Clubfoot clinical trials
The registry lists 69 studies for Clubfoot across more than 10 countries. 15 are recruiting or about to start. 61 of them are mainly about Clubfoot (how this is decided). Per ClinicalTrials.gov, last updated 2026-08-10.
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Who runs them
University of British Columbia (6) · Riphah International University (4) · Shriners Hospitals for Children (3) · Assiut University (3) · Region Stockholm (3) · Orthopedic Hospital Vienna Speising (2) · Muhammad Aamir Latif (2) · Texas Scottish Rite Hospital for Children (2)
What is being tested here
Drugs under test in Clubfoot studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Botulinum toxin type A | 0 | 0 | 3 |
| Onabotulinum toxin A | 0 | 0 | 2 |
| Botulinum Toxins | 0 | 0 | 1 |
| Clonidine | 0 | 0 | 1 |
| Sucrose | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 2
- Feb 2027Midfoot Osteotomy Versus 8-Plate Epiphysiodesis for Residual Metatarsal Adductus · Assiut University
- Oct 2027Ultrasound Assessment of Achilles Tendon-Neurovascular Distance in Infants With Unilateral Clubfoot · Assiut University
Who these studies take
Of the 10 Clubfoot studies recruiting now, 0 (0%) set no upper age limit and 10 (100%) stop at 75 or younger. 9 (90%) take children under 18. 1 (10%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (20%) | 2 (20%) |
| 18 | 2 (20%) | 1 (10%) |
| 30 | 1 (10%) | 0 (0%) |
| 40 | 1 (10%) | 0 (0%) |
| 50 | 0 (0%) | 0 (0%) |
| 65 | 0 (0%) | 0 (0%) |
| 75 | 0 (0%) | 0 (0%) |
| 85 | 0 (0%) | 0 (0%) |
Across all 69 studies, recruiting or not: 86% stop at 75 or younger and 84% at 65; 86% take children; 3% are for women only and 1% for men only; 17% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Clubfoot studies take
Of 20 interventional studies with no phase under Clubfoot, half reached primary completion within 11 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 11 mo9–37 · 20 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 69. Browse all 69 → or search them.
- Comparing Outcomes and Complications Following Mastisol Application for Clubfoot CastingRecruitingNCT07154550Not applicable1 country
- Percutaneous Achilles Tendon Tenotomy vs Tendo-Achilles Lengthening (TAL) in Neglected Clubfoot Children.RecruitingNCT075616971 country
- Comparison of Radiological Outcome of Conventional vs Accelerated Ponseti Casting Technique for Treatment of Club FootRecruitingNCT07554092Not applicable1 country
- Midfoot Osteotomy Versus 8-Plate Epiphysiodesis for Residual Metatarsal AdductusNot yet recruitingNCT07466043Not applicable
- Ultrasound Assessment of Achilles Tendon-Neurovascular Distance in Infants With Unilateral ClubfootNot yet recruitingNCT07473908
- Effects Of French Method With/Without Brace In Clubfoot TreatmentRecruitingNCT07428902Not applicable1 country
- Improving STEP in Stroke PatientsNot yet recruitingNCT07403149Not applicable
- Custom CAD/CAM Insoles for Plantar Pressure Improvement in Foot DeformitiesNot yet recruitingNCT07136649Not applicable
- Original Denis Brawn Brace Versus Its Modification for Management of Relapsed Idiopathic Clubfoot Following Ponseti CastingRecruitingNCT071257941 country
- Prospective Evaluation of Treatment for ClubfootRecruitingNCT022572291 country
- Health-Related Quality of Life in Children and Adolescents With ClubfootRecruitingNCT069064061 country
- Management of Congenital Talipes Equinovarus by Saleem's ProtocolRecruitingNCT05957627Not applicable1 country
- SPLATT to Peroneus Brevis vs TATT to Lateral CuneiformEnrolling by invitationNCT06300645Not applicable1 country
- Evertor Muscle Activity as a Predictor of Achilles Tenotomy in the Management of Idiopathic Varus Equinus ClubfootRecruitingNCT05767762Not applicable1 country
- Study on Prenatal Diagnosis and Closed-loop Management System of Congenital Talipes EquinovarusRecruitingNCT056384901 country
- Comparison of Surgical Blade No. 11 and Ophthalmic Knife in Idiopathic Clubfoot PatientsCompletedNCT075617361 country
- Outcomes of Eight-Plate Epiphysiodesis for Residual Clubfoot DeformitiesCompletedNCT076213281 country
- Clubfoot Tenotomy TrialCompletedNCT04766684Phase 41 country
- Myofascial Release And Static Stretching Along With Nighttime BracingCompletedNCT07249684Not applicable1 country
- IMU-based Assessment of Motor Control in a Population of Young Subjects With Paramorphisms and DysmorphismsCompletedNCT05763901Not applicable1 country
- Therapeutic Recommendations Based on Clinical History and Video Documented PBS-ScoreCompletedNCT060505641 country
- Video Documented PBS-Score in Children With ClubfootCompletedNCT060336381 country
- Predictive Value of the PBS-score in Children With ClubfootActive, not recruitingNCT060507461 country
- Clinical Effectiveness of the Modified WalkFlex DB Splint in Children With Congenital Talipes Equinovarus (CTEV)Active, not recruitingNCT07055672Not applicable1 country
- Novel Dynamic Foot Abduction Bar for Treatment of ClubfootCompletedNCT05293743Not applicable1 country
- The Effect of Physiotherapy on Lower Extremity Function and Gait in Children with Isolated Gastrocnemius Muscle TightnessCompletedNCT06678139Not applicable1 country
- Three Phase Physical Therapy in Children With Relapsed Club Foot After Ponseti TreatmentCompletedNCT06407739Not applicable1 country
- Physiological and Functional Effects of Percutaneous Neuromodulation vs Transcutaneous NeuromodulationActive, not recruitingNCT06365931Not applicable1 country
- Outcome After Needle vs Blade Achilles Tenotomy in ClubfootCompletedNCT04897100Not applicable1 country
- Low Dye Taping Technique Versus Robert Debre Method On Foot Posture And Range Of Motion In Children With Club Foot.CompletedNCT05794334Not applicable1 country
- Clubfeet and Twins and Gait AnalysisActive, not recruitingNCT059139341 country
- Physiotherapy Program Effect on Musculoskeletal Dysfunctions in Young Football PlayersStatus unknownNCT05798988Not applicable1 country
- Translation, Validity, and Reliability of the Foot Posture Index (FPI-6) - Turkish VersionCompletedNCT055790541 country
- Gait Analysis in Idiopathic Clubfoot Patients Treated by the Ponseti MethodCompletedNCT055724111 country
- Functional Assessment in Children With ClubfootCompletedNCT054567371 country
- Using Botox to Treat Patients With Idiopathic ClubfootStatus unknownNCT00474032Not applicable1 country
- Pedobarographic Assessments of Clubfoot Treated PatientsCompletedNCT001757081 country
- Economic Evaluation of Clubfoot Treatment: One Centre's ExperienceWithdrawnNCT00475631
- Efficacy of Botox in Patients With Idiopathic ClubfootCompletedNCT00152334Not applicable1 country
- Genetic Linkage Study of Idiopathic Talipes Equinovarus (ITEV) (Clubfoot)CompletedNCT004743442 countries
- Customized Orthosis for Children With ClubfootTerminatedNCT03853811Not applicable1 country
- Duration of Brace Wear in Clubfoot Treatment - A Prospective Randomized TrialCompletedNCT01551264Not applicable1 country
- Clonidine for Tourniquet-related Pain in ChildrenStatus unknownNCT04564430Phase 41 country
- Comparison of Ponseti Method Versus Older Treatments in Talipes Equinovarus Through Gait Analysis and Clinical ResultsWithdrawnNCT035807461 country
- CGH Array in Bilateral ClubfootStatus unknownNCT04737083
- Pronostic Factors of Long Term Outcome in Patients With Clubfoot Treated by the Ponseti MethodStatus unknownNCT046930651 country
- Smart Phone-Based Application for Evaluation and Rehabilitation of HindFoot PainStatus unknownNCT04423900Not applicable1 country
- Bracing Compliance and Personality Traits: A Compliance Assessment Program for Scoliosis and ClubfeetCompletedNCT027557661 country
- Describing the Effects of Insoles in Children With Increased Femoral Anteversion and Pes PlanovalgusCompletedNCT03812822Not applicable1 country
- Assessment of Gait After Dysport TreatmentCompletedNCT03501043Phase 41 country