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Cluster Headache clinical trials

The registry lists 123 studies for Cluster Headache across more than 10 countries. 26 are recruiting or about to start. 101 of them are mainly about Cluster Headache (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.

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A study of drug A after surgery for early breast cancer

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Status

Completed
63
Recruiting
18
Terminated
16
Status unknown
11
Not yet recruiting
6
Active, not recruiting
5

Phase

Phase 2
20
Phase 3
19
Phase 1
9
Phase 4
6

Where

United States
38
Denmark
20
Germany
18
United Kingdom
18
France
16
Netherlands
15

Who runs them

Autonomic Technologies, Inc. (6) · Danish Headache Center (6) · Leiden University Medical Center (5) · Norwegian University of Science and Technology (5) · The University of Texas Health Science Center, Houston (5) · Assistance Publique Hopitaux De Marseille (4) · University Hospital, Ghent (3) · Teva Branded Pharmaceutical Products R&D, Inc. (3)

What is being tested here

Drugs under test in Cluster Headache studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Botulinum toxin type A113
Lysergic Acid Diethylamide102
Methylprednisolone112
Capsaicin101
Zavegepant101
JZP258101
Magnesium Sulfate101
Acetaminophen101
Bupivacaine101
Galcanezumab033

Drug classes tested here Serotonin receptor agonists 1 open · Psychedelics 1 open · CGRP receptor antagonists 1 open · Corticosteroids 1 open

Coming up

3phase 3 studies under way
7studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 7

Who these studies take

Of the 18 Cluster Headache studies recruiting now, 7 (39%) set no upper age limit and 6 (33%) stop at 75 or younger. 4 (22%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 4 (22%) take healthy volunteers.

Recruiting studies that take each age, of 18
AgeWomenMen
102 (11%)2 (11%)
1816 (89%)16 (89%)
3017 (94%)17 (94%)
4017 (94%)17 (94%)
5017 (94%)17 (94%)
6517 (94%)17 (94%)
7513 (72%)13 (72%)
8510 (56%)10 (56%)

Across all 123 studies, recruiting or not: 59% stop at 75 or younger and 37% at 65; 9% take children; 0% are for women only and 1% for men only; 15% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Cluster Headache studies take

Of 26 interventional studies with no phase under Cluster Headache, half reached primary completion within 19 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Interventional, no phase19 mo10–25 · 26 studies——

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 11, 2026.

Started recruiting1

Studies

Recruiting first, then most recently updated. Showing 50 of 123. Browse all 123 → or search them.