Drug
Amphotericin B clinical trials
Also written Fungizone.
Includes 53 studies of Liposomal amphotericin B and 5 studies of Amphotericin B, deoxycholate drug combination.
- studies test it
- 95
- open now
- 11
- in phase 3
- 30
- first study started
- 1997
Keep track of what changes. Save the Amphotericin B studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
79 studies that test it; most in 2006 (7); 1 more planned to start later
| Year | Studies |
|---|---|
| 1997 | 2 |
| 1999 | 1 |
| 2000 | 1 |
| 2002 | 1 |
| 2003 | 4 |
| 2004 | 3 |
| 2005 | 3 |
| 2006 | 7 |
| 2007 | 7 |
| 2008 | 6 |
| 2009 | 1 |
| 2010 | 2 |
| 2011 | 5 |
| 2012 | 2 |
| 2013 | 1 |
| 2014 | 3 |
| 2015 | 1 |
| 2016 | 2 |
| 2018 | 5 |
| 2019 | 4 |
| 2020 | 3 |
| 2021 | 2 |
| 2022 | 2 |
| 2023 | 2 |
| 2024 | 1 |
| 2025 | 4 |
| 2026 | 4 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 1
- 10
- Phase 2
- 27
- Phase 3
- 30
- Phase 4
- 19
- No phase
- 15
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 30 · Other 65
Gilead Sciences (8) · National Institute of Allergy and Infectious Diseases (NIAID) (7) · Pfizer (6) · Drugs for Neglected Diseases (5) · Banaras Hindu University (5) · Assistance Publique - Hôpitaux de Paris (3) · University of Pittsburgh (3) · Matinas BioPharma Nanotechnologies, Inc. (2)
Often tested with
Tested in the same studies.
Fluconazole (11) · Miltefosine (7) · Paromomycin (5) · Voriconazole (5) · Flucytosine (4) · Caspofungin (3) · Itraconazole (2) · Olorofim (1)
Studies
Open first, then newest update. How each study uses Amphotericin B is read from its arms, and is right about nine times in ten.
Testing it · 95
- A Trial to Compare Nebulized Amphotericin B and Nebulized Normal Saline as Maintenance in Patients With Chronic Pulmonary AspergillosisRecruitingPhase 3Post Graduate Institute of Medical Education and Research, ChandigarhNCT06447402Written as Amphotericin B deoxycholate
- Liposomal Amphotericin B and Flucytosine Antifungal Strategy for Talaromycosis (LAmB-FAST)Not yet recruitingPhase 3Duke UniversityNCT06525389Written as Liposomal Amphotericin B (LAmB)
- Safety and Efficacy of Liposomal Amphotericin B for Patients With Invasive Mold Diseases in Liver Transplant RecipientsNot yet recruitingNot applicableBeijing Friendship HospitalNCT07725874Written as AmBisome (Amphotericin B) Liposome
- Amphotericin B for Breakthrough Fungal Infections After Triazole Prophylaxis in Hematological PatientsNot yet recruitingNot applicablePeking University People's HospitalNCT07559032Written as Amphotericin B
- Impact Of The Gut Microbiota On Host Cells Energy Metabolism in Health And In Inflammatory Bowel DiseaseRecruitingPhase 2Assistance Publique - Hôpitaux de ParisNCT07300553Written as Vancomycin /Amphotericin B (Fungizone®) /Gentamicine 80 mg
- Study Comparing Several Drugs to Understand Which Work Against Cutaneous Leishmaniasis (CL)Not yet recruitingPhase 3Institute of Tropical Medicine, BelgiumNCT07463040Written as Liposomal Amphotericin B (LAmB)
- Liposomal Amphotericin B in Invasive Aspergillosis With Hepatic DysfunctionNot yet recruitingNot applicableSoutheast University, ChinaNCT07337720Written as LIposomal amphotericin B (L-AmB) treatment
- Single High-dose of Liposomal Amphotericin B in Combination With B/F/TAF for HIV/AIDS-associated TalaromycosisNot yet recruitingNot applicableShanghai Public Health Clinical CenterNCT06926569Written as Amphotericin B
- Chronic Pulmonary Aspergillosis and Ambisome Aerosol with ItraconazoleRecruitingPhase 3Poitiers University HospitalNCT03656081Written as inhaled Ambisome®
- Treatment of Mucosal Bolivian LeishmaniasisRecruitingPhase 3Fundacion Nacional de DermatologiaNCT04799236Written as Group 3: Liposomal amphotericin B
- Amphotericin B for Non-HIV Cryptococcal Meningitis PatientsEnrolling by invitationPhase 4Huashan HospitalNCT06178627Written as Amphotericin B 0.5 mg/kg/day i.v. combined with flucytosine four times per day orally for the first 4 weeks.
- Olorofim Aspergillus Infection StudyCompletedPhase 3F2G LtdNCT05101187Written as AmBisome®
- Human Bioequivalence Study of Amphotericin B Liposome for InjectionCompletedNot applicableSichuan Huiyu Pharmaceutical Co., LtdNCT06977490Written as Amphotericin B Liposome for Injection (strength: 50 mg, Sichuan Huiyu Pharmaceutical Co., Ltd.)
- Pilot Study of High Dose Liposomal Amphotericin B Efficacy in Initial Zygomycosis TreatmentCompletedPhase 2Assistance Publique - Hôpitaux de ParisNCT00467883Written as Liposomal Amphotericin B
- Efficacy and Safety of Topical Amphotericin B Solution in Treatment of Resistant Tinea Capitis in Children 16 Years Old or Less we Follow up Cases Weekly up to 8 Weeks and Notice Improvement of Itching ,Scaling, and Hair Regrowth Then Fungal Culture Done to See if the Solution WorkingActive, not recruitingPhase 2/3Sohag UniversityNCT06980493Written as Amphotericine in liposome (Ambisome®)
- CAMB/MAT2203 in Patients With Mucocutaneous CandidiasisCompletedPhase 2Matinas BioPharma Nanotechnologies, Inc.NCT02629419Written as Amphotericin B
- Treatment of Cutaneous Leishmaniasis With Liposomal Amphotericin B in the ElderlyCompletedPhase 1/2Hospital Universitário Professor Edgard SantosNCT06449040Written as Liposomal amphotericin B (AmBisome®)
- Bioequivalence of Amphotericin B Liposome for InjectionCompletedPhase 1CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd.NCT05913921Written as Amphotericin B liposome for injection
- Nebulised Liposomal Amphotericin for Invasive Pulmonary Aspergillosis (NAIFI01 Study)CompletedPhase 1Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y CajalNCT04267497Written as Amphotericin B Liposomal 50 MG
- Encochleated Oral Amphotericin for Cryptococcal Meningitis Trial (EnACT)CompletedPhase 1/2Matinas BioPharma Nanotechnologies, Inc.NCT04031833Written as Amphotericin B
See all 95 studies that test Amphotericin B →
Given in every arm · 5 — Amphotericin B is usual care beside what is tested
- Amphotericin Versus Posaconazole for Pulmonary MucormycosisCompletedPhase 2Post Graduate Institute of Medical Education and Research, ChandigarhNCT05468372Written as Liposomal Amphotericin B
- The Deferasirox-AmBisome Therapy for Mucormycosis (DEFEAT Mucor) StudyCompletedPhase 2Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical CenterNCT00419770Written as Liposomal amphotericin B
- Treatment With Tamoxifen in Cryptococcal MeningitisCompletedPhase 2Oxford University Clinical Research Unit, VietnamNCT03112031Written as Amphotericin B
- Efficacy Trial of Ambisome Given Alone and Ambisome Given in Combination With Miltefosine for the Treatment of VL HIV Positive Ethiopian Patients.CompletedPhase 3Drugs for Neglected DiseasesNCT02011958Written as Liposomal Amphotericin B
- Efficacy and Safety of Mycograb as Adjunctive Therapy for Cryptococcal Meningitis in Patients With AIDSTerminatedPhase 2Novartis PharmaceuticalsNCT00847678Written as Amphotericin B
As the comparator · 13 — what is tested is compared with Amphotericin B
- Antifungal Drugs in Pulmonary MucormycosisNot yet recruitingPhase 4Bin CaoNCT06756191Written as Liposomal Amphotericin B
- Pilot Study: Oral Treatment of American Tegumentary Leishmaniasis (Cutaneous and Mucosal Forms) in the ElderlyRecruitingPhase 2/3University of BrasiliaNCT06040489Written as Liposomal Amphotericin B
- A Phase II, Multicentre, Randomized, Two-arm Blinded Study to Assess the Efficacy and Safety of Two LXE408 Regimens for Treatment of Patients With Primary Visceral LeishmaniasisCompletedPhase 2Drugs for Neglected DiseasesNCT05593666Written as AmBisome®
- Liver Transplant European Study Into the Prevention of Fungal InfectionCompletedPhase 3Astellas Pharma IncNCT01058174Written as liposomal amphotericin B
- Micafungin Versus Amphotercine B in Treatment of Invasive Fungal InfectionCompletedPhase 4Ain Shams UniversityNCT06413056Written as Amphotericin B
- Encochleated Oral Amphotericin for Cryptococcal Meningitis Trial 3Status unknownPhase 3Matinas BioPharma Nanotechnologies, Inc.NCT05541107Written as Amphotericin B
- High-Dose Fluconazole for the Treatment of Cryptococcal Meningitis in HIV-Infected IndividualsCompletedPhase 1/2National Institute of Allergy and Infectious Diseases (NIAID)NCT00885703Written as Amphotericin B
- Safety, Tolerability, and Efficacy of Caspofungin Versus Amphotericin B Deoxycholate in the Treatment of Invasive Candidiasis in Neonates and Infants (MK-0991-064)TerminatedPhase 2Merck Sharp & Dohme LLCNCT01945281Written as Amphotericin B Deoxycholate
- Study to Compare the Efficacy and Safety of Micafungin Versus Conventional Amphotericin B for the Treatment of Neonatal CandidiasisTerminatedPhase 3Astellas Pharma Global Development, Inc.NCT00815516Written as amphotericin B deoxycholate
- A Study to Compare the Efficacy and Safety of a Combination of Ketoconazole and Clindamycin Compared to Tetracycline/Amphotericin B Combination Cream for the Treatment of Bacterial Vaginosis and Vaginal Candidiasis (P08077)CompletedPhase 3Merck Sharp & Dohme LLCNCT01293643Written as 100 mg tetracycline hydrochloride /50 mg amphotericin B cream
- Micafungin Versus AmBisome in Invasive Candidiasis and CandidemiaCompletedPhase 3Astellas Pharma IncNCT00106288Written as Liposomal Amphotericin B
- Anidulafungin vs Amphotericin B Safety in High Risk Hepatic Transplant RecipientsCompletedPhase 4Fundacion SEIMC-GESIDANCT01303549Written as Liposomal amphotericin B
- To Study the Effect Of Single Infusions Of Amphotericin B Lipid Preparations in Treatment of Patients Of Kala AzarCompletedPhase 3Bharat Serums and Vaccines LimitedNCT00876824Written as Liposomal Amphotericin B
Codes
What other systems call Amphotericin B · ClinicalTrials.gg INT006963
- MeSH (NLM) D000666Amphotericin BConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 7XU7A7DROEAMPHOTERICIN BConfirmed FDA, NLM, Wikidata
- RxNorm 732Confirmed FDA, Wikidata
- Wikidata Q412223amphotericin BConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C238Amphotericin BOne source FDA
- DrugBank DB00681One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000666 | Amphotericin B | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 7XU7A7DROE | AMPHOTERICIN B | Confirmed FDA, NLM, Wikidata |
| RxNorm | 732 | — | Confirmed FDA, Wikidata |
| Wikidata | Q412223 | amphotericin B | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C238 | Amphotericin B | One source FDA |
| DrugBank | DB00681 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.