Hyperandrogenism clinical trials
The registry lists 81 studies for Hyperandrogenism across more than 10 countries. 22 are recruiting or about to start. 20 of them are mainly about Hyperandrogenism (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
University of Virginia (11) · Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal (3) · AGUNCO Obstetrics and Gynecology Centre (2) · National Institute of Environmental Health Sciences (NIEHS) (2) · Assistance Publique - Hôpitaux de Paris (2) · Royal College of Surgeons, Ireland (2) · Namsos Hospital (1) · Novartis Pharmaceuticals (1)
What is being tested here
Drugs under test in Hyperandrogenism studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Progesterone | 3 | 0 | 6 |
| Spironolactone | 2 | 0 | 3 |
| Metformin | 1 | 1 | 8 |
| Osilodrostat | 1 | 0 | 1 |
| Cabergoline | 1 | 0 | 1 |
| Bicalutamide | 1 | 0 | 1 |
| Magnesium | 1 | 0 | 1 |
| Carnitine | 1 | 0 | 1 |
| Inositol | 0 | 0 | 4 |
| Drospirenone and ethinyl estradiol combination | 0 | 0 | 2 |
Drug classes tested here Mineralocorticoid receptor antagonists (MRAs) 2 open · Antiandrogens 1 open · Estrogens 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 2
- Apr 2027Biomarker Panel for PCOS-Associated Liver Steatosis in Adolescent Girls (COMPASS-pedPCOS) · Kayseri City Hospital
- Sep 2027Evaluation of Circadian Hormonal Balance: LC-MS/MS Measurement of Salivary and Serum Steroids in Patients With Congenital Adrenal Hyperplasia · Assistance Publique - Hôpitaux de Paris
Who these studies take
Of the 15 Hyperandrogenism studies recruiting now, 1 (7%) set no upper age limit and 14 (93%) stop at 75 or younger. 8 (53%) take children under 18. 13 (87%) are for women only and 0 (0%) for men only; 10 (67%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 6 (40%) | 1 (7%) |
| 18 | 8 (53%) | 2 (13%) |
| 30 | 7 (47%) | 1 (7%) |
| 40 | 7 (47%) | 1 (7%) |
| 50 | 2 (13%) | 0 (0%) |
| 65 | 2 (13%) | 0 (0%) |
| 75 | 1 (7%) | 0 (0%) |
| 85 | 1 (7%) | 0 (0%) |
Across all 81 studies, recruiting or not: 90% stop at 75 or younger and 89% at 65; 36% take children; 90% are for women only and 0% for men only; 42% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Hyperandrogenism studies take
Of 12 interventional studies with no phase under Hyperandrogenism, half reached primary completion within 13 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 13 mo9–65 · 12 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Results posted1
- Inositol Supplementation to Treat PCOS (INSUPP-PCOS)Oct 28, 2026NCT03864068
Newly registered1
- Efficacy of Metformin With and Without Probiotics in Women With PCOSOct 15, 2026NCT07874646
Studies
Recruiting first, then most recently updated. Showing 50 of 81. Browse all 81 → or search them.
- Polycystic Ovary Syndrome in Type 1 DiabetesRecruitingNCT074909641 country
- Lean Beef as Part of a Healthy Meal Plan in Adolescents With Polycystic Ovary Syndrome (PCOS)/Polyendocrine Metabolic Ovarian Syndrome (PMOS)RecruitingNCT07780188Not applicable1 country
- This Study Aims to Evaluate Whether Milamend's Product Could Improve Hormone Balance in Women Who Suffer From Self-reported PCOS Symptoms.RecruitingNCT07764328Not applicable1 country
- Biomarker Panel for PCOS-Associated Liver Steatosis in Adolescent Girls (COMPASS-pedPCOS)Not yet recruitingNCT077313731 country
- Evaluation of Serum Preptin Levels in Patients With Polycystic Ovary SyndromeNot yet recruitingNCT07736079
- Evaluation of Circadian Hormonal Balance: LC-MS/MS Measurement of Salivary and Serum Steroids in Patients With Congenital Adrenal HyperplasiaNot yet recruitingNCT077182301 country
- Combination Osilodrostat and Cabergoline in Cushing's DiseaseEnrolling by invitationNCT07603466Phase 41 country
- Effect of Magnesium and Levocarnitine on Metabolic and Clinical Outcomes in Women With Polycystic Ovarian Syndrome (PCOS)RecruitingNCT07298564Not applicable1 country
- Combined Use of Machine Learning and Metabolomics to Improve the Diagnosis and Management of HyperandrogenismNot yet recruitingNCT07253454
- Cardiovascular and Endothelial Markers During OGTT Before and at Six and Twelve Months Post-treatment in Women With PCOSRecruitingNCT068894541 country
- Does Spironolactone Normalize Sleep-wake Luteinizing Hormone Pulse Frequency in Pubertal Girls With Hyperandrogenism?RecruitingNCT04723862Early Phase 11 country
- Hyperandrogenemia and Altered Day-night LH Pulse PatternsRecruitingNCT03068910Early Phase 11 country
- Acute Progesterone Suppression of Wake vs. Sleep Luteinizing Hormone Pulse Frequency in Pubertal Girls With and Without HyperandrogenismRecruitingNCT00929006Early Phase 11 country
- International Registry of Congenital Portosystemic Shunt (IRCPSS)Enrolling by invitationNCT0604190616 countries
- Acupuncture or Metformin for Insulin Resistance in Women With PCOSRecruitingNCT02647827Phase 22 countries
- FEmale Metabolic Risk and Androgens: an Irish Longitudinal (FEMAIL) StudyRecruitingNCT049126481 country
- Offspring Born to Mothers With Polycystic Ovary Syndrome in Guangzhou Cohort StudyRecruitingNCT037420111 country
- Suppression of Daytime and Nighttime Luteinizing Hormone Frequency by ProgesteroneRecruitingNCT01428089Phase 11 country
- Assessment of Day-night Secretion of Progesterone and LH Across PubertyRecruitingNCT021559331 country
- Does Treatment of Androgen Excess Using Spironolactone Improve Ovulatory Rates in Girls With Androgen Excess?RecruitingNCT04075149Early Phase 11 country
- Phenotype and Epidemiology of the Polycystic Ovary Syndrome (PCOS) in Colombia (PEP - Colombia) Study.RecruitingNCT059261151 country
- The RolE oF Androgen Excess in MUscle Energy MetaboLism in Women With PolyCystic Ovary Syndrome (REFUEL PCOS) Study 2Not yet recruitingNCT05647356Not applicable1 country
- Inositol Supplementation to Treat PCOS (INSUPP-PCOS)CompletedNCT03864068Phase 21 country
- Efficacy of Metformin With and Without Probiotics in Women With PCOSCompletedNCT07874646Not applicable1 country
- Body Fat as Determinant of Female Gonadal DysfunctionCompletedNCT038419811 country
- Myo-Inositol and D-Chiro-Inositol for Menstrual Irregularities and Hormone Changes in Women With Polycystic Ovarian SyndromeCompletedNCT07701525Phase 41 country
- Effect of Hyperandrogenism on IVF Outcomes in PCOS PatientsTerminatedNCT055556801 country
- Continuous Versus Cyclical OCP Use in PCOSCompletedNCT03819140Phase 41 country
- Steroid Profiles in PCOS and Effect of OCP TreatmentCompletedNCT071614401 country
- Treating Inflammation in Polycystic Ovary Syndrome to Ameliorate Ovarian DysfunctionCompletedNCT03229408Phase 21 country
- Prevalence of Hyperandrogenism in Type 1 DiabetesCompletedNCT049793771 country
- Androgen Excess as a Cause for Adipogenic Dysfunction in PCOS WomenCompletedNCT01889199Phase 21 country
- Metformine and CC Compared With Placebo and CC for Induction Ovulation in PCOS Patients With Insulin ResistantTerminatedNCT02523898Phase 2
- Urinary DENND1A.V2 as a Predictor of Pubertal HyperandrogenemiaSuspendedNCT026111281 country
- Ovarian Contribution to Androgen Production in Adolescent GirlsActive, not recruitingNCT01421810Not applicable1 country
- Mechanisms of Blood Pressure Dysfunction in Transmen Receiving TestosteroneWithdrawnNCT04524325Not applicable
- Phlebotomy and Polycystic Ovary SyndromeCompletedNCT02460445Not applicable1 country
- Sleep-wake Changes of Luteinizing Hormone Frequency in Pubertal Girls With and Without High TestosteroneStatus unknownNCT009300071 country
- Lactobacillus Rhamnosus and PCOS TreatmentCompletedNCT03902301Not applicable1 country
- Eastern Siberia PCOS Epidemiology & Phenotype StudyCompletedNCT051943841 country
- Ketogenic Diet in PCOS With Obesity and Insulin ResistanceCompletedNCT04801173Not applicable1 country
- Metabolic Profile and Adipokine Levels in Young Hyperandrogenemic FemalesStatus unknownNCT051120291 country
- Comparison of Serum C Type Natriuretic Peptide Levels Between Polycystic Ovary Syndrome Patients and Healthy WomenCompletedNCT04006171Not applicable1 country
- Ovarian Response to Recombinant Follicle Stimulating Hormone in Women With PCOSCompletedNCT03252223Phase 41 country
- Myo-inositol, Alpha-Lactalbumin and Folic Acid Treatment in PCOSCompletedNCT04645745Not applicable2 countries
- Effect of Metformin on Sensitivity of the GnRH Pulse Generator to Suppression by Estradiol and ProgesteroneCompletedNCT01427595Not applicable1 country
- Study of Pharmacodynamics of LIK066 in Overweight and Obese Women With Polycystic Ovary SyndromeCompletedNCT03152591Phase 22 countries
- The Effect of Ibuprofen on Women With PCOS.Status unknownNCT04485403Phase 21 country
- Treatment of Obesity With Topiramate in Patients With Polycystic Ovary SyndromeStatus unknownNCT04453306Phase 41 country
- Insulin Differences Between African-American and Caucasian Female Adolescents With Polycystic Ovary Syndrome (PCOS)TerminatedNCT02052479Not applicable1 country