Gingivitis clinical trials
The registry lists 631 studies for Gingivitis across more than 10 countries. 107 are recruiting or about to start. 419 of them are mainly about Gingivitis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
ClinicalTrials.gov finds 695 studies for Gingivitis. How that becomes 630 here
This page counts the studies the registry files under Gingivitis, and those it files under no condition that list Gingivitisthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 695Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −16List Gingivitis as a condition, but the registry did not file them under itMost often written as “Plaque Induced Gingivitis” (6), “Dental Plaque Induced Gingivitis” (2), and “Gingivitis Infection” (2). The registry filed them under other conditions only, most often Dental Plaque (10) and Plaque, Amyloid (4).
- −49Match it another way37 name it in the title, 2 in a keyword, and 10 by a synonym or other text the search reads.
- 630The count on this page23 of them list Gingivitis in their own words; the registry filed them under no condition.
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Status
Who runs them
Colgate Palmolive (44) · Procter and Gamble (22) · HALEON (12) · Inonu University (12) · Cairo University (10) · Abant Izzet Baysal University (8) · GlaxoSmithKline (8) · Postgraduate Institute of Dental Sciences Rohtak (6)
What is being tested here
Drugs under test in Gingivitis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Nov 2026To Assess the Efficacy of Two Brushing Regimens: in the Reduction of Established Dental Plaque and Gingivitis. · Phase 3 · Colgate Palmolive
- Dec 2026Effectiveness of Toothpaste Tablets on Plaque, Gingival Health and Caries Experiences · Phase 3 · Loma Linda University
- Jan 2027Clinical Evaluation of a Toothpaste for Dental Plaque Reduction and Prevention of Gum Problems · Phase 3 · Colgate Palmolive
- Apr 2027Clinical Study Examining the Control of Plaque and Gingivitis · Phase 3 · Colgate Palmolive
- Nov 2026Evaluation of a Toothpaste Containing a Gum Health Active in Participants With Gingival Problem · Unilever R&D
- Nov 2026NOVOSYN® Quick Versus MONOSYN® Quick Suture Material in Resective Periodontal Surgery · Aesculap AG
- Nov 2026A Study Investigating Gingival Crevicular Fluid Biomarkers Following Use of a Commercially Available Toothpaste Containing Stannous Fluoride · HALEON
- Nov 2026Treatment Outcome of Elastomeric and Nickel-Titanium Separators in Tooth Separation · 3D-Aligners
- Nov 2026HALP Score, Blood-Based Inflammatory Indices, and Salivary MMP-8 in Periodontal Disease and Healing After Non-Surgical Therapy · Ömer Faruk Okumuş
- Nov 2026Oil Pulling Reduction · The University of Texas Health Science Center at San Antonio
Who these studies take
Of the 53 Gingivitis studies recruiting now, 15 (28%) set no upper age limit and 36 (68%) stop at 75 or younger. 11 (21%) take children under 18. 5 (9%) are for women only and 0 (0%) for men only; 35 (66%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 4 (8%) | 3 (6%) |
| 18 | 46 (87%) | 41 (77%) |
| 30 | 42 (79%) | 37 (70%) |
| 40 | 42 (79%) | 37 (70%) |
| 50 | 39 (74%) | 36 (68%) |
| 65 | 37 (70%) | 34 (64%) |
| 75 | 17 (32%) | 14 (26%) |
| 85 | 17 (32%) | 14 (26%) |
Across all 631 studies, recruiting or not: 70% stop at 75 or younger and 54% at 65; 19% take children; 5% are for women only and 1% for men only; 72% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Gingivitis studies take
Of 35 phase 3 interventional studies under Gingivitis, half reached primary completion within 3 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 4 mo2–7 · 11 studies | — | — |
| Phase 2 | 2 mo1–15 · 16 studies | — | — |
| Phase 3 | 3 mo2–6 · 35 studies | 3 mo2–6 · 23 studies | — |
| Phase 4 | 3 mo2–4 · 25 studies | — | — |
| Interventional, no phase | 7 mo3–15 · 257 studies | 3 mo1–5 · 53 studies | 9 mo4–18 · 204 studies |
| Observational | 12 mo5–25 · 30 studies | — | 12 mo5–25 · 30 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Started recruiting1
Results posted1
Newly registered10
- The Effect of Using Plaque-disclosing Tablets on the Effectiveness of Toothbrushing and Gingival Health in ChildrenNov 9, 2026NCT07924423
- Efficacy of Two Brushing Regimens in the Reduction of Established Dental Plaque and GingivitisNov 4, 2026NCT07917507
- Efficacy of Thymus Vulgaris Mouthwash in the Management of Biofilm-Induced GingivitisOct 29, 2026NCT07905456
- Effectiveness of Oil Pulling Using Oils in Comparison With Mouthwash for GingivitisOct 23, 2026NCT07892235
- Alpha-Lipoic Acid as an Adjunct to Non-Surgical Periodontal Treatment in GingivitisOct 20, 2026NCT07882394
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- Individualized Management of Plaque-Related Gingival Inflammation in Routine Dental PracticeOct 20, 2026NCT07882459
- St. John's Wort Oil Versus Chlorhexidine Mouthwash for Gingival Problems After Rapid Maxillary ExpansionOct 20, 2026NCT07882771
- Comparision of Enzymatic and Active Salt ToothpasteOct 19, 2026NCT07880483
- Prevalence and Associated Factors of High BMI and Periodontitis in Thai Adults Aged Under 60 YearsOct 19, 2026NCT07880717
- Salivary and GCF Biomarkers in Periodontal Health, Gingivitis and PeriodontitisOct 19, 2026NCT07881406
Studies
Recruiting first, then most recently updated. Showing 50 of 631. Browse all 631 → or search them.
- Effectiveness of Coconut Oil Pulling and Moringa Mouthwash Versus Chlorhexidine in Reducing Gingivitis in Diabetic ChildrenNot yet recruitingNCT07826390Not applicable1 country
- NOVOSYN® Quick Versus MONOSYN® Quick Suture Material in Resective Periodontal SurgeryRecruitingNCT05813236Not applicable1 country
- Comparison of the Effects of Oral Hygiene Regimens on Clinical, Immunomodulatory, and Microbial Outcomes and Oral Tolerance in People With GingivitisEnrolling by invitationNCT07501455Not applicable1 country
- Efficacy of Thymus Vulgaris Mouthwash in the Management of Biofilm-Induced GingivitisNot yet recruitingNCT07905456Phase 21 country
- Periodontal Disease and Small Vulnerable Newborns in Rural Nepal: A Community-based TrialNot yet recruitingNCT07553286Phase 3
- Effectiveness of Oil Pulling Using Oils in Comparison With Mouthwash for GingivitisNot yet recruitingNCT07892235Not applicable1 country
- Circadian Clock Proteins in Gingival Crevicular Fluid of Individuals With and Without Circadian Rhythm DisruptionNot yet recruitingNCT075920521 country
- Salivary and GCF Biomarkers in Periodontal Health, Gingivitis and PeriodontitisNot yet recruitingNCT078814061 country
- Individualized Management of Plaque-Related Gingival Inflammation in Routine Dental PracticeNot yet recruitingNCT07882459Not applicable1 country
- Alpha-Lipoic Acid as an Adjunct to Non-Surgical Periodontal Treatment in GingivitisRecruitingNCT07882394Not applicable1 country
- The Study to Evaluate the Plaque Control and Anti-Gingivitis Efficacy of a Toothpaste in Chinese PopulationRecruitingNCT07816406Not applicable1 country
- Comparative Evaluation of the Anti-Plaque and Anti-Gingivitis Effects of Nanobiofusion Gingival Gel (NBF), Placebo Gel, and Commercial ToothpasteNot yet recruitingNCT07850232Not applicable1 country
- Prevalence and Associated Factors of High BMI and Periodontitis in Thai Adults Aged Under 60 YearsRecruitingNCT078807171 country
- Taste Acceptance and Effectiveness of Hyaluronic Acid and Chlorhexidine Mouthwashes in Children With GingivitisNot yet recruitingNCT07662226Phase 11 country
- A Study Investigating Gingival Crevicular Fluid Biomarkers Following Use of a Commercially Available Toothpaste Containing Stannous FluorideRecruitingNCT07842042Not applicable1 country
- CHEER Oral Health in Pregnancy StudyRecruitingNCT07377344Not applicable1 country
- Effectiveness of Interactive Techniques on Oral Hygiene Skills in a Group of Autistic Egyptian ChildrenNot yet recruitingNCT07859696Not applicable
- Retinal and Choroidal Changes in Periodontal DiseaseNot yet recruitingNCT078569011 country
- Clinical Study Examining the Control of Plaque and GingivitisNot yet recruitingNCT07842978Phase 31 country
- Clinical Evaluation of a Toothpaste for Dental Plaque Reduction and Prevention of Gum ProblemsRecruitingNCT07842991Phase 31 country
- Xylitol and the Prevention of Periodontal Disease and Preterm Birth TrialRecruitingNCT07424846Phase 2/31 country
- Integrated Diabetes and Oral Health Care in OmanNot yet recruitingNCT07809477Not applicable
- Oral Hygiene Assistance Training ProgramNot yet recruitingNCT07807397Phase 4
- Clinical Assessment of the Safety and Efficacy of Flaus Electric Flosser on Plaque and Gingivitis Compared to a Manual ToothbrushNot yet recruitingNCT07805148Not applicable1 country
- Efficacy of Oral Hygiene Regimens in Patients Undergoing Non-Surgical Periodontal TreatmentNot yet recruitingNCT07803484Phase 31 country
- Investigation of the Interplay Between Local Oral Inflammation, Microbiota and Systemic Immune Responses.Not yet recruitingNCT06966492Phase 41 country
- Oil Pulling ReductionRecruitingNCT07706647Not applicable1 country
- Safety and Efficacy of Flaus Electric Flosser on Plaque and Gingivitis Compared to a Manual ToothbrushRecruitingNCT07779564Not applicable1 country
- Evaluation of the Safety and Efficacy of SALI-10 Probiotic LozengesRecruitingNCT07508839Not applicable1 country
- Evaluation of Toothbrush BristlesRecruitingNCT07306026Not applicable1 country
- New Functional Ingredient for Oral CareNot yet recruitingNCT07771907Not applicable1 country
- Stingless Bee Honey Mouth Rinse on GingivitisNot yet recruitingNCT07461155Early Phase 1
- Digital vs Conventional VFR in Post-Orthodontic RetentionNot yet recruitingNCT07760935Not applicable
- Bacterial Diversity Study Using 16S rRNA Sequencing of Periodontal Samples From Patients With Orthodontic RetainersRecruitingNCT07718061Not applicable1 country
- Reducing Risk for Infective EndocarditisRecruitingNCT05721781Not applicable1 country
- A Multicentre Randomised Controlled Trial Evaluating the Efficacy of the SMILE™ Module for Improving Short-term Periodontal Outcomes, Compliance, and Acceptability Among Clinical Dental StudentsNot yet recruitingNCT07702383Not applicable1 country
- Effectiveness of Toothpaste Tablets on Plaque, Gingival Health and Caries ExperiencesNot yet recruitingNCT07124533Phase 31 country
- Effects of Using Miswak in Addition to Oral Hygiene Products in Patients With GingivitisNot yet recruitingNCT076897861 country
- Bio-Descaling Toothpaste for Dental Calculus ReductionNot yet recruitingNCT07689071Not applicable
- A Person-centered, Theory-based, Intervention - Method Development Through the Integration of Digital Technology.Enrolling by invitationNCT07306117Not applicable1 country
- Salivary Biomarkers in Periodontal Disease ProgressionRecruitingNCT076617841 country
- Intraoral Scanners as Periodontal and Dental Pathologies Diagnosis ToolsRecruitingNCT06006429Not applicable1 country
- Theranovis Dental Gel in Patients With GingivitisNot yet recruitingNCT07641192Not applicable1 country
- Evaluation of Gingival Crevicular Fluid Cytokine Profiles in Children and Young Adults With GingivitisRecruitingNCT076076391 country
- The Effect of Vitamin D Supplementation on the Anti-inflammatory Response in Periodontal DiseasesRecruitingNCT07636733Not applicable1 country
- Clinical Study to Collect and Analyze Dental Plaque and Oral Health Measures in a Population With High Plaque/Low Gingivitis and High Plaque/High GingivitisRecruitingNCT07614490Phase 41 country
- Treatment Outcome of Elastomeric and Nickel-Titanium Separators in Tooth SeparationNot yet recruitingNCT07591454Not applicable
- Evaluation of the Effect of the Toothpaste on Delicate GumsRecruitingNCT07494747Not applicable1 country
- Development of A Self-Assessment Tool for Personalized Preventive Periodontal Care Among the Saudi Population Using Semi-Supervised LearningRecruitingNCT074103511 country
- Air-polishing With Erythritol During Orthodontic TretamentRecruitingNCT05989750Not applicable1 country