Toothpaste clinical trials
How each study uses Toothpaste is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
Get an email when these change. Save the Toothpaste studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Approvals
The first approval found in each region, with its record
- United States
- Not in FDA's approval records
- European Union
- Not in EMA's list of EU-wide authorisations
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
How studies write it
Studies that test it under each name
Studies by the year they started
8 studies that test it; most in 2023 (3)
| Year | Studies |
|---|---|
| 2011 | 2 |
| 2020 | 2 |
| 2023 | 3 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 1 · Other 7
Loma Linda University (2) · University of Campinas, Brazil (2) · Massimo Corsalini (1) · Colgate Palmolive (1) · Riyadh Elm University (1) · University of Catania (1)
Often tested with
Tested in the same studies.
Coming up
From the study records. Dates are the sponsors’ own estimates and often move.
Reaching primary completion within a year · 1, 1 in phase 3
Studies that test Toothpaste, phase 3 first.
- Dec 2026Effectiveness of Toothpaste Tablets on Plaque, Gingival Health and Caries ExperiencesPhase 3 · Loma Linda University
Studies
Open first, then newest update. How each study uses Toothpaste is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 8
- Effectiveness of Toothpaste Tablets on Plaque, Gingival Health and Caries ExperiencesNot yet recruitingPhase 3Loma Linda UniversityNCT07124533Written as Toothpaste Tablet
- Toothpaste With Sodium Carbonate in Patients With GingivitisRecruitingNot applicableUniversity of CataniaNCT06224699Written as Toothpaste Product
- Probiotics And Ozonated Olive Oil To Maintain Oral Eubiosis In Stage I And II Periodontitis PatientsCompletedNot applicableMassimo CorsaliniNCT06955546Written as Toothpaste Product
- Efficacy of Eco-Friendly Toothpaste Tablets Versus Conventional Toothpaste Using PI and GI IndexCompletedPhase 3Loma Linda UniversityNCT05805865Written as Toothpaste Tablet
- Measurement of Viral Load Reduction in the Oral Cavity After a Regimental Use of OC Toothpaste ProductsCompletedPhase 3Colgate PalmoliveNCT04864925Written as Colgate Total Clean Mint
- Efficacy of Miswak in Oral Hygiene MaintenanceCompletedPhase 4Riyadh Elm UniversityNCT04561960Written as Toothpaste Product
- Anticaries Potential and Fluorosis Risk From Different Fluoride ToothpastesCompletedPhase 1University of Campinas, BrazilNCT01589991Written as Toothpaste
- Fluoride Availability in Saliva After Use of Sodium Fluoride or Monofluorophosphate ToothpastesCompletedPhase 1University of Campinas, BrazilNCT01589458Written as Toothpaste
Given beside what is tested · 2 — Toothpaste is usual care or a partner of the new treatment
- Comparative Efficacy of Floss and Essential Oil/CPC+Zn Mouthwashes in Reducing Dental Plaque and GingivitisCompletedPhase 4Colgate PalmoliveNCT07029438Written as Toothpaste
- Comparative Study of CPC+Zn Mouthwash, Dental Floss, and Essential Oils Mouthwash on Plaque and Gingivitis ReductionCompletedPhase 3Colgate PalmoliveNCT06607263Written as Toothpaste