ClinicalTrials.gg
CompletedNCT07117071Updated Aug 12, 2025

Prevalence of Fuchs Endothelial Corneal Dystrophy in a Population of Dermatology Patients.

An observational study in Fuchs Endothelial Corneal Dystrophy, sponsored by Centre Hospitalier Universitaire de Saint Etienne. Completed at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-08-12.

Sponsored by Centre Hospitalier Universitaire de Saint Etienne · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
1,200
Ages
18 Years and older
Sex
All
01

Study summary

The prevalence of Fuchs Endothelial Corneal Dystrophy (FECD) varies from 3.7 to 21.6% of adults depending on the population studied (country and age class), the method of diagnosis and the definition adopted. In the absence of available data for France, we analyzed the prevalence of Fuchs Endothelial Corneal Dystrophy (FECD) in a specific sub-population.

Read the detailed description

The Primary purpose is to Estimate the prevalence of Fuchs' endothelial dystrophy in the French population in dermatology population.

02

Conditions studied

  • Fuchs Endothelial Corneal Dystrophy

Keywords

  • Fuchs endothelial corneal dystrophy
  • specular microscopy
  • prevalence
  • carcinoma
03

In context

Fuchs' Endothelial Dystrophy

92 studies on the registry are indexed under Fuchs' Endothelial Dystrophy; 27 are open to participants now.

This study's enrollment of 1,200 is above the median of 144 across 26 observational studies indexed under Fuchs' Endothelial Dystrophy.

Browse Fuchs' Endothelial Dystrophy studies →

Lead sponsor

Centre Hospitalier Universitaire de Saint Etienne is the lead sponsor of 597 studies on the registry; 127 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patient with screening of Fuchs endothelial corneal dystrophy will be included.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Patient with screening of Fuchs endothelial corneal dystrophy

Exclusion criteria

Exclusion Criteria:

  • Patients under guardianship
  • Patients unable to receive
  • Patients with anterior segment pathology (declarative) (the eye concerned will not be photographed)
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Informed consent

Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.

You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

05

Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
1,200 participants (actual)
Patient registry
No

Groups and cohorts

  • screening of Fuchs endothelial corneal dystrophy

    Patients with screening of Fuchs endothelial corneal dystrophy will be included.

    Other: collection of medical data

Interventions

  • Othercollection of medical data

    collection of medical data : Age, Sex, Previous cataract surgery, Cellularity, Dermatological pathology, results of screening of Fuchs endothelial corneal dystrophy by Specular microscopy

06

What researchers measure

Primary outcomes

  1. Dark spot in specular microscopy

    Dark sport or guttae after specular microscopy in parallel with the dermatological consultation

    Time frame: Years: 1

Secondary outcomes

  1. Prevalence of Fuchs endothelial corneal dystrophy (FECD) as a function of age

    Prevalence of Fuchs endothelial corneal dystrophy (FECD) as a function of age. Data of medical record will be analyzed.

    Time frame: Years: 1

  2. Prevalence of Fuchs endothelial corneal dystrophy (FECD) as a function of gender

    Prevalence of Fuchs endothelial corneal dystrophy (FECD) as a function of gender. Data of medical record will be analyzed.

    Time frame: Years: 1

  3. Correlation between Fuchs endothelial corneal dystrophy (FECD) and skin pathology

    Correlation between Fuchs endothelial corneal dystrophy (FECD) and skin pathology. Data of medical record will be analyzed.

    Time frame: Years: 1

07

Study locations

1 site
  • CHU Saint-Etienne
    Saint-Etienne, France
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Ran from Jan 2024 to primary completion in Dec 2024, 11 months.

How these figures are worked out, and which studies are left out of them.

Registered
Aug 5, 2025
First posted
Aug 12, 2025
StartActual
Jan 2, 2024
Primary completionActual
Dec 31, 2024
CompletionActual
Dec 31, 2024
Last update
Aug 12, 2025
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Aug 12, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07117071
Responsible party
Sponsor
First posted
Aug 12, 2025
Start date
Jan 2, 2024
Primary completion
Dec 31, 2024
Completion
Dec 31, 2024
Last update
Aug 12, 2025

Study contacts

Philippe GAIN, MD PhD
principal investigator · Centre Hospitalier Universitaire de Saint Etienne

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Aug 2025. You cannot join it, but the record below documents what was studied.

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Discussion

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