Dysthymic Disorder clinical trials
The registry lists 75 studies for Dysthymic Disorder across more than 10 countries. 5 are recruiting or about to start. 11 of them are mainly about Dysthymic Disorder (how this is decided). Per ClinicalTrials.gov, last updated 2026-05-15.
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Breast cancer · Recruiting: 2 came in, 3 changed
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A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
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Who runs them
New York State Psychiatric Institute (20) · Centre for Addiction and Mental Health (4) · West University of Timisoara (3) · University of Washington (3) · Indiana University (2) · St. Luke's-Roosevelt Hospital Center (2) · OM1, Inc. (2) · Massachusetts General Hospital (2)
What is being tested here
Drugs under test in Dysthymic Disorder studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Bupropion | 0 | 0 | 6 |
| Escitalopram | 0 | 0 | 5 |
| Imipramine | 0 | 0 | 3 |
| Duloxetine | 0 | 0 | 3 |
| Levodopa | 0 | 0 | 2 |
| Sertraline | 0 | 0 | 2 |
| Venlafaxine | 0 | 0 | 2 |
| Desvenlafaxine | 0 | 0 | 2 |
| Fluoxetine | 0 | 0 | 1 |
| Donepezil | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 2
- Nov 2026Testing a Precision Psychotherapy System for Low-income Patients · National Council of Scientific and Technical Research, Argentina
- Dec 2026Mindful Self-compassion for Anxiety and Depression: Impact of Delivery Method · Georgetown University
Who these studies take
Of the 4 Dysthymic Disorder studies recruiting now, 0 (0%) set no upper age limit and 4 (100%) stop at 75 or younger. 1 (25%) take children under 18. 1 (25%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 2 (50%) | 2 (50%) |
| 30 | 2 (50%) | 2 (50%) |
| 40 | 3 (75%) | 2 (50%) |
| 50 | 3 (75%) | 2 (50%) |
| 65 | 3 (75%) | 2 (50%) |
| 75 | 0 (0%) | 0 (0%) |
| 85 | 0 (0%) | 0 (0%) |
Across all 75 studies, recruiting or not: 60% stop at 75 or younger and 47% at 65; 24% take children; 5% are for women only and 1% for men only; 4% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 50 of 75. Browse all 75 → or search them.
- Mindful Self-compassion for Anxiety and Depression: Impact of Delivery MethodRecruitingNCT07028216Not applicable1 country
- Transdiagnostic Internet-delivered Intervention for Adolescents With Anxiety and DepressionRecruitingNCT06724666Not applicable1 country
- Testing a Precision Psychotherapy System for Low-income PatientsNot yet recruitingNCT05118594Not applicable
- Dysthymia: Associated Costs, Treatment and Change ProcessRecruitingNCT04911829Not applicable1 country
- Schema Therapy for Chronic DepressionRecruitingNCT03084744Not applicable1 country
- Unobtrusive Monitoring of Affective Symptoms and Cognition Using Keyboard Dynamics (UnMASCK)CompletedNCT043589001 country
- Pramipexole to Target "Anhedonic Depression"CompletedNCT04121091Phase 21 country
- Clinical Effectiveness of TARA Compared to Standard Treatment for Adolescents and Young Adults With DepressionActive, not recruitingNCT04747340Not applicable1 country
- Group Therapy for Women Prisoners With Comorbid Substance Use and DepressionCompletedNCT00606996Not applicable1 country
- Characterizing MyMood Patterns of UseActive, not recruitingNCT046643741 country
- Cognitive Behavioral Therapy (REBT/CBT) Evaluation for Dysthymia in the Practice of Clinical Social Work at Primary CareCompletedNCT02112708Not applicable1 country
- eIMPACT-DM Pilot Trial: Depression Treatment to Reduce Diabetes RiskCompletedNCT04437485Phase 21 country
- eIMPACT Trial: Modernized Collaborative Care to Reduce the Excess CVD Risk of Older Depressed PatientsCompletedNCT02458690Phase 21 country
- A Study of L-DOPA for Depression and Slowing in Older AdultsCompletedNCT02744391Phase 41 country
- L-DOPA vs. Placebo for Depression and Psychomotor Slowing in Older AdultsTerminatedNCT03761030Phase 41 country
- Online System for Identifying and Addressing Teen Depression in Primary CareStatus unknownNCT044894851 country
- Implementation of Harmonized Depression Outcome Measures in a Primary Care Registry and a Mental Health RegistryCompletedNCT042357251 country
- Implementation of Harmonized Depression Outcome Measures in a Health SystemCompletedNCT042357121 country
- Antidepressant Response in the Treatment of Depressive Symptoms and Frailty Characteristics in Older AdultsCompletedNCT01973283Phase 41 country
- Treatment of Adolescent Suicide Attempters (TASA)CompletedNCT00080158Phase 2/31 country
- Treating Emotional Disorders in Primary Care With Psychological TechniquesCompletedNCT01903096Phase 41 country
- Oxytocin Add-on for Stable Depressed PatientsTerminatedNCT01211756Not applicable1 country
- Medications for the Treatment of Dysthymic Disorder and Double DepressionCompletedNCT00234312Phase 41 country
- A Trial of Sertraline vs. CBT for End-stage Renal Disease Patients With Depression {ASCEND}CompletedNCT02358343Phase 31 country
- Dichotic Listening as a Predictor of Medication Response in DepressionCompletedNCT00296725Phase 1/21 country
- Effects of Therapist Behavior on the Treatment of Depressed AdolescentsCompletedNCT00073359Phase 1/21 country
- A Comparison of Medication Augmentation and PST in the Treatment of Depression in Older AdultsWithdrawnNCT01942187Phase 41 country
- Clinical Trial of CBASP for Individuals With Co-occurring Chronic Depression and Alcohol DependenceCompletedNCT015287481 country
- RECOVERY: A Transdiagnostic Intervention for Anxiety and DepressionStatus unknownNCT03917550Not applicable1 country
- A Trial of Cognitive Behavioral Therapy in Familial DysautonomiaCompletedNCT03013777Not applicable1 country
- Can E-therapies Reduce Waiting Lists in Secondary Mental Health Care? A Randomized Controlled TrialStatus unknownNCT02423733Not applicable1 country
- Dichotic Listening as a Predictor of Medication Response in DepressionCompletedNCT00404755Phase 41 country
- Rumination Focus Cognitive Behavior TherapyStatus unknownNCT03507114Not applicable1 country
- Sertraline in Generalized Social Phobia With Co-Occurring Anxiety and Mood DisordersTerminatedNCT00182533Phase 41 country
- Combination Treatment Study for Memory Impairment and DepressionCompletedNCT01658228Phase 41 country
- Desvenlafaxine vs. Placebo Treatment of Chronic DepressionCompletedNCT01537068Phase 41 country
- Duloxetine for Chronic Depression: a Double-blind StudyCompletedNCT00360724Phase 41 country
- Treating Depression Among Low-Income Patients With CancerCompletedNCT00565110Not applicable1 country
- Behavioral Activation (BA) for Medication-responsive Chronically Depressed Patients With Impaired Social FunctioningCompletedNCT01783080Not applicable1 country
- Cognitive Therapy for Unipolar Depression: Efficacy of a Dilemma-Focused InterventionCompletedNCT01542957Not applicable1 country
- The Influence of the Menstrual Cycle on Lithium and Sertraline Blood LevelsCompletedNCT013857091 country
- Treatment for Depressed, Obese Individuals at Risk for Cardiovascular Disease (CVD)CompletedNCT01692574Not applicable1 country
- Internet-delivered Transdiagnostic Intervention for Anxiety and DepressionStatus unknownNCT02739607Not applicable1 country
- Using Mental Health Telemetry to Predict Relapse and Re-hospitalization in Mood DisordersCompletedNCT01882608Not applicable1 country
- Bringing What Works to Youth in Corrections: A Trauma InterventionCompletedNCT01560728Phase 1/21 country
- Motivational Interviewing and Cognitive Behavioral Therapy-based Intervention for Cardiovascular Disease Prevention Amongst American Indians With Diabetic and Depressive SymptomsCompletedNCT01892124Not applicable1 country
- Wellbutrin XL for Dysthymic DisorderCompletedNCT00225251Phase 41 country
- Escitalopram in the Treatment of Dysthymic Disorder, Double BlindCompletedNCT00220701Phase 41 country
- Project to Improve Symptoms and Mood in People With Spinal Cord InjuryCompletedNCT00592384Phase 41 country
- Desvenlafaxine Monotherapy in DysthymiaCompletedNCT01948895Not applicable1 country