An observational study in Spasmodic Dysphonia and Quality of Life, sponsored by Manchester University NHS Foundation Trust. Completed at 1 site in United Kingdom. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-09-23.
Sponsored by Manchester University NHS Foundation Trust · Observational
Previous research has shown that patients with voice disorders often have a lower quality of life and struggle with employment. Spasmodic Dysphonia (SD) is a voice disorder that causes abrupt and uncontrollable spasms of the voice box, often resulting in the person having lifelong changes in their voice and speech pattern. The current mainstay of treatment is injecting botulinum toxin (BT) injections into the vocal cord to ease the spasms. The same research team conducted a pilot study in April 2021 on patients with SD. The pilot study used questionnaires and short interviews to understand the livelihood of 10 SD patients. It displayed that SD may impact patients' quality of life. The investigators now aim to run an official research project, ethically approved, to explore the following questions further:
To answer these questions, the investigators aim to interview 20 patients with Spasmodic Dysphonia.
132 studies on the registry are indexed under Dysphonia; 38 are open to participants now.
This study's enrollment of 22 is below the median of 123 across 40 observational studies indexed under Dysphonia.
Browse Dysphonia studies →Manchester University NHS Foundation Trust is the lead sponsor of 140 studies on the registry; 27 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Adult patients with diagnosed Spasmodic Dysphonia
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Exclusion Criteria:
Adults diagnosed with Spasmodic Dysphonia who have received at least one botulinum toxin injection.
Procedure: Botulinum toxin injections
Botulinum toxin injection to ease spasms of vocal cord
Does Spasmodic Dysphonia impact the socio-economic lives of its patients? If so, how?
Outcome will be measured through qualitative analysis of participant answers regarding how the target condition, spasmodic dysphonia, affects the social and economic aspects of their livelihood.
Time frame: Through study completion, which is expected to be a year
What role do botulinum toxin injections play in the socio-economic livelihood of Spasmodic Dysphonia patients?
Outcome will be measured through qualitative analysis of participant answers regarding how receiving Botulinum toxin injections may improve their livelihood.
Time frame: Through study completion, which is expected to be a year
Plan to share: No — Individual participant data will not be shared due to the sensitive nature of the study content and the interview study design
No publications or documents are linked to this record.
Ran from Aug 2024 to primary completion in Aug 2025, 12 months.
Of 18 observational studies under Dysphonia, half reached primary completion within 26 months of starting (the median), counting those still running; a quarter within 12 and three quarters within 193. This study's 12 months is below that.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.
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Manchester University NHS Foundation Trust →