Endocrine System Diseases clinical trials
The registry lists 322 studies for Endocrine System Diseases across more than 10 countries. 51 are recruiting or about to start. 47 of them are mainly about Endocrine System Diseases (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06. Counting its 111 narrower conditions too, such as Diabetes Mellitus, Type 2: 37,015 studies, 6,733 open.
Get an email when these change. Save the Endocrine System Diseases studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Status
Who runs them
National Center for Research Resources (NCRR) (26) · Eli Lilly and Company (13) · University of Pittsburgh (8) · AstraZeneca (7) · Pfizer (6) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (6) · University Hospital, Basel, Switzerland (5) · Merck Sharp & Dohme LLC (5)
What is being tested here
Drugs under test in Endocrine System Diseases studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Drug classes tested here GLP-1 receptor agonists 2 open · Tyrosine kinase inhibitors (TKIs) 2 open · Androgens 2 open · SGLT2 inhibitors 7 · DPP-4 inhibitors 7
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- May 2027A Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes Who Observe Ramadan Fasting · Phase 3 · Eli Lilly and Company
- Jun 2027A Phase 3 Randomized Clinical Trial to Investigate the Safety and Efficacy of Palopegteriparatide at Doses Greater Than 30 μg/Day in Adult Participants With Hypoparathyroidism · Phase 3 · Ascendis Pharma Bone Diseases A/S
- Oct 2027A Study to Learn About the Study Medicine (PF-08653944) in People With Obesity or Overweight and Type 2 Diabetes (T2D) · Phase 3 · Pfizer
- Nov 2026Observational Study for the Characterisation of Patients Affected by Any Type of Diabetes and Endocrine Disorders · IRCCS San Raffaele
- Nov 2026Breaking Silence Through Story: A Narrative Medicine Intervention for Parents of Children With Urogenital Conditions · Sarah Schlegel
- Nov 2026Rising Tide - Amniotic Tissue(s) Treatments for Chronic Diabetic Foot Ulcers · Tides Medical
- Nov 2026Clinical Trial Assessing Human Placental Membrane Products and Standard of Care Versus Standard of Care in Nonhealing DFUs and VLUs · C5 Biomedical
- Dec 2026Evaluating a Digital Intervention for Alleviating Diabetes-specific Emotional Distress in Adults Living With T2DM · Gaia AG
- Dec 2026Telehealth Music Therapy for Adults With Endocrine Disorder and Depression · Appalachian State University
- Dec 2026Environment, Inflammation and Metabolic Diseases Study · Qifu Li
Who these studies take
Of the 42 Endocrine System Diseases studies recruiting now, 20 (48%) set no upper age limit and 15 (36%) stop at 75 or younger. 10 (24%) take children under 18. 4 (10%) are for women only and 2 (5%) for men only; 10 (24%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 7 (17%) | 7 (17%) |
| 18 | 37 (88%) | 36 (86%) |
| 30 | 37 (88%) | 36 (86%) |
| 40 | 37 (88%) | 36 (86%) |
| 50 | 33 (79%) | 35 (83%) |
| 65 | 33 (79%) | 35 (83%) |
| 75 | 27 (64%) | 29 (69%) |
| 85 | 25 (60%) | 27 (64%) |
Across all 322 studies, recruiting or not: 52% stop at 75 or younger and 37% at 65; 24% take children; 12% are for women only and 6% for men only; 25% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Endocrine System Diseases studies take
Of 29 phase 3 interventional studies under Endocrine System Diseases, half reached primary completion within 26 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 2 | 39 mo23–49 · 19 studies | — | — |
| Phase 3 | 26 mo17–36 · 29 studies | 25 mo17–34 · 27 studies | — |
| Interventional, no phase | 23 mo11–35 · 52 studies | — | 23 mo11–39 · 45 studies |
| Observational | 43 mo13–339 · 32 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting2
Results posted1
- Day and Night Closed-loop in Young People With Type 1 DiabetesOct 15, 2026NCT02925299
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 50 of 322. Browse all 322 → or search them.
- Anticipated Stigma, Illness Identity, and Quality of Life in Male HypogonadismRecruitingNCT077525111 country
- A Phase 3 Randomized Clinical Trial to Investigate the Safety and Efficacy of Palopegteriparatide at Doses Greater Than 30 μg/Day in Adult Participants With HypoparathyroidismRecruitingNCT07081997Phase 31 country
- A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or ObesityRecruitingNCT07595549Phase 311 countries
- Trial Investigating the Efficacy and Safety of Weekly Lonapegsomatropin Compared to Daily Somatropin in Children and Adolescents With Short Stature or Growth Failure Due to Growth Hormone Sufficient DisordersRecruitingNCT07221851Phase 37 countries
- Observational Study for the Characterisation of Patients Affected by Any Type of Diabetes and Endocrine DisordersRecruitingNCT072068751 country
- Study of Endocrine-Related Conditions and PhysiologyRecruitingNCT038674481 country
- Evaluation of ETHY-001 for Safety, Tolerability, and Clinical Activity in Thyroid Eye DiseaseRecruitingNCT07885605Phase 11 country
- Evaluation of Children With Endocrine and Metabolic-Related ConditionsRecruitingNCT027699751 country
- The diabEAT Study: Insulin dElivery Technologies And eaTing Behaviours in People With Type 1 DiabetesRecruitingNCT073484321 country
- Diagnosis of PheochromocytomaRecruitingNCT00004847Phase 11 country
- A Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes Who Observe Ramadan FastingRecruitingNCT07613307Phase 34 countries
- Glycemic Control and Quality of Life Evolution for Patients With T1D Using the myLoop Powered by CamAPS FX System in Combination With FreeStyle Libre 3 / 3 Plus Sensors in FranceNot yet recruitingNCT07835685
- Evaluation of Adults With Endocrine and Metabolic-Related ConditionsRecruitingNCT028303081 country
- Acute Metabolic Effects of Tirzepatide in Type 1 DiabetesRecruitingNCT06820281Phase 21 country
- METabolic MODulation to Enhance Insulin Sensitivity and Mitochondrial Function in Type 1 Diabetes (MetMod-T1D)RecruitingNCT07699380Phase 22 countries
- Exhaled Breath Electronic Nose for Multi-Disease Risk PrescreeningNot yet recruitingNCT07804017
- Transition of Care in Pediatric Rare Endocrine DisordersRecruitingNCT07786142Not applicable1 country
- Understanding New Cachexia Subtypes Through Observational Epidemiological ResearchRecruitingNCT077763531 country
- Bao Yuan Tang Extract and Galactooligosaccharides for Sleep RegulationNot yet recruitingNCT07774897Not applicable1 country
- Testosterone Therapy With or Without Finasteride After Spinal Cord Injury: TRT-SCI TrialNot yet recruitingNCT07742553Phase 2/31 country
- Study of BHV-1300 in Graves' DiseaseRecruitingNCT06980649Phase 12 countries
- Telehealth Music Therapy for Adults With Endocrine Disorder and DepressionRecruitingNCT07413874Not applicable1 country
- Myokines as Potential Biomarkers and Drivers of Sarcopenia in Metabolic and Endocrine DiseasesRecruitingNCT077036831 country
- A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 RearrangementsRecruitingNCT03093116Phase 1/219 countries
- Breaking Silence Through Story: A Narrative Medicine Intervention for Parents of Children With Urogenital ConditionsRecruitingNCT06989593Not applicable1 country
- Environment, Inflammation and Metabolic Diseases StudyRecruitingNCT075126091 country
- Intra Ovarian Muse Cell Injection for Perimenopause Symptom Relief and Ovarian Function Restoration (MUSE-OVARY)Enrolling by invitationNCT075116601 country
- New Clinical Decision Support Score Based on Steroid Hormone Profiling in the Diagnosis of MACSRecruitingNCT073525271 country
- Phenotyping of Patients With Polycystic Ovary SyndromeRecruitingNCT073399301 country
- Prospective Cohort of Integrated Traditional Chinese and Western Medicine in ChinaNot yet recruitingNCT07196917
- Implementation of Support in the Care of Adults Living With Type 1 DiabetesRecruitingNCT06069583Not applicable1 country
- Rare and Atypical Diabetes NetworkRecruitingNCT055442661 country
- Locomotor Training With Testosterone to Promote Bone and Muscle Health After Spinal Cord InjuryRecruitingNCT04460872Phase 21 country
- Extension Study of Two Doses of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED)RecruitingNCT06112340Phase 2/31 country
- Rising Tide - Amniotic Tissue(s) Treatments for Chronic Diabetic Foot UlcersRecruitingNCT06681428Not applicable1 country
- Clinical Trial Assessing Human Placental Membrane Products and Standard of Care Versus Standard of Care in Nonhealing DFUs and VLUsRecruitingNCT06674980Not applicable1 country
- In-Person Lifestyle Program for Black Adolescent Girls at Risk for Type 2 DiabetesRecruitingNCT06557317Not applicable1 country
- A Multicentre Study on Features of the Gut Microbiota of Patients With Critical Chronic Diseases in ChinaRecruitingNCT056382691 country
- Effectiveness of CBT in Improving Psycho-Neuro-Endocrine Factors in Women Following In Vitro Fertilization ProgramRecruitingNCT06521957Not applicable1 country
- Cardiovascular and Endocrine Response to Muscular Training Program of Young Soccer Players Aged 14-18 YearsNot yet recruitingNCT06451367Not applicable
- Neuroendocrine Mechanisms in Adiposity: An Integrated Approach to the Characterization of Potential Pharmacological Novel Targets Based on Experimental and Clinical ModelsNot yet recruitingNCT06326853
- OSPREY is a Post-market, Global, Multicentre, Observational, Prospective Registry.RecruitingNCT044936322 countries
- Offspring Born to Mothers With Polycystic Ovary Syndrome in Guangzhou Cohort StudyRecruitingNCT037420111 country
- "Iron Overload and Endocrinological Diseases"RecruitingNCT061370791 country
- Efficacy and Safety of Android Artificial Pancreas System in Adult Patients With Type 1 Diabetes Mellitus in ChinaRecruitingNCT05726461Not applicable1 country
- Dissecting the IMpact of 11-OXygenated and Classic Androgens on Skeletal Muscle Insulin Sensitivity (DIMOXIS)RecruitingNCT05263557Not applicable1 country
- Phenotype and Epidemiology of the Polycystic Ovary Syndrome (PCOS) in Colombia (PEP - Colombia) Study.RecruitingNCT059261151 country
- Spanish Series of Patients Treated With the Radionuclide Lutetium177RecruitingNCT049492821 country
- Personalized Follow-up Program in the Type 2 Diabetes PreventionNot yet recruitingNCT04907760Not applicable
- Comprehensive Data Collection and Follow-Up for Patients With Thyroid, Parathyroid and Adrenal DiseaseRecruitingNCT030507621 country