephrocalcinosis undergoing systematic diagnostic work-up.

06

What researchers measure

Primary outcomes

  1. Number of children with identified etiology of nephrocalcinosis

    Number of children in whom a specific underlying etiology of nephrocalcinosis is identified after complete diagnostic work-up.

    Time frame: Baseline

Secondary outcomes

  1. Number of children with hypercalciuria

    Number of children with elevated spot urinary calcium/creatinine ratio.

    Time frame: Baseline

  2. Number of children with history of prematurity

    Number of children born preterm among those with nephrocalcinosis.

    Time frame: Baseline

  3. Number of children with history of furosemide exposure

    Number of children with documented prior exposure to furosemide.

    Time frame: Baseline

  4. Serum calcium level

    Mean serum calcium level in milligrams per deciliter.

    Time frame: Baseline

07

Study locations

No study locations are listed for this record.

08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

1 registry update since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Start is estimated for Oct 2026; primary completion for Oct 2027, 12 months later.

How these figures are worked out, and which studies are left out of them.

Registered
Oct 13, 2026
First posted
Oct 20, 2026
StartEst.
Oct 20, 2026
Primary completionEst.
Oct 20, 2027
CompletionEst.
Mar 1, 2028
Last update
Oct 20, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
Registered
First appeared on the registry. No changes since
Oct 20, 2026
Show all 1 update
  1. Oct 20, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07882355
Lead sponsor
Assiut University
Responsible party
Aya Ashraf Hanafy (Resident Physician, Department of Pediatrics, Assiut University) — Principal investigator
First posted
Oct 20, 2026
Start date
Oct 20, 2026 (estimated)
Primary completion
Oct 20, 2027 (estimated)
Completion
Mar 1, 2028 (estimated)
Last update
Oct 20, 2026

Study contacts

Aya A Hanafy, Resident
Contact
ayaa99426@gmail.com
+20 10 26206491
Ahlam B Ali, prof
study chair · Pediatrics Department, Assiut University Hospitals

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.

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