An observational study in Endocrine Disease, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). Recruiting at 1 site in United States. Open to participants aged 18 Years to 90 Years. Per ClinicalTrials.gov, last updated 2026-10-26.
Sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · Observational
Background:
Endocrine disorders involve changes to glands that produce hormones. Hormones are released by these glands into the blood so they can direct the function of other tissues in the body. Researchers want to study people who may have endocrine disorders. They want to learn more about the conditions that affect endocrine glands.
Objective:
To study adults with a variety of endocrine disorders for research and physician education.
Eligibility:
Adults ages 18 and older who have an endocrine or metabolic-related disorder
Healthy volunteers 18 and older
Design:
Participants will be screened with a review of their medical records.
Participants will have a physical exam and medical history.
The length of the study and the schedule will vary by participant. Tests may include:
Blood and urine tests
Stool and saliva samples
Imaging studies: Participants will lie on a table while a machine takes pictures of the body. They may be injected with a substance to make their organs more visible in the pictures.
Tests of endocrine tissue function
Consultation with other specialists
Sleep study
Medical photographs
Participants may be treated for their endocrine disorder. This could include:
Surgery. If tissue is removed during surgery, it may be studied.
Radiation
Medicine
Participants may have genetic testing. This will be done with a small amount of blood, cells from a cheek swab, or saliva.
Sponsoring Institution: National Institute of Digestive, Diabetes and Kidney Disease
Study Description:
This study allows the NIH Intramural Endocrinology Training Program (IETP) to follow or provide evaluation, treatment and or interventions to certain eligible subjects.
Objectives:
Endpoints:
322 studies on the registry are indexed under Endocrine System Diseases; 51 are open to participants now.
This study's planned enrollment of 1,000 is above the median of 134 across 88 observational studies indexed under Endocrine System Diseases.
Browse Endocrine System Diseases studies →National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is the lead sponsor of 538 studies on the registry; 55 are open to participants now.
Of its 80 completed or terminated interventional studies of FDA-regulated products, 51 (64%) have results posted.
Counted across the registry records on this site, refreshed daily.
any adult with a potential endocrine disorder; the types of disorders may vary to ensure that there is an adequate case mix of diagnoses for the training program.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
In order to be eligible to participate in this study, an individual must meet all the following criteria:
EXCLUSION CRITERIA:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Adults referred to NIH with possible endocrine conditions
Adults referred to NIH or studied at NIH and determined to have hyperaldosteronism
Device: Creation of side holes in catheters for adrenal vein sampling
one or two side-holes will be created by the interventional radiologist to facilitate adrenal vein sampling
Diagnosis/Treatment
determination of diagnosis and/or treatment of an endocrine disorder
Time frame: variable
Plan to share: Undecided — WE currently have no plan to share this data, but in the future may consider sharing of this data for analysis with collaborators of with other expertise.
Started Mar 2019 (actual). Primary completion is estimated for Jan 2036, 201 months after the start.
Of 32 observational studies under Endocrine System Diseases, half reached primary completion within 43 months of starting (the median), counting those still running; a quarter within 13 and three quarters within 339. This study's planned 201 months is above that.
Endocrine System Diseases covers many different conditions, not one, so the studies compared here vary widely. Read these figures as a rough guide.
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
Contact study teamGet an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) →