AbbVie: Dry Eye Syndromes trials

The registry lists 49 Dry Eye Syndromes studies with AbbVie as lead sponsor. 1 are open to participants now and 41 have results posted.

Phase 1 4Phase 2 5Phase 3 13Phase 4 9No phase 20(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• A Study to Assess Adverse Events, How the Drug Moves Through the Body and Effectiveness of Intravenous Infusions of ABBV-319 in Adult Participants With Systemic Lupus Erythematosus (SLE), Sjogren's Disease (SjD) and Rheumatoid Arthritis (RA)RecruitingNCT06977724Phase 1
• A Study to Assess Symptom Relief and Product Tolerability of ABBV-444 Drops in Adult ParticipantsCompletedNCT05878067Phase 3Results posted
• Efficacy and Safety of a New Artificial Tear Formulation Compared With Systane Ultra Multidose in Participants With Dry Eye DiseaseCompletedNCT04393441Phase 3Results posted
• A Study of the Drugs AGN-242428 and AGN-231868 in Participants With Dry Eye DiseaseCompletedNCT04030962Phase 1/2Results posted
• Goblet Cell Degranulation Produced by Intranasal Tear Neurostimulator (ITN) in Dry Eye DiseaseTerminatedNCT03827564Not applicableResults posted
• Clinical Trial to Evaluate the Symptoms in Symptomatic Contact Lens Wearers Following Application of Intranasal Tear Neurostimulator Versus ControlCompletedNCT03325673Not applicableResults posted
• Clinical Study to Evaluate Tear Characteristics Following Acute TrueTear™ UseTerminatedNCT03274999Not applicableResults posted
• Safety and Efficacy of TrueTear™ for the Treatment of Meibomian Gland DiseaseCompletedNCT03226769Not applicableResults posted
• Optive Brand For Day And Night Dry Eye ManagementCompletedNCT03208673Not applicableResults posted
• Topical Ophthalmic AGN-195263 for the Treatment of Evaporative Dry EyeTerminatedNCT02965846Phase 3Results posted
• Evaluation of Dry Eye Symptoms in CAE With Application of Intranasal NeurostimulationCompletedNCT02910713Not applicableResults posted
• Topical Ophthalmic AGN-195263 for the Treatment of Evaporative Dry EyeTerminatedNCT02815293Phase 3Results posted
• Evaluation of Maintaining Visual Performance in Participants Who Engage in Electronic Visual Tasking While Using Restasis®CompletedNCT02554981Phase 4Results posted
• A Safety and Efficacy Study of a New Eye Drop Formulation in Patients With Dry Eye Disease.CompletedNCT02553772Phase 3Results posted
• A Study to Compare a New Eye Drop Formulation With Systane® Gel Drops and Genteal® Lubricant Gel Drops for Moderate to Severe Dry Eye ReliefCompletedNCT02455050Phase 3Results posted
• Safety, Efficacy, Tolerability and Pharmacokinetics of AGN-223575 Ophthalmic Suspension in Patients With Dry Eye DiseaseCompletedNCT02435914Phase 2Results posted
• Evaluation of the Safety and Effectiveness of the Oculeve Intranasal Lacrimal Neurostimulator in Patients With Dry EyeCompletedNCT02313454Not applicableResults posted
• A Safety and Efficacy Study of Refresh Optive® Gel Drops in Patients With Dry Eye DiseaseCompletedNCT02280473Phase 3Results posted
• Investigation of Maintaining Visual Performance Achieved With Cyclosporine TherapyCompletedNCT02121847Phase 4Results posted
• A Safety and Efficacy Study of OPTIVE FUSION™ With VISMED® Multi for the Management of Dry EyeCompletedNCT02117687Phase 4Results posted
• A Study of Sodium Carboxymethylcellulose for Post Cataract Surgery Dry Eye SymptomsCompletedNCT02028754Phase 4Results posted
• Phase 2 Study of a New Ophthalmic Formulation of Cyclosporine (Restasis® X) in Patients With Dry Eye DiseaseTerminatedNCT02013791Phase 2Results posted
• A Study to Determine the Prevalence of Inflammatory Dry Eye Disease in Patients Prior to Cataract RemovalCompletedNCT01882413Results posted
• An Observational Study of Dry Eye Prior to Laser-Assisted in Situ Keratomileusis (LASIK) TherapyCompletedNCT01854905Results posted
• An Observational Study of OPTIVE PLUS® for the Treatment of Dry Eye DiseaseCompletedNCT01711424Results posted
• Safety and Efficacy of Punctal Plug Insertion in Patients With Dry EyeCompletedNCT01684436Phase 4Results posted
• A Study to Compare the Safety and Efficacy of A New Eye Drop Formulation With OPTIVE™ in Subjects With Dry Eye DiseaseCompletedNCT01664949Phase 3Results posted
• Safety, Efficacy, and Acceptability Study of an Eye Drop Formulation in Subjects With Dry Eye DiseaseCompletedNCT01459588Phase 3Results posted
• Study of Two Formulations of Cyclosporine Ophthalmic Emulsion in Healthy Volunteers and in Patients With Dry EyeCompletedNCT01319773Phase 1Results posted
• Safety and Efficacy Study of New Eye Drop Formulations With Refresh Tears® in Patients With Dry Eye DiseaseCompletedNCT01294384Phase 3Results posted
• Effects of Cataract Extraction Surgery and Limbal Relaxing Incision on Corneal Sensation and Dry EyeCompletedNCT01161771Results posted
• Safety and Efficacy of Two Artificial Tears in Dry Eye SubjectsCompletedNCT01010282Not applicableResults posted
• Safety and Efficacy of Carboxymethylcellulose for Ocular Surface Integrity in Symptomatic Dry EyeCompletedNCT00987727Phase 4Results posted
• Study to Compare the Efficacy and Safety of Two Non-Preserved Artificial Tears for the Treatment of Dry Eye Signs and SymptomsCompletedNCT00938704Phase 4Results posted
• Safety and Tolerability of Artificial Tears in Dry Eye SubjectsCompletedNCT00932477Not applicableResults posted
• Physician's Evaluation of Cyclosporine Ophthalmic Emulsion 0.05%CompletedNCT00827255Results posted
• Performance and Acceptance of Optive Versus Hylocomod Eyedrops in Patients With Dry Eye SymptomsCompletedNCT00761202Phase 4Results posted
• Efficacy and Acceptability of Two Lubricant Eye DropsCompletedNCT00756678Phase 4Results posted
• Efficacy Study of Cyclosporine Ophthalmic Emulsion in Patients With Dry Eye DiseaseCompletedNCT00717418Results posted
• Safety and Efficacy Study of Cyclosporine Ophthalmic Emulsion in Post-LASIK PatientsCompletedNCT00611403Phase 2Results posted
• Evaluate the Safety and Efficacy of a New Artificial Tear for Use After LASIK SurgeryCompletedNCT00544713Not applicableResults posted
• Safety and Efficacy of an Artificial Tear for the Treatment of Dry EyeCompletedNCT00514852Not applicableResults posted
• A Clinical Study to Evaluate the Effect and Side Effect of a New Artificial Tear Formulation (ABBV-444) Compared to Refresh Optive Unit Dose in Adult Participants With Dry Eye DiseaseCompletedNCT07284381Phase 3
• An Observational Study to Assess Next Generation Emulsion Preservative Free Eye Drops (NGE-UD) on Dry Eye Symptoms and Quality of Life of Adult Participants With Mild to Moderate Dry Eye Disease (DED)CompletedNCT06443775
• An Observational Study to Assess Optive MEGA-3 (OM3) on Dry Eye Symptoms and Quality of Life of Adult Participants With Mild to Moderate Dry Eye Disease (DED)CompletedNCT06439394
• Safety, Tolerability and Systemic Pharmacokinetics of AGN-232411 in Healthy Participants and Participants With Dry EyeCompletedNCT02420730Phase 1
• A Natural History Study of Patients With Dry EyeCompletedNCT00833235
• A Multi-Center Randomized Study to Evaluate the Efficacy and Safety of an Investigational Lubricant Eye DropCompletedNCT00243711Phase 2/3
• Six Month Clinical Research Study for Patients With Moderate or Severe Dry Eye SyndromeCompletedNCT00025818Phase 3