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RecruitingNCT07130864Updated Aug 19, 2025

Early vs Late Laparoscopic Cholecystectomy After Common Bile Duct Stones Clearance Through Ercp.

An interventional study of Early cholecystectomy and Late cholecystectomy in Laparoscopic Cholecystectomy, Choledocholithiasis and ERCP, sponsored by Khyber Teaching Hospital. Recruiting at 1 site in Pakistan. Per ClinicalTrials.gov, last updated 2025-08-19.

Sponsored by Khyber Teaching Hospital · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Primary completion was expected by Dec 2025, 10 months ago, but the record still lists the study as recruiting.
  • Started May 2025; still recruiting 1 year 5 months later.
Phase
Not applicable
Study type
Interventional
Enrollment
136
Allocation
Randomized
Sex
All
01

Study summary

There is controversy about timing of cholecystectomy after the common bile duct is cleared of stones. our study aims to compare the results of early vs late cholecystectomy.

02

Conditions studied

  • Laparoscopic Cholecystectomy
  • Choledocholithiasis
  • ERCP
  • Bile Duct Injury

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03

In context

Choledocholithiasis

109 studies on the registry are indexed under Choledocholithiasis; 24 are open to participants now.

This study's planned enrollment of 136 is above the median of 100 across 76 interventional studies indexed under Choledocholithiasis.

Browse Choledocholithiasis studies →

Lead sponsor

Khyber Teaching Hospital is the lead sponsor of 29 studies on the registry; 19 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

.All patients undergoing laparoscopic cholecystectomy who had concomitant choledocholithiasis for which ercp is done.

Exclusion criteria

exclusion criteria:

.Non consenting indviduals

05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Care provider)
Enrollment
136 participants (estimated)

Study arms

  • Experimental
    Early Group

    Early group consist of those patients whose cholecystectomy is performed within 72 hours of ERCP .

    Procedure: Early cholecystectomy

  • Experimental
    Late group

    Late group consist of those patients whose cholecystectomy is performed after 72 hours of ERCP.

    Procedure: Late cholecystectomy

Interventions

  • ProcedureEarly cholecystectomy

    Early cholecystectomy is performed within 72 hours of ERCP.

  • ProcedureLate cholecystectomy

    Late cholecystectomy is performed after 72 hours of ERCP

06

What researchers measure

Primary outcomes

  1. Difficulty level of cholecystectomy

    the presence of diffuse pericholecystic scar adhesions, Calot's triangle with intense fibrosis, atrophic gallbladder, presence of a cholecysto-enteric or cholecyto-choledochal fistula, presence of necrotic changes, liver abscess or the presence of impacted stones and the help of a senior colleague will be considered a difficult cholecystectomy

    Time frame: From start of surgery till end, On day 1 of surgery

Secondary outcomes

  1. Bile duct injury

    Bile duct injury that ocuurs intraoperatively or detected in postoperative period

    Time frame: From the day 1 of surgery till one month

  2. Hospital stay

    Hospital stay determined from day of surgery till discharge

    Time frame: from day 1 of surgery till discharge, upto 1 month

07

Study locations

1 of 1 sites recruiting
08

References and documents

Individual participant data

Plan to share: No — Patients confidentiality maybe breached

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 19, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07130864
Lead sponsor
Khyber Teaching Hospital
Responsible party
Dr Saeed Sarwar (Doctor, Khyber Teaching Hospital) — Principal investigator
First posted
Aug 19, 2025
Start date
May 23, 2025
Primary completion
Dec 30, 2025 (estimated)
Completion
Dec 31, 2025 (estimated)
Last update
Aug 19, 2025

Study contacts

Saeed Sarwar, MBBS
Contact
saeedkmc2020@gmail.com
+923420973863

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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