An interventional study of Gingivitis toothpaste and Regular toothpaste in Gingivitis, sponsored by Lacer S.A.. Recruiting at 1 site in Spain. Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2026-05-14.
Sponsored by Lacer S.A. (part of Italfarmaco) · Not applicable, Interventional, and Treatment
The goal of this study is to learn if a toothpaste works to alleviate gingivitis in adults. It will also learn about the safety of the product. The main question it aims to answer is:
Participants will:
631 studies on the registry are indexed under Gingivitis; 107 are open to participants now.
This study's planned enrollment of 60 is close to the median of 66 across 507 interventional studies indexed under Gingivitis.
Browse Gingivitis studies →Lacer S.A. is the lead sponsor of 13 studies on the registry; 5 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Subjects clinically showing moderate gums inflammation (gingivitis grade II, in particular all gingival scores for the mean should be between 1.75 and 2.3, according to Löe and Silness gingival scoring system), in particular:
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
A planned gap after a treatment, so that its effects can lessen before the study treatment or a study assessment. Ask the study team and the doctor who prescribed it before changing any medicine.
Able to become pregnant: from the first period until menopause, unless permanently unable to through surgery (removal of the womb, or of both ovaries or both fallopian tubes).
Criteria for people of childbearing potential usually ask for a negative pregnancy test and for contraception during the study and for a time after it.
Washout period
A planned gap after a treatment, so that its effects can lessen before the study treatment or a study assessment. Ask the study team and the doctor who prescribed it before changing any medicine.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Childbearing potential
Able to become pregnant: from the first period until menopause, unless permanently unable to through surgery (removal of the womb, or of both ovaries or both fallopian tubes).
Criteria for people of childbearing potential usually ask for a negative pregnancy test and for contraception during the study and for a time after it.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Other: Gingivitis toothpaste
Other: Regular toothpaste
Subjects will use the gingivitis toothpaste 2-3 times daily during 4 weeks
Subjects will use the regular toothpaste 2-3 times daily during 4 weeks
Change from Baseline in the Gingival Index at 1 month
Time frame: From baseline to end of treatment at 1 month
Change in plaque index at 1 month
Time frame: From baseline to end of use at 1 month
Plan to share: No — Only summary of the results to support the publication will be shared. No complete study documents will shared.
Started Mar 2026 (actual). Primary completion is estimated for Sep 2026, 6 months after the start.
Of 53 industry-sponsored interventional studies with no phase under Gingivitis, half reached primary completion within 3 months of starting (the median), counting those still running; a quarter within 1 and three quarters within 5. This study's planned 6 months is above that.
Counting every sponsor, half of 257 studies reached it within 7 months; a quarter within 3 and three quarters within 15.
How these figures are worked out, and which studies are left out of them.
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
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